Filtering finished oils

[verylargeshoes]

Is there harm in using PTFE for water-based

I don't know firsthand -- I took exactly 1 chemistry class in college -- and I do hope one of the many less dangerously ignorant people in this thread will comment.

It would maybe work in a pinch, as long as it's a hydrophilic membrane. I have read that PTFE is naturally hydrophobic so they have to coat it to be hydrophilic, whereas PES is naturally hydrophilic. PTFE also apparently exhibits higher protein binding than PES, so PES would definitely be better for protein based APIs.

My good buddy Claude.AI says the following, but keep in mind that I have to correct just about every AI on some deeply astounding errors in about 2-5% of the responses it gives. And those are just the errors I'm actually able to identify. The other day Claude based an entire page-long response regarding PIP around the premise that a 200mg/mL solution was less concentrated than a 100mg/mL solution.

Yes, you can use hydrophilic PTFE filters for water-based peptide/HGH solutions, and they work well for this application.

Hydrophilic PTFE for Peptides​

Advantages:

• Low protein binding - PTFE is relatively inert to proteins
• Excellent chemical resistance - Superior to most other membranes
• Compatible with BAC water - Benzyl alcohol won't affect PTFE
• Good flow rates once wetted properly
• Broad pH compatibility - Works across wide pH range

Performance Considerations:

• Wetting: Requires proper priming with aqueous solution (may need gentle pressure initially)
• Protein recovery: Generally good, though PES may have slightly lower binding
• Durability: Very chemically stable, won't degrade

PES vs Hydrophilic PTFE for Peptides​

PES remains the gold standard because:

• Naturally hydrophilic (easier wetting)
• Extensively characterized for protein applications
• Slightly lower protein binding in some studies
• More consistent batch-to-batch performance

Hydrophilic PTFE is excellent when:

• You need maximum chemical resistance
• Working with challenging pH conditions
• PES filters aren't readily available
• You're filtering multiple different solution types

Bottom Line​

Hydrophilic PTFE filters will work very well for peptides/HGH in BAC water. While PES might have a slight edge in protein recovery, the difference is typically minimal for most applications. Choose based on availability and your specific needs.

Both are far superior to nylon or PVDF for peptide applications.

 

[verylargeshoes]

Literal mental illness, plain and simple. I saw this thread and was like what the actual fuck...

Raws in *this* economy?!?

Man, I have all the equipment and consumables ready to go, and all the raws I can find is stuff somebody spilled and swept off the lab floor, or raws for shit nobody needs, like estradiol valerate, or priced way higher per gram than finished products from good sources. My mental illness has nothing to do with it.

And yeah, I might even pay a small premium for high purity raws so I can ensure the finished product isn't mixed in somebody's grimy bathtub with hints of biker crank, but even sources with more buying power are getting raws at < 85% purity (see recent Neoanabolics post regarding Anadrol).

If you have a good raws supplier still shipping, hook a brother up. But if you tell me that you were smart enough to stock up before all this tariff/crackdown stuff started, I will use my very special set of Liam Neeson skills, and I will find you, and I will sucker punch you in right in the dick.

 

[verylargeshoes]

KS-TEK has some, but probably better to just go the AliExpress route or get it from their website directly.

Their website looks decent. I got this message from them for my AliX order, btw. So use Fedex or USPS when shipping to the US if that's an option.

DHL shipping requires additional customs duties and requires applying for a whitelist with customs. Can we use a logistics service with the same delivery time? For example, FedEx or USPS?

 

[Photon]

Their website looks decent. I got this message from them for my AliX order, btw. So use Fedex or USPS when shipping to the US if that's an option.

The website has a wider selection than Amazon but AliExpress has the widest selection and lowest prices. I ordered from the website once before thinking it might be faster but it ended up coming from China using USPS.

I've never had them message me before on AliX tho. It always comes by USPS.

If there's lab equipment you're looking for and you cant find it, you can send him a message and he will try and source it for you. He's good to work with, replies really quick.

 

[narta]

But if you tell me that you were smart enough to stock up before all this tariff/crackdown stuff started, I will use my very special set of Liam Neeson skills, and I will find you, and I will sucker punch you in right in the dick.

 

[Pupil B]

Raws in *this* economy?!?

Man, I have all the equipment and consumables ready to go, and all the raws I can find is stuff somebody spilled and swept off the lab floor, or raws for shit nobody needs, like estradiol valerate, or priced way higher per gram than finished products from good sources. My mental illness has nothing to do with it.

And yeah, I might even pay a small premium for high purity raws so I can ensure the finished product isn't mixed in somebody's grimy bathtub with hints of biker crank, but even sources with more buying power are getting raws at < 85% purity (see recent Neoanabolics post regarding Anadrol).

If you have a good raws supplier still shipping, hook a brother up. But if you tell me that you were smart enough to stock up before all this tariff/crackdown stuff started, I will use my very special set of Liam Neeson skills, and I will find you, and I will sucker punch you in right in the dick.

