Cardarine sides?

[Jet Labs]

I'm thinking of trying Cardarine for fat burning properties, but before I order it has anyone got any serious sides from it like heart palpitations or increase in bp? I'd be running 10mg/ed btw along with 2iu hgh and test/mast/var.

Thanks for any feedback.

 

[Cashton]

I'm thinking of trying Cardarine for fat burning properties, but before I order it has anyone got any serious sides from it like heart palpitations or increase in bp? I'd be running 10mg/ed btw along with 2iu hgh and test/mast/var.

Thanks for any feedback.

I wouldn’t run it, but that’s just me, I’ll bet you can lose the fat just as easy without Cardarine.

 

[Jet Labs]

I wouldn’t run it, but that’s just me, I’ll bet you can lose the fat just as easy without Cardarine.

Why not?

 

[Cashton]

Why not?

Because losing fat isn’t hard, also take it for what it’s worth (not much) but one study on rats they used (which were genetically fucked already and would likely get cancer as it was) but every single rat ended up with cancer tumours if I recall correctly, either way, take a little ephedrine and and a cup of coffee, go for a jog and eat a little less if you really need a boost to lose weight, no need to add in drugs that we really don’t know exactly what they do yet for such a simple purpose.

 

[BeefNewton]

I ran it for quite a while and never had any major issues, but I swear I had a lot of skin tags show up while on it. I've also heard others talk about them (skin tags). The positive effects on my cardio also didn't last, and even after taking myself off a while, I was never able to get them back. Look up GW0742, which is somewhat of a successor to Cardarine, but there is even less information about it. Probably just makes bigger tumors. But I have some on the way anyway and am totally willing to guinea pig myself out.

 

[Jet Labs]

Because losing fat isn’t hard, also take it for what it’s worth (not much) but one study on rats they used (which were genetically fucked already and would likely get cancer as it was) but every single rat ended up with cancer tumours if I recall correctly, either way, take a little ephedrine and and a cup of coffee, go for a jog and eat a little less if you really need a boost to lose weight, no need to add in drugs that we really don’t know exactly what they do yet for such a simple purpose.

The cancer aspect i know about, but they gave the rats/mice they used 50x the regular dose and that's equivalent to humans taking 5-10 grams of the stuff daily so not really good science. Besides 50x the normal amount of anything will damn near kill you even water. You get me on this?

As for just adjusting diet and working harder I feel you on that brother, guess I'm just looking too burn the fat off a little faster thus PEDS, but do you never say add an extra compound or up dosage to move the scale along a little faster?

Cheers brother.

 

[Cashton]

The cancer aspect i know about, but they gave the rats/mice they used 50x the regular dose and that's equivalent to humans taking 5-10 grams of the stuff daily so not really good science. Besides 50x the normal amount of anything will damn near kill you even water. You get me on this?

As for just adjusting diet and working harder I feel you on that brother, guess I'm just looking too burn the fat off a little faster thus PEDS, but do you never say add an extra compound or up dosage to move the scale along a little faster?

Cheers brother.

Water wont give you cancer though... either way the study was full of flaws for lack of a better word, but I still don’t wanna fuck with a drug that COULD Have side effects that include ... CANCER to lose a couple points of body fat %. Again, just my opinion..


edit: honestly no I don’t, I take caffeine if I want an extra boost, I plan out a cycle and I stick too it, but if I were to add somthing for an extra boost, it wouldn’t be something that hasn’t been studied well, or something that proved cancerous even in a flawed rodent model, there’s just so many other drugs out there.. I was looking into one of those myostatin inhibitors, ACE somthing I believe, one of the side effects during the trail was bleeding from the ears and eyes if I recall correctly.. don’t know if it was dose dependant or how it occurred but just because it could give me a great size increase doesn’t mean I’m gonna use somthing that could make me bleed from my ears and or eyes.

 

[Jet Labs]

Water wont give you cancer though... either way the study was full of flaws for lack of a better word, but I still don’t wanna fuck with a drug that COULD Have side effects that include ... CANCER to lose a couple points of body fat %. Again, just my opinion..


edit: honestly no I don’t, I take caffeine if I want an extra boost, I plan out a cycle and I stick too it, but if I were to add somthing for an extra boost, it wouldn’t be something that hasn’t been studied well, or something that proved cancerous even in a flawed rodent model, there’s just so many other drugs out there.. I was looking into one of those myostatin inhibitors, ACE somthing I believe, one of the side effects during the trail was bleeding from the ears and eyes if I recall correctly.. don’t know if it was dose dependant or how it occurred but just because it could give me a great size increase doesn’t mean I’m gonna use somthing that could make me bleed from my ears and or eyes.

Fair enough.

 

[eery]

I've had no sides at 10-20mg a day over 6months except better cardio.

I don't think it does anything for fatloss except helping you with better cardiovascular fitness

 

[MFAAS]

The cancer aspect i know about, but they gave the rats/mice they used 50x the regular dose and that's equivalent to humans taking 5-10 grams of the stuff daily so not really good science. Besides 50x the normal amount of anything will damn near kill you even water. You get me on this?

As for just adjusting diet and working harder I feel you on that brother, guess I'm just looking too burn the fat off a little faster thus PEDS, but do you never say add an extra compound or up dosage to move the scale along a little faster?

Cheers brother.

Not true. The actual dose conversion ends up being barely higher than the therapeutic dose. I wouldn't touch cardarine with a 10 foot pole!


