"Wegovy Rewired My Brain"

[Ghoul]

Something that's been casually observed for years, GLP class drugs soon to be a major component in treating addictions of all kinds.

“Wegovy rewired my brain. I have no desire for cigarettes and minimal desire for alcohol.”

How a Fortune 50 VP controlled his "20 pack-year" and a 5- to 6-drink a night habits.

recursiveadaptation.com

 

[MindlessWork]

Now will this become a wonder brain drug?

 

[Grey Spartan]

Will be interesting to see if it "sticks" after cessation of treatment. Will also be interesting to see the ratio of responders/non-responders. I bet if combined with psychological treatment the success rate will be through the roof.

 

[MindlessWork]

Will be interesting to see if it "sticks" after cessation of treatment. Will also be interesting to see the ratio of responders/non-responders. I bet if combined with psychological treatment the success rate will be through the roof.

Most likely then Wegovy and maybe other GLPs would be a part of the treatment plan including with other drugs for those which have no bad interactions with GLPs.

 

[Ghoul]

Will be interesting to see if it "sticks" after cessation of treatment. Will also be interesting to see the ratio of responders/non-responders. I bet if combined with psychological treatment the success rate will be through the roof.

It doesn't, mostly, for "food addiction". However, since it looks like these other substances "hijaak" the same powerful psychological mechanism that drives appetite (think "cocaine noise", "nicotine noise" being similar to the "food noise" people mention disappearing on a GLP), these other substance addictions aren't fundamentally hardwired like "food addiction" is and may be able to be dislodged completely.

Then yeah, the key is to make sure people don't reexpose themselves to something they're already vulnerable to getting addicted to.

Or just stay on a GLP, because frankly, the inflammation reduction alone is pretty close
to the fountain of youth.

A decade ago, when the extremely expensive short term GLPs were used by a small group of diabetics who could afford them, doctors were mentioning these "sickly" diabetics seemed to develop less disease than "healthy" non-diabetic counterparts.

 

[Grey Spartan]

Or just stay on a GLP, because frankly, the inflammation reduction alone is pretty close
to the fountain of youth.

Well ya, this would be awesome, but how many Docs will keep someone on the drug permanently.

 

[Ghoul]

Well ya, this would be awesome, but how many Docs will keep someone on the drug permanently.

Dr Tracy at the Q clinic will do it
for $50 a year...lol

In all seriousness, GLPs start to go generic in a few years, and there are more insurance covered indications for it every few months, so the covered pool keeps getting larger.

 

[Grey Spartan]

Dr Tracy at the Q clinic will do it
for $50 a year...lol

In all seriousness, GLPs start to go generic in a few years, and there are more insurance covered indications for it every few months, so the covered pool keeps getting larger.

LOL! Oh, I have a few years supply.

I'm even on my way to talk to the Doc at the VA

I will keep you posted on what they say.

 

[BamaCrazy]

LOL! Oh, I have a few years supply.

I'm even on my way to talk to the Doc at the VA

I will keep you posted on what they say.

They require you to participate in their Move Weight Management Program. There was a long waiting list where I live. I dropped 45 pounds in 3 months waiting to get in. Now I don’t qualify.

But my TriCare doc prescribed Wegovy back in the Summer and insurance is covering it. I don’t need or use it. I think my Wife is supplying her friends. lol

 

[Ghoul]

LOL! Oh, I have a few years supply.

I'm even on my way to talk to the Doc at the VA

I will keep you posted on what they say.

Good luck! Pharma is certainly preferable. But given my experience with sudden shortages or insurance problems, keep using the UGL until you have a supply of 3-6 months of pens built up, so once you start on pharma, you can stay on it. The number of times I've heard "we can't fill that right now try in a few weeks" is unbelievable.

 

[Ghoul]

They require you to participate in their Move Weight Management Program. There was a long waiting list where I live. I dropped 45 pounds in 3 months waiting to get in. Now I don’t qualify.

But my TriCare doc prescribed Wegovy back in the Summer and insurance is covering it. I don’t need or use it. I think my Wife is supplying her friends. lol

I'd say the mandated fitness program participation is BS, but the truth is, every insurance plan requires it as well and doctors and their patients just lie.

They should at least require a quick web based course in how to manage sides, and eat properly on it though imo. Would save a lot of people from misery in the toilet and unnecessary muscle loss.

I took advantage of the "be on a diet plan" requirement, which again almost no one actually fulfills, to get insurance to pay for a sports nutritionist consult every month, lol.

