What's your current old man cycle?

Do you mean vitamin K2? I take the four version and the seven version. I did not know that there was any research that vitamin K can help with arterial plaque.

@ChaseIrons reversed his CAC score with huge K doses from 123 to 0 i think? Is that correct Chase?

He was taking 2 of these per day. Just notice the concentrations.

61aModfIu3L._AC_SY879_.jpg



 
Correct. There are some promising results.



I know this wasn't directed at me, but I'm managing LDL and ApoB super low hoping that I might see some reversal in calcified plaque. I've done a fairly extensive review of the literature and there's nothing conclusive with K2 or anything else.

I'll get another CAC mid next year and probably also a CT-A which will be out of pocket but will also give a better picture of endothelial health.
CAC only show hard plaque not soft plaque, correct?
 
I thought the studies on K2 are not conclusive.
Anyways, have you reversed any CAC?
Im not sure if I have any...when I get my body ultrasound yearly they never see any, but thats not indicative if theres any or not. Like I said, I need to get a CAC, APO-B and a lipoprotein A done soon.
 
Correct. There are some promising results.



I know this wasn't directed at me, but I'm managing LDL and ApoB super low hoping that I might see some reversal in calcified plaque. I've done a fairly extensive review of the literature and there's nothing conclusive with K2 or anything else.

I'll get another CAC mid next year and probably also a CT-A which will be out of pocket but will also give a better picture of endothelial health.
My arteries start to clog but according to my cardiologist, nothing's calcified yet.
So I try to get my LDL down (all my family has had high cholesterol but no CVD) also but unfortunately I get leg pain from the rosuvastatin (laughable 10 mg ED). Atorvastatin is next. I do take 200 mg coq10.

What are the state of the art supplements/drugs that are worth a shot?
Vitamin K and nattokinase?
I eat fairly healthy and upped my fiber intake.

Good luck with your scans please keep us updated.
 
@ChaseIrons reversed his CAC score with huge K doses from 123 to 0 i think? Is that correct Chase?

He was taking 2 of these per day. Just notice the concentrations.

61aModfIu3L._AC_SY879_.jpg




So doctors and researchers all over say that there are no known ways to lower the calcium score,
but
a Youtube guy who makes a living getting views and sponsors, says, hey, I lowered mine down to zero by taking THIS
 
What are the state of the art supplements/drugs that are worth a shot?
Vitamin K and nattokinase?
I eat fairly healthy and upped my fiber intake.

I wouldn't mess around with nattokinase. I mean it's fine, but the k2 and a statin will serve the same goal.

Psyllium husks and EPA/DHA are the supplements you should take.

For lipid management, you can get bempedoic acid from any of the Indian pharma vendors. Couple that with ezetimibe. The US version of that is "Nexletel" which is horrendously expensive, but cheap as beans if you can bring it in.

Repatha is an alternative but without any history of CVD and no obvious plaque, you'd be hard pressed to get a prescription. Do you know your ApoB?
 
I wouldn't mess around with nattokinase. I mean it's fine, but the k2 and a statin will serve the same goal.

Psyllium husks and EPA/DHA are the supplements you should take.

For lipid management, you can get bempedoic acid from any of the Indian pharma vendors. Couple that with ezetimibe. The US version of that is "Nexletel" which is horrendously expensive, but cheap as beans if you can bring it in.

Repatha is an alternative but without any history of CVD and no obvious plaque, you'd be hard pressed to get a prescription. Do you know your ApoB?
Even in India, nexlizet isn’t cheap. My calcium score was over 500, I take rosuvastatin and ezetimibe(Indian). I’d love to add nexlizet, gonna try to get a script from the endo next week. What’s the issue with nattokinase? It’s the only thing that’s kept my HCT on check. I’ll list my old man blast in a separate post.
 
I wouldn't mess around with nattokinase. I mean it's fine, but the k2 and a statin will serve the same goal.

Psyllium husks and EPA/DHA are the supplements you should take.

For lipid management, you can get bempedoic acid from any of the Indian pharma vendors. Couple that with ezetimibe. The US version of that is "Nexletel" which is horrendously expensive, but cheap as beans if you can bring it in.

Repatha is an alternative but without any history of CVD and no obvious plaque, you'd be hard pressed to get a prescription. Do you know your ApoB?
I hope I'll find a statin that won't paralyze my legs.
I doubt my health insurance would cover a pcsk9 inhibitor at this point.

