Zero libido, low T (21, male)

[lxm]

Do u workout. You should exercise. The weight gain. This could be bloat. Arimidex will help with that. You can control some of this or a lot of it with proper nutrition and regular exercise. Put some sweat into it. Don't depend on your doc for everything. Take it into your own hands if need be. But whatever you do research it. Look on here about arimidex or google it and read and research how others use it. Come up with a game plan and do it. This is your health dude. Take control of it. Get lots of rest. Eat right. Do everything you can to control your health.

I use test cyp every 4 days. Works great for me. I also use 12.5 mgs arimidex every other day. I was taking arimidex ed and had joint issues. I found my spot and adjust as needed. I don't depend on docs to control it anymore. Hell yesterday I had a doc appointment and they told me that the test caused me to have a bundle blockage.

I carry out compound lifts x4 a week eating 2300cals of high protein, medium fats, low carbs, along with cardio and make zero gains or improvements in body composition.

I'm going to look into the arimidex, thank you for the suggestion. Finally any points of information I should bring up with the consultant when I see him for a second opinion?

Has

Klinefelter syndrome - Wikipedia, the free encyclopedia

Been ruled out?

I had a chromosome test which ruled out XXY. My endocrinologist was pretty certain I would come back as a mosaic because my history tied in so well with the overall picture of XXY males.

 

[domino]

I'm going to look into the arimidex, thank you for the suggestion. Finally any points of information I should bring up with the consultant when I see him for a second opinion?

I guess the only thing I would bring up to the consultant is why haven't you guys tried to control my estrogen? Im not a doctor but I would be asking this for sure. Why don't we try to get my estrogen in check before we even started Testosterone? Maybe - maybe if they would have tried like clomid on you first - it might have brought your test levels up. I would really push them for an AI - if not then I would get it on my own.

 

[Kaynon]

I had thyroid done, all values came back perfectly normal.

Post actual lab values with ranges. What do you mean by "perfectly normal"? Lab data ranges are for disease detection. Normal lab data doesn't correlate to optimal quality of life.

 

[zkt]

As a mosaic you likely have some female biochemical processes predominating. Long term E and PRL control is probably indicated. The treatments might be problematic. You may also metabolize T more rapidly than the average guy. So higher dose may be required.
You are definitely in need of a doctor who is up to speed on all this or you need to become very well informed yourself and convince the average doc of that and lead the way yourself with his cooperation.

http://47xxy.com/Sitedocs/DR_ROLLA_LETTER.PDF

 

[UK86]

As a mosaic you likely have some female biochemical processes predominating. Long term E and PRL control is probably indicated. The treatments might be problematic. You may also metabolize T more rapidly than the average guy. So higher dose may be required.
You are definitely in need of a doctor who is up to speed on all this or you need to become very well informed yourself and convince the average doc of that and lead the way yourself with his cooperation.

http://47xxy.com/Sitedocs/DR_ROLLA_LETTER.PDF

His test ruled out XXY?

 

[lxm]

As a mosaic you likely have some female biochemical processes predominating. Long term E and PRL control is probably indicated. The treatments might be problematic. You may also metabolize T more rapidly than the average guy. So higher dose may be required.
You are definitely in need of a doctor who is up to speed on all this or you need to become very well informed yourself and convince the average doc of that and lead the way yourself with his cooperation.

http://47xxy.com/Sitedocs/DR_ROLLA_LETTER.PDF

Sorry, my chromosome test can back as a 'normal' XY male.... my question is could this genetic test have missed out a mosaic streak?

The endocrinologist (Junior diabetes registrar) who I am under seems to think that all males are the same, testosterone is testosterone and works identically in the same way with every patient. He believes that all cases are as simple as receiving testosterone and the patient should be fine, that nothing else comes into play. I strongly feel that my case is not as simple as prescribing testosterone, I genuinely feel that there are other parameters that need to be looked at and considered.

 

[lxm]

Sorry I forgot to add to the above (cant edit post) that I still don't feel right on the treatment im receiving (125mg sustanon250 per week)

During each new injection cycle period of 14 days there are little things that I notice happening, this brings me to the above conclusion that my case is not as standard as the doctor seems to make out.

first 3 days after injection = headaches, extremely red 'sunburnt' face, extremely emotional.

first 7 days after injection = no morning or nocturnal erections, no sporadic erections, erections only if they are 'forced' and erection quality at 60% blood flow?(after the 7 day marker erection quality returns to normal along with morning & nocturnal wood every day.

first 10 days after injection = unable to orgasm, when I do ejaculate and climax, there is a 'blunt' & 'muffled' feeling with little to no pleasure.... the last few days before my next injection I can have 'ok' orgasms but nothing like I used to.

