what's your gh dosaging?

[readalot]

So if my heart beats 70 bpm

that is 857 milliseconds

and I drive it up to 168 on cardio

that is 337 milliseconds

so . . . 520 milliseconds?

What am I missing?

You are a smart man. Most HRV monitoring on smart devices done at RHR AFAIK. Ain't going to look all the devices up. Must track using consistent approach.

Good review.

The effect of heart rate on the heart rate variability response to autonomic interventions - PMC

Heart rate variability (HRV), the beat-to-beat variation in either heart rate (HR) or heart period (R-R interval), has become a popular clinical and investigational tool to quantify cardiac autonomic regulation. However, it is not widely appreciated ...

pmc.ncbi.nlm.nih.gov

 

[Ghoul]

So if my heart beats 70 bpm

that is 857 milliseconds

and I drive it up to 168 on cardio

that is 337 milliseconds

so . . . 520 milliseconds?

What am I missing?

It's a complex calculation, of the various methods, root mean square of successive differences is the "simplest". lol

So much so there are companies that do nothing but write dedicated apps just for HRV.

Best Heart Rate Variability Monitor & App | Elite HRV

Heart Rate Variability (HRV) tracking app for deep insight into your health, stress, recovery and nervous system balance. Elite HRV's heart rate variability insights help you stay in tune with your body and on track toward your goals.

elitehrv.com

Here's a good synopsis of the topic.

What is Heart Rate Variability (HRV)? [The Ultimate HRV Guide]

Heart rate variability (HRV): What it is, why it's a sign of fitness, factors that affect it, how to improve it and use it to train smarter.

www.whoop.com

 

[malfeasance]

Sorry for being slow on the uptake, guys. This was a new concept for me. I appreciate your patient approach.

 

[Ghoul]

Sorry for being slow on the uptake, guys. This was a new concept for me. I appreciate your patient approach.

No worries. It's not really clearly explained in many places.

 

[MA11]

Stuff like that is where chatgpt shines.
Here's the answer to the prompt "ELI5: HRV"

HRV stands for Heart Rate Variability, which is a measure of the tiny differences in time between each heartbeat. Your heart doesn't beat like a metronome; instead, the time between beats changes a little, like 0.9 seconds, then 1 second, then 0.85 seconds.

Why is it important?
HRV tells you how well your body is handling stress. A high HRV usually means your body is relaxed and recovering well, while a low HRV might mean you're stressed, tired, or not fully recovered.

Think of it like this:

High HRV: Your nervous system is flexible and ready to handle challenges.
Low HRV: Your body might be overwhelmed or needs rest.
It's a tool often used in fitness and health to check if you're pushing too hard or need to take it easy.

Edit:
Using "ELI5" is underrated. Both in LLM and real life.

 

[athos1989]

I take 3ui in the morning on an empty stomach, and another 3ui before bed. I do it im. Do you think im or subc is better?

 

[Ghoul]

I take 3ui in the morning on an empty stomach, and another 3ui before bed. I do it im. Do you think im or subc is better?

If you can handle IM 2x / day, it's better.

 

[athos1989]

If you can handle IM 2x / day, it's better.

Thanks friend, I'll keep that in mind.

 

[MackVMT]

4IU max for me- split early morning and at night or 1 hour before workout and at night.

 

[MackVMT]

If you can handle IM 2x / day, it's better.

Ive seen it both ways. How much better is it IM according to what you have seen?

I pin enough stuff IM though so Id rather leave stuff like peptides and hgh as subc

 

[bigMoJo]

@malfeasance @songsofpyramids @Ghoul

 

[songsofpyramids]

I take 3ui in the morning on an empty stomach, and another 3ui before bed. I do it im. Do you think im or subc is better?

Im, for me, is much much better

How much better is it IM according to what you have seen?

Higher gh serum peak, which in my opinion just feels great honestly, and the impact on blood sugar is shorter lasting. I used to have a graph showing the difference but I think I’ve misplaced it.