View: https://www.reddit.com/r/PEDsR/comments/815ixw/cardarine_cancer/?utm_medium=android_app&utm_source=share


Does this mean it will cause cancer? No. I don't know. But it certainly doesn't seem to be worth the risk to me. There is quite a large data set around PPAR delta associated agonist association with cancer and tumor growth. SO MANY people in the PEDs community just spout the same old crap to justify and reinforce their own bias that cardarine is "safe"... because they want to use it to make up for the fact that they never learned the discipline to cut properly. Losing fat isn't that hard. Like the other person said, take a little ephedrine and just cut calories to lose a sustainable amount of weight.

 

[MFAAS]

Also, the downside of the enhanced cardio effects of cardarine is that it will prevent cardio adaptations to your baseline, so long term you're getting less benefit from angogenesis than if you were to just do normal cardio and increase your endurance that way.

 

[Jet Labs]

Good info brother, thanks. Guess i was reading old studies

 

[BeefNewton]

Also, the downside of the enhanced cardio effects of cardarine is that it will prevent cardio adaptations to your baseline, so long term you're getting less benefit from angogenesis than if you were to just do normal cardio and increase your endurance that way.

I always wondered about this, as well as other substances like ITPP.

 

[Aftermath9716]

Rats are genetically predisposed to a high incidence of tumors and cancers, such a shame we don't use moneys for tests.

Someone on reddit post this

Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) ligands do not potentiate growth of human cancer cell lines

Abstract. Ligands for peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) increase skeletal muscle fatty acid catabolism, improve insulin sensitivity,

academic.oup.com

GW501516 and GW0742 do not increase growth of human cancer cell lines​

but meh I don't really understand it.

here's a more recent one

PPARβ/δ a potential target in pulmonary hypertension blighted by cancer risk - PMC

www.ncbi.nlm.nih.gov

"Of particular relevance are two abstracts from GSK showing that GW501516 causes cancer in rats6 and mice7 after 104 weeks of dosing."

I wouldn't run it that long though lol

"The precise role of PPARβ/δ in cancer, particularly in humans, however, remains unclear as reports continue to emerge showing that agonists may either increase or protect against different cancers."

In conclusion who fucking knows

I run it only on blast since my family is not predisposed to cancer.

 

[MFAAS]

I always wondered about this, as well as other substances like ITPP.

Yeah it seems to be the case, since your blood becomes more efficient as is, it reduces the need for adaption, and thus you don't adapt. You're better off just doing cardio and getting at it the old fashion way

 

[BeefNewton]

I actually posted a question about this on another board and never got an answer. Exact same topic. I asked that since the body is only ever coaxed into getting stronger when forced to adapt to stress, does removing the stress, even partially, prevent that from happening? It's actually good that ITPP is impossible to get now, because that stuff was really addictive in how well it worked. Nowadays, I only plan on using stuff like this pre-fuck.

 

[Cashton]

I actually posted a question about this on another board and never got an answer. Exact same topic. I asked that since the body is only ever coaxed into getting stronger when forced to adapt to stress, does removing the stress, even partially, prevent that from happening? It's actually good that ITPP is impossible to get now, because that stuff was really addictive in how well it worked. Nowadays, I only plan on using stuff like this pre-fuck.

Not impossible or even hard to get I don’t think, maybe depends where your from?

 

[grey]

No sides for me (besides PIP), but i keep the dose reasonable.

 

[muscletrain]

Rats are genetically predisposed to a high incidence of tumors and cancers, such a shame we don't use moneys for tests.

Someone on reddit post this

Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) ligands do not potentiate growth of human cancer cell lines

Abstract. Ligands for peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) increase skeletal muscle fatty acid catabolism, improve insulin sensitivity,

academic.oup.com

GW501516 and GW0742 do not increase growth of human cancer cell lines​

but meh I don't really understand it.

here's a more recent one

PPARβ/δ a potential target in pulmonary hypertension blighted by cancer risk - PMC

www.ncbi.nlm.nih.gov

"Of particular relevance are two abstracts from GSK showing that GW501516 causes cancer in rats6 and mice7 after 104 weeks of dosing."

I wouldn't run it that long though lol

"The precise role of PPARβ/δ in cancer, particularly in humans, however, remains unclear as reports continue to emerge showing that agonists may either increase or protect against different cancers."

In conclusion who fucking knows

I run it only on blast since my family is not predisposed to cancer.

It was considered almost a miracle med with the benefits, even if the rats they use (I forgot the name of them) are bread specifically for cancer, the fact that the dose used by humans is actually a lot closer to the rat dose (the dosing conversion going around on forums was way off) *and* GSK shelved it makes me say no fucking way.

A multi billion dollar corp. would not shelve a drug with these benefits for no good reason. I mean it was a boon in so many areas it's great for lipid protection, cardio, it had a laundry list of benefits.

I wish this shit was approved I don't have the balls to run it. It also great on cycle with orals to keep lipids in check with something like Anavar.

Glaxo doesn't walk away from shit like this.

 

[nukklehead]

I felt better cardio wise on it but not significant fat loss. Also may have felt a little tired at times and MAYBE a slight drop in libido ( was on 400 mg T at the time which is my blast, cruise at 175 mg) but this is all anecdotal. I felt maybe with reason why Glaxo may have shelved because it was possible it would replace 2 or 3 different drugs (statins etc) at one time which could lead to a devastating financial loss to big pharm if the supposed effects of it are true. Remember, pharma makes money off of sickness, not wellness.