Wuhan Wansheng Biotechnology Co., Ltd. (USA, International)

What about things like KLOW / GLOW etc that are pre mixed?
I had horrible reaction site issues from KLOW blend. However, I can independently use each compound(kpv/ghkcu/tb500/bpc157) with no issues. I've read that ghk-cu shouldn't be mixed with anything as it can ruin other peptides bioavailability.


This site has a pretty cool tool they've built for referencing different peptides and if they can be mixed.
 
Tesa+secretagogue is uncharted territory, with all the risk that entails, in exchange for mediocre results compared to the well worn path of rHGH.
Coming up on 12 weeks 100mcg Ipa / 2mg Tesa 5x a week

I'm also on Reta, so to the degree it contributed to this result maybe we call it 50/50 at best. But I took Tesa specifically for visceral fat reduction. Dexa scan last week shows reduction from ~1.5 lbs of VAT to .75 lbs. I'll take a 50% VAT reduction as a win. Curious based on the FDA studies if discontinuing Tesa will bring VAT mass back to baseline, or if those findings had something to do with the limited lifestyle habits of HIV patients, vs my lifestyle of daily fasted cardio & weight training 6x a week.

Either way I think the risks of combining secretagogues is dose-dependent, and it seems the fitness community is sold on overdosing Ipamorelin to a concerning degree. This is perpetuated by the retailers who combine the two peptides so the Ipa dose is orders of magnitude larger than it should be.

The Huberman episode with Craig Koniver discusses proper Ipamorelin dosing to be in the range of 100mcg daily. People taking multiple milligrams to "feel" it are not doing themselves any favors. As pointed out in the above discussion, looking to side effects as a sign that a compound is working is not a valid or healthy pursuit when administering drugs. I mean, you all can do what you like, but I don't think doses in MG are serving the purpose you hope they are.
 
I had horrible reaction site issues from KLOW blend. However, I can independently use each compound(kpv/ghkcu/tb500/bpc157) with no issues. I've read that ghk-cu shouldn't be mixed with anything as it can ruin other peptides bioavailability.
I've seen this discussed, and what baffles me is...if that is true, how does a KLOW vial make it to Janoshik, get reconstituted and tested, and the test verifies proper quantities of each of the compounds? Do they stay intact only in quantity, but some reverse alchemy still violates the bioavailability despite the intact mass?
 
I've seen this discussed, and what baffles me is...if that is true, how does a KLOW vial make it to Janoshik, get reconstituted and tested, and the test verifies proper quantities of each of the compounds? Do they stay intact only in quantity, but some reverse alchemy still violates the bioavailability despite the intact mass?
Its been well worder that ghk-cu doesn't really mix well with almost any peptide. I guess that's why klow is starting to get a bad reputation.

On the other hand there's a handful of well tried premixes. Bpc + tb for example both peptides have the same ph level and from practice as they are getting popular almost no one is complaining from it as much.

But then there's the individual differences between all of us. Peptides are no different than aas in the realm of different people have different reactions to them.
 
Coming up on 12 weeks 100mcg Ipa / 2mg Tesa 5x a week

I'm also on Reta, so to the degree it contributed to this result maybe we call it 50/50 at best. But I took Tesa specifically for visceral fat reduction. Dexa scan last week shows reduction from ~1.5 lbs of VAT to .75 lbs. I'll take a 50% VAT reduction as a win. Curious based on the FDA studies if discontinuing Tesa will bring VAT mass back to baseline, or if those findings had something to do with the limited lifestyle habits of HIV patients, vs my lifestyle of daily fasted cardio & weight training 6x a week.

Either way I think the risks of combining secretagogues is dose-dependent, and it seems the fitness community is sold on overdosing Ipamorelin to a concerning degree. This is perpetuated by the retailers who combine the two peptides so the Ipa dose is orders of magnitude larger than it should be.

The Huberman episode with Craig Koniver discusses proper Ipamorelin dosing to be in the range of 100mcg daily. People taking multiple milligrams to "feel" it are not doing themselves any favors. As pointed out in the above discussion, looking to side effects as a sign that a compound is working is not a valid or healthy pursuit when administering drugs. I mean, you all can do what you like, but I don't think doses in MG are serving the purpose you hope they are.
Would you consider moving on to gh from the tesa ipa combo?
 
Would you consider moving on to gh from the tesa ipa combo?
That is part of the plan. Going to start TRT early next year. Want to give that some time on its own, then will add some sprinkles on top down the road, including GH, which I've already amassed a fair amount of in preparation.
 