Also below as posted previously by trough blood work of 1ml sustanon250 injected at one time over 4 weeks, 3 weeks & 2 weeks

4 week injection (62.5mg per week) trough @ 7.8nmol
3 week injection (83.3mg per week) trough@ 7.6nmol
2 week injection (125mg per week) trough @ 10.6nmol

Both week 3 & 4 test levels show that my own natural production is still holding @ 7nmol after the sustanon has been completely metabolized

week 2 test levels show a trough of 10nmol @ 125mg per week....

it does seem that my body is metabolizing quickly....? Ive seen other guys with trough levels @ 100mg per week way higher.

Help!

 

[lxm]

My doctor was taken me off testosterone due to non response for the time being and wants my own system to re-start. He states that this should take 3 months and its without the aid or help of HCG.

During my TRT I took a semen analysis, this has come back as zero sperm which wasn't a surprise whilst being on TRT. This is another reason my doctor wants me off T, so we can get a baseline semen count once I have recovered.

He has ordered DNA tests for the sequency of androgen recptors - (potential androgen insensitivity)


Overall the doctor would rather have me off T if I am feeling no better with therapy, so that my own production is active and for fertility reasons until we get to the bottom of this (hopefuly) Also a bone density test has been ordered to see if my body has a negative effect of being low on testosterone along with a dexamethasone suppression test.

Its going to be a rough 12 weeks im guessing....
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[lxm]

An update for everyone, It took me 5 months for my HTPA to fully recover (Feb 14)

Feb 2014 bloods ;

Test 8.7nmol (8.6-28.8 )
E2 156pmol (40-150)
SHBG 12nmol (18-45)


Doctor now has a baseline of bloods for April 2014(Test, E2, SHGB etc) and a sperm baseline. I am awaiting a copy of these. I had a sleep assessment to rule out any conditions which came back negative, also a pelvic and abdomen CT scan, along with DEXA. These all came back negative.

I have lost 10kg since my last consultation and he was obviously impressed, but symptoms still linger. He offered me TRT again but I expressed my concern for relying on TRT longterm (im 22) and brought A.I monotherapy, HCG & CLOMID therapy to the table.

He looked into the above and has agreed to put me on an initial 4 month period of AI (arimidex) and see where it puts me. This is purely experimental and 'off label' and I am to be one of small few NHS male patients to have received this treatment within the UK.

I will keep updated my baseline bloods, and my 4 month 'A.I' bloods.

 

[lxm]

I got the second set of results back since stopping TRT. My doctor is taking these as 'baseline' for the AI monotherapy. I am surprised at the results, first time my SHBG has been above 12 in the last 3 years.

April 2014
Test:13.9 (8.6-28)
E2 :72 (40-150)
SHBG: 18 (18-45)
LH : 4 (1-8)
FSH : 12 (1-8)


Feb 2014 bloods ;
Test 8.7nmol (8.6-28.8 )
E2 156pmol (40-150)
SHBG 12nmol (18-45)

 

[lxm]

AI monotherapy has been a godsend for me! 85% of symptoms relieved...

Ive only been taking Anastrzole for 16 days, but what a difference.

 

[blazinshotguns]

^ nice once you stop taking that AI the rebound estrogen will blow .

Anyway can anyone tell me what vitamin D does because my levels are very low and so was my natural t

 

[James23]

AI monotherapy has been a godsend for me! 85% of symptoms relieved...

Ive only been taking Anastrzole for 16 days, but what a difference.

See.

 

[LW64]

Anyway can anyone tell me what vitamin D does because my levels are very low and so was my natural t

Vitamin D was mischaracterized when it was discovered. It isn't a vitamin. It's a hormone.

Deficiency has been implicated in a list of health problems/diseases that is about a mile long. You need to supplement. Start with 5,000 IUs D3 once a day (get gel-caps, they are absorbed better than powders). Get labs for D level (25[OH]D) at 3 months and adjust your dose to aim for a serum level in the 50s - units are ng/mL.

 

[LW64]

AI monotherapy has been a godsend for me! 85% of symptoms relieved...

Ive only been taking Anastrzole for 16 days, but what a difference.

What is your AI dose?

 

[lxm]

^ nice once you stop taking that AI the rebound estrogen will blow .

I'm trying to shift as much fat as possible whilst on the AI, so when I do come off I'm in the best position possible for my hormone ratio.

See.

What is your AI dose?

I take 1mg eod

 

[Britman]

lxm

What is your Total T now after use of AI?

Also what was result of your sperm test as you looks like your FSH is on the high side?

 

[foreveryoung]

16 days is way too early to consider something a "godsend", but hopefully you get long term success one way or another

 

[LW64]

I'm trying to shift as much fat as possible whilst on the AI, so when I do come off I'm in the best position possible for my hormone ratio.

Try a low-carb, high fat diet.

 

[Paul_Johnson]

Try a low-carb, high fat diet.

my thoughts exactly.