 

[Grey Spartan]

They require you to participate in their Move Weight Management Program. There was a long waiting list where I live. I dropped 45 pounds in 3 months waiting to get in. Now I don’t qualify.

But my TriCare doc prescribed Wegovy back in the Summer and insurance is covering it. I don’t need or use it. I think my Wife is supplying her friends. lol

Ya, I have completed the MOVE! program. They refused to give me semaglutide. I'm technically obese, however, the nurse practitioner said I was "vain" when she saw me?! lol The funny thing is, they have no problem giving me amphetamines but not the drugs that will help my entire body with less side effects.

 

[BamaCrazy]

Ya, I have completed the MOVE! program. They refused to give me semaglutide. I'm technically obese, however, the nurse practitioner said I was "vain" when she saw me?! lol The funny thing is, they have no problem giving me amphetamines but not the drugs that will help my entire body with less side effects.

Yep. They will give me ambien, SSRIs, ADD meds, etc but not test or weight loss meds. Such an odd system.

 

[Grey Spartan]

Yep. They will give me ambien, SSRIs, ADD meds, etc but not test or weight loss meds. Such an odd system.

They don't want a bunch of trained, jacked hard charges running around not under their control. lol

 

[TurboJet]

I seen this posted on another forum.

Out-of-control Ozempic use means sad, saggy future for TL;DR generation | Blaze Media

What seems like a quick cosmetic fix is wreaking long-term havoc on Gen Z's mental and physical health.

www.theblaze.com

*I'm not familiar with the blaze or it's quality of reporting.

 

[Ghoul]

I seen this posted on another forum.

Out-of-control Ozempic use means sad, saggy future for TL;DR generation | Blaze Media

What seems like a quick cosmetic fix is wreaking long-term havoc on Gen Z's mental and physical health.

www.theblaze.com

*I'm not familiar with the blaze or it's quality of reporting.

Of course the "counterpoint" articles are written to gather attention, and there are still holdouts who are convinced metabolic regulation isn't a thing, but merely a lack of willpower (which of course they possess and fatties don't). Plenty of docs held this view until the avalanche of evidence changed that attitude for most.

The negative effects, like muscle loss is certainly a problem, but it's no different than what would happen in any mismanaged weight loss program.

No, Diet and Exercise Are Not Better Than Drugs for Obesity

There’s no debate that diet and exercise aren’t more effective for people with obesity than antiobesity medications, contends Yoni Freedhoff, MD.

www.medscape.com

 

[Rakusa]

So semaglutide would eventually be the strongest anti-addiction drug of the popular 3, in case it's truly mediated by the speculated GLP-1 agonism. Note that the lower a Ki Value is, the higher its binding affinity.

Now imagine this scenario: GLP-1 agonists reduce both food and drug noise, is what what we would claim, given this threads shared knowledge. GLP-1 drugs = lower cravings. Now what if you still indulged in drugs or fast food ON semaglutide? Would you become desensitized to the anti addiction effects over time? It's harder, but possible. Because you actively work AGAINST the reduction in cravings. Could cravings return to HIGHER than baseline, after cessation of the drug? Whether that's drugs or fast food. Sort of like a rebound, where even agonizing of GLP-1 doesn't lead to lower cravings.

I think addiction research, when it comes to GLP-1, could be a super interesting topic in the next couple of years.

 

[TurboJet]

View attachment 310786

So semaglutide would eventually be the strongest anti-addiction drug of the popular 3, in case it's truly mediated by the speculated GLP-1 agonism. Note that the lower a Ki Value is, the higher its binding affinity.

Now imagine this scenario: GLP-1 agonists reduce both food and drug noise, is what what we would claim, given this threads shared knowledge. GLP-1 drugs = lower cravings. Now what if you still indulged in drugs or fast food ON semaglutide? Would you become desensitized to the anti addiction effects over time? It's harder, but possible. Because you actively work AGAINST the reduction in cravings. Could cravings return to HIGHER than baseline, after cessation of the drug? Whether that's drugs or fast food. Sort of like a rebound, where even agonizing of GLP-1 doesn't lead to lower cravings.

I think addiction research, when it comes to GLP-1, could be a super interesting topic in the next couple of years.

It's going to be interesting, lots of women take antidepressants and other drugs like paxil and whatever else their "DR" will prescribe them.

Will use of these other medications be reduced because they are healthier and happier or will it be secondary effects of wegovy ECT.