Coming up on 12 weeks 100mcg Ipa / 2mg Tesa 5x a week

I'm also on Reta, so to the degree it contributed to this result maybe we call it 50/50 at best. But I took Tesa specifically for visceral fat reduction. Dexa scan last week shows reduction from ~1.5 lbs of VAT to .75 lbs. I'll take a 50% VAT reduction as a win. Curious based on the FDA studies if discontinuing Tesa will bring VAT mass back to baseline, or if those findings had something to do with the limited lifestyle habits of HIV patients, vs my lifestyle of daily fasted cardio & weight training 6x a week.

Either way I think the risks of combining secretagogues is dose-dependent, and it seems the fitness community is sold on overdosing Ipamorelin to a concerning degree. This is perpetuated by the retailers who combine the two peptides so the Ipa dose is orders of magnitude larger than it should be.

The Huberman episode with Craig Koniver discusses proper Ipamorelin dosing to be in the range of 100mcg daily. People taking multiple milligrams to "feel" it are not doing themselves any favors. As pointed out in the above discussion, looking to side effects as a sign that a compound is working is not a valid or healthy pursuit when administering drugs. I mean, you all can do what you like, but I don't think doses in MG are serving the purpose you hope they are.

Unfortunately the predisposition to accumulate visceral fat, “central adiposity” is mostly regulated by growth hormone.

Keeping weight off will delay any reaccumulation, but unless you stay in perpetual perfect caloric balance or a deficit, in the normal cycle of your endogenous GH pulses triggering free fatty acids release from fat cells, any that go unused, regardless of where they come from (ie subQ if you already got rid of most visceral), they’ll preferentially redeposit in visceral fat.

Age, a lifetime of insulin and cortisol exposure has essentially broken the “in door” on visceral fat cells, so it’s stuck open, allowing free fatty acids to easily enter and accumulate, while the out door is rusted shut. It’s only elevated, youthful levels of GH that “force open” the ‘out door’ of visceral fat cells.

Raising GH by exogenous compounds doesn’t fix the doors. It just temporarily opens the out door wider than the in door, so FFAs are more likely to exit the visceral fat cells than enter and accumulate. Once GH levels return to what they were previously, it all goes back to the previous state.

The evolutionary reason for this is probably that as an animal, with age, physical decline meant the ability to acquire calories declined, and accumulating fat when excess food is available, storing it in the stubborn visceral deposit which only releases under conditions of absolute starvation, enhanced survival. Younger humans preferentially store fat in easier to release deposits, to meet the energy needs of high physical activity.
 
Unfortunately the predisposition to accumulate visceral fat, “central adiposity” is mostly regulated by growth hormone.

Keeping weight off will delay any reaccumulation, but unless you stay in perpetual perfect caloric balance or a deficit, in the normal cycle of your endogenous GH pulses triggering free fatty acids release from fat cells, any that go unused, regardless of where they come from (ie subQ if you already got rid of most visceral), they’ll preferentially redeposit in visceral fat.

Fascinating thank you for the explanation. Looks like I'll be cycling through both GH and secretagogues on a regular basis (in addition to cutting cycles) to keep VAT in check.
 
Hence my question. If it doesn't mix well, why do KLOW tests show the separate peptides still intact?

Sorry, what tests show this? No simple HPLC test can detect determine peptide interactions.

There are NO multi-peptide pharma drugs. Cagri-Sema would be the first if its approved, and requires careful formulation and use of specific excipients that prevent them from interacting in solution.
 
Sorry, what tests show this? No simple HPLC test can detect determine peptide interactions.

There are NO multi-peptide pharma drugs. Cagri-Sema would be the first if its approved, and requires careful formulation and use of specific excipients that prevent them from interacting in solution.
The reason cagri sema is a difficult one to formulate is because both are stable at different pH’s. Not because they interact with each other.
 
Sorry, what tests show this? No simple HPLC test can detect determine peptide interactions.

There are NO multi-peptide pharma drugs. Cagri-Sema would be the first if its approved, and requires careful formulation and use of specific excipients that prevent them from interacting in solution.

My only claim is that the tests show the mass of each separate peptide. So if the mass of each is still detected, what indicates their denaturing, or the lack of bioavailability, or the lack of effectiveness?






 
My only claim is that the tests show the mass of each separate peptide. So if the mass of each is still detected, what indicates their denaturing, or the lack of bioavailability, or the lack of effectiveness?






They react inside your body not in the vial my man. Hence jano test shows the contents and has absolutely nothing to do whith what that/those compounds will do to an individual.
 
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