 

[Ateam2023]

I take 3ui in the morning on an empty stomach, and another 3ui before bed. I do it im. Do you think im or subc is better?

it just gets in blood stream faster im injected

 

[athos1989]

According to what I have read, intramuscular GH is used and assimilated more.

 

[Ghoul]

Ive seen it both ways. How much better is it IM according to what you have seen?

I pin enough stuff IM though so Id rather leave stuff like peptides and hgh as subc

Subcutaneous injection is the route of administration that triggers the strongest immune reactions. Defenses have evolved in that area for obvious reasons. Since long term, immune reactions can result in an increasing loss of effectiveness, the more that's avoided the better.

IM has a much weaker immune response.

 

[MissedArmDay66]

I think that if you take reasonable precautions to minimize immunogenicity, ie don't recklessly hop on and off, avoid protocols wildly different from pharma, reconstitute to the correct dilution ratios, use pharma grade BAC, filter, and commit yourself to "continuous exposure" by staying on and just altering the dose as necessary, I think the incredible and growing list of health benefits far, far outweigh the risks.

I’m interested in your comment about correct dilution ratios as I’ve been running various peps for quite awhile including a 2.5mg maintenance dose of Tirz and not sure I’ve ever seen any data on what constitutes correct dilution ratio. I’ve searched around a bit but nothing definitive. If you have a link or something would appreciate it as the immunogenicity thing is something i wish i knew more about when I started using peps. Thanks in advance

 

[lilhawk]

I take 3ui in the morning on an empty stomach, and another 3ui before bed. I do it im. Do you think im or subc is better?

Subq is better. It's meant to be injected subq. Kurt Havens just had a podcast on about this as well and your absorbing far more GH when injected subq vs IM.

 

[songsofpyramids]

Subq is better. It's meant to be injected subq. Kurt Havens just had a podcast on about this as well and your absorbing far more GH when injected subq vs IM.

Not trying to start a big argument here but this information is not true. Medical researchers think im is better for a host of reasons (iv even better but dangerous for patients to do) but suggest subq because they have such low patient follow through with im protocols. Subq with hgh has much more protocol success and is suggested because of that more than anything else. People don’t like doing subq shots, and like im shots even less because they can hurt more. That’s why they’ve quested so hard for the once a week hgh injection, patients categorically suck at doing them regularly. Especially giving them to children. You could also argue you in fact “absorb” (not really what happens) more hgh with im shots as they push you gh serum higher and the mechanism of action is like 30 minutes less than subq. More bang for buck, especially if doing 2x a day. It also impacts blood glucose less drastically and less long injecting im.

 

[FuriousGrill]

Not trying to start a big argument here but this information is not true. Medical researchers think im is better for a host of reasons (iv even better but dangerous for patients to do) but suggest subq because they have such low patient follow through with im protocols. Subq with hgh has much more protocol success and is suggested because of that more than anything else. People don’t like doing subq shots, and like im shots even less because they can hurt more. That’s why they’ve quested so hard for the once a week hgh injection, patients categorically suck at doing them regularly. Especially giving them to children. You could also argue you in fact “absorb” (not really what happens) more hgh with im shots as they push you gh serum higher and the mechanism of action is like 30 minutes less than subq. More bang for buck, especially if doing 2x a day. It also impacts blood glucose less drastically and less long injecting im.

But are IM injections better for muscle building/lipolysis compared to SubQ? Do they offer a more lasting IGF one response? This is such a fascinating topic to me (one that I do not know much about).

 

[benfrankparkway]

I’m interested in your comment about correct dilution ratios as I’ve been running various peps for quite awhile including a 2.5mg maintenance dose of Tirz and not sure I’ve ever seen any data on what constitutes correct dilution ratio. I’ve searched around a bit but nothing definitive. If you have a link or something would appreciate it as the immunogenicity thing is something i wish i knew more about when I started using peps. Thanks in advance

Bump to this as well as it makes me wonder was I using proper dilution for peptides, GH. Also he mentioned filtering, which I never used before.