I take psyllium husk daily, also flaxseed and chia seeds. Fish oil in days when I do not eat fatty fish which do 3 times a week.

I'll look up bempedoic acid. Thank you.

Unfortunately I do not know my apoB and can't find a lab that would measure it.
 
Vit K2 MK7. Shown to redistribute calcium build up to teeth and bones...
NATTOKINASE- 2000-4000 FU’S DAILY- reduces plaque GREATLY, prevents blood clots from occurring, lowers hematocrit slightly, increases HDL, lowers LDL, Trigs, and total cholesterol. REGRESSION OF PLAQUE IN BLOOD VESSELS BY UP TO 36%
Good to know. Interesting information. I need to read more about this.
 
CAC only show hard plaque not soft plaque, correct?

Correct. CT-A (CT angiogram) will show both.

Even in India, nexlizet isn’t cheap. My calcium score was over 500, I take rosuvastatin and ezetimibe(Indian). I’d love to add nexlizet, gonna try to get a script from the endo next week. What’s the issue with nattokinase? It’s the only thing that’s kept my HCT on check. I’ll list my old man blast in a separate post.

I’ll respond more fully, later, but in short, I’ve found bempedoic acid that’s cheaper than ezetimibe at one of the vendors here. Like $.30/day or some such.

Nattokinase is fine, just that I would consider other interventions first. It should theoretically reduce risk somewhat, but the research is limited.

Unlike niacin, for example which had a benefit to biomarkers but has no effect, or possibly an negative effect on outcomes.
 
Correct. CT-A (CT angiogram) will show both.



I’ll respond more fully, later, but in short, I’ve found bempedoic acid that’s cheaper than ezetimibe at one of the vendors here. Like $.30/day or some such.

Nattokinase is fine, just that I would consider other interventions first. It should theoretically reduce risk somewhat, but the research is limited.

Unlike niacin, for example which had a benefit to biomarkers but has no effect, or possibly a negative effect on outcomes.
Nattokinase, for me, is only about keeping HCT in check, as mine would wander up towards 55, even on TRT dosages. With Nattokinase, even on blasts, it wouldn’t go over 49. Love to see where I can get affordable nexlizet.
 
51, currently just 200mg test/week for the past 12 weeks. Next week I’ll blast 400 test/400 primo a week. Along with 6-9iu GH/day. Also take 10mg rosuvastatin, 5mg ezetimibe, 40mg telmisartan, 2.5mg nebivolol, 5mg cialis and 1000-2000mg metformin ED. BP last week was 119/71, RHR 70ish at around 270.
 
Love to see where I can get affordable nexlizet.


It's from HAB Pharma in India, a well respected manufacturer. The one with ezetimibe is "bempetol-ez" but I can't find it anywhwere, presently.

Do you guys know where a CT angiogram can be done for a decent price in the states?


Search for "CT angiography" near you. I'm finding it for less than $500.

I hope I'll find a statin that won't paralyze my legs.

I would only consider atorvastatin as a last resort. Maybe try a low dose of pravastatin. It is hydrophilic, i.e. doesn't cross the blood/brain barrier, like rosuvastatin, and it seems to have fewer adverse side effects. It's also less efficacious, but if it doesn't cause leg pain, that's a win.

Unfortunately I do not know my apoB and can't find a lab that would measure it.

This is the lipid panel I get and the place where I order it. They have the cheapest price I've found:


I doubt my health insurance would cover a pcsk9 inhibitor at this point.

If you can get an Rx, apply for a copay card:

I did and got approved, then discovered that my employer carries a special rider on their pharma benefit for a list of "preventative" meds that are hard to get. Hell of a deal for me.
 
So doctors and researchers all over say that there are no known ways to lower the calcium score,
but
a Youtube guy who makes a living getting views and sponsors, says, hey, I lowered mine down to zero by taking THIS

Exactly. You can search for his livestreams and see the history. His doctor sent the results and suggested him to try megadosing vitamin K (not a particular brand) and people from the livestream were suggesting him different brands while comparing the potencies.

That's what i remember since it goes a little back.. When he managed to reverse it he then said hey guys i used THAT product to lower it. I don't know if he's telling the truth or it was all a paid sponsorship and honestly i don't care much since i'm using another K supplement but with all that expensive and dangerous stuff we're already taking you think an experiment with megadosing K in an attempt to reverse CAC score won't worth it?
 
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