lankyOldIdiot
New Member
Greatly increases cardiovascular risk and there are extremely strong inverse correlations between basal insulin and lifespan. I recommend everyone read this paper:
Herman, M. E., O’Keefe, J. H., Bell, D. S. H., & Schwartz, S. S. (2017). Insulin Therapy Increases Cardiovascular Risk in Type 2 Diabetes. Progress in Cardiovascular Diseases, 60(3), 422–434. doi:10.1016/j.pcad.2017.09.001
Before the handwaving of "in T2D!" understanding the mechanisms, which I know just bores people, and the constraints on good studies in the bodybuilding population, do believe, there is reason to believe slin has an unfavorable risk-reward for most persons.
When used in combination with AAS and some other stuff, there are additional mechanisms that likely act in concert to increase morbidity risks (elevated triglycerides, endothelial dysfunction, etc.)
Do you have the full paper? Insulin Therapy Increases Cardiovascular Risk in Type 2 Diabetes - PubMed
How dangerous do you think slin is if:
- calories remain the same, at slight surplus for bulking
- user is very lean and insulin sensitive
- used only pre/post workout with rapid acting, like a Milos type protocol?