I know multiple sources for raws that have mast tren primo etc rn, albeit inflated prices but still not bad. Paid a little under $8 a gram for mast e and tren e. I got mine about 2 months ago my friends made orders in the past week.

If I asked for a source here the mentally not-so-well OCDers, who do shit like filter finished oils and spend hundreds of dollars testing if established sources who've been around for years scammed them on a vial that contains $1 of test raws that they sell for $30-50+, would talk about spoon feeding and tell me to fuck myself, so no, nice try though.

 

[verylargeshoes]

I know multiple sources for raws that have mast tren primo etc rn, albeit inflated prices but still not bad. Paid a little under $8 a gram for mast e and tren e. I got mine about 2 months ago my friends made orders in the past week.

If I asked for a source here the mentally not-so-well OCDers, who do shit like filter finished oils and spend hundreds of dollars testing if established sources who've been around for years scammed them on a vial that contains $1 of test raws that they sell for $30-50+, would talk about spoon feeding and tell me to fuck myself, so no, nice try though.

Yes but if you DM me a source, they’d never know. Come on, commit the perfect crime and get away with it. Do it out of spite for those motherfuckers.

 

[Ateam2023]

I know multiple sources for raws that have mast tren primo etc rn, albeit inflated prices but still not bad. Paid a little under $8 a gram for mast e and tren e. I got mine about 2 months ago my friends made orders in the past week.

If I asked for a source here the mentally not-so-well OCDers, who do shit like filter finished oils and spend hundreds of dollars testing if established sources who've been around for years scammed them on a vial that contains $1 of test raws that they sell for $30-50+, would talk about spoon feeding and tell me to fuck myself, so no, nice try though.

 

[TheDieselZ]

I noticed a huge difference in PIP before and after filtering some finished oil I got. I used a PES .2 filter even though they’re for peptides. Oh well. It made a difference.

I used to brew my own stuff many years ago and never had any pip from it. I theorize these bigger labs skip steps in the filtering process to speed up production volume.

 

[Kralteramon]

I noticed a huge difference in PIP before and after filtering some finished oil I got. I used a PES .2 filter even though they’re for peptides. Oh well. It made a difference.

I used to brew my own stuff many years ago and never had any pip from it. I theorize these bigger labs skip steps in the filtering process to speed up production volume.

It's just that you don't want dissolved filter membrane in your oils, even if it's PIP free. I would use PTFE from now on.

 

[TheDieselZ]

It's just that you don't want dissolved filter membrane in your oils, even if it's PIP free. I would use PTFE from now on.

Got a good online source? I used these.

Amazon.com

 

[Photon]

Got a good online source? I used these.

Amazon.com

KS-Tek.
They have some stuff on Amazon, else from their website, else from AliExpress. AliExpress cheapest, most variety. Amazon most expensive, least variety.

Don't want China?
Tisch

Tisch Scientific Filter Syringe .22μm PTFE 25mm - Sterile Individually

Tisch Scientific Filter Syringe 22μm Ptfe 25mm – Peptide Test Lab Supplies - Fast, accurate, and trusted.

peptidetest.com

 

[verylargeshoes]

Don't want China?
Tisch

Zoom in…enhance…”it says Made in China”

 

[Photon]

Zoom in…enhance…”it says Made in China”

Looks like China it is!

 

[TheDieselZ]

KS-Tek.
They have some stuff on Amazon, else from their website, else from AliExpress. AliExpress cheapest, most variety. Amazon most expensive, least variety.

Don't want China?
Tisch

Tisch Scientific Filter Syringe .22μm PTFE 25mm - Sterile Individually

Tisch Scientific Filter Syringe 22μm Ptfe 25mm – Peptide Test Lab Supplies - Fast, accurate, and trusted.

peptidetest.com

China is cool.

 

[TheDieselZ]

KS-Tek.
They have some stuff on Amazon, else from their website, else from AliExpress. AliExpress cheapest, most variety. Amazon most expensive, least variety.

Don't want China?
Tisch

Tisch Scientific Filter Syringe .22μm PTFE 25mm - Sterile Individually

Tisch Scientific Filter Syringe 22μm Ptfe 25mm – Peptide Test Lab Supplies - Fast, accurate, and trusted.

peptidetest.com

Do you know of a good gun styled device or other that makes pressing on the the syringe to push oil through filter is easier?

 

[JuiceStick]

Caulk gun. Or battery powered caulk gun

 

[Kralteramon]

Caulk gun. Or battery powered caulk gun

You'll break the filter membrane. I use a 10ml syringe and a larger gauge needle. 19g or 21g. Takes about 1-2 minutes per vial.

 

[Sampei]

Do you know of a good gun styled device or other that makes pressing on the the syringe to push oil through filter is easier?

Change syringe size, best option

 

[JuiceStick]

50ml syringe works well with a washer in front of it