Steroid Profile Deca Durabolin

[xrayphoton13]

My initial thought is that it would make my wife angry and frustrated because my junk would not work properly, but I keep hearing that running Deca 1:1 does not affect everybody the same way. I need more testosterone with it.

That's true but high 1:1 seems to be the way to get the worst effects in a lot of people. Both his doses are under 200mg so he'll probably be fine. I think high test low deca or vice versa is the best approach for a mass cycle to avoid sides. I've tried 1200mg deca 100mg test without issue other than feeling lazy. I've also tried 1000mg test and 120mg deca without issue. But I haven't tried both mid to high yet to test the waters

 

[malfeasance]

That's true but high 1:1 seems to be the way to get the worst effects in a lot of people. Both his doses are under 200mg so he'll probably be fine. I think high test low deca or vice versa is the best approach for a mass cycle to avoid sides. I've tried 1200mg deca 100mg test without issue other than feeling lazy. I've also tried 1000mg test and 120mg deca without issue. But I haven't tried both mid to high yet to test the waters

I have tried it low 1:1 and same thing. No more for me.

 

[Theworm]

My initial thought is that it would make my wife angry and frustrated because my junk would not work properly, but I keep hearing that running Deca 1:1 does not affect everybody the same way. I need more testosterone with it.

Right I did 2:1 deca to test, no issues with libido

 

[brutalbuilt]

i always run higher test with deca and i get no sides

 

[joeblow543212]

i always run higher test with deca and i get no sides

Last test/deca cycle i ran at 2:1, no probs in boner dept however it took forever to cum. Which was fun the first few times I'd always wanted to go longer, but honestly hammering away for near 45mins with no end in site got damn old very fast.

 

[brutalbuilt]

Last test/deca cycle i ran at 2:1, no probs in boner dept however it took forever to cum. Which was fun the first few times I'd always wanted to go longer, but honestly hammering away for near 45mins with no end in site got damn old very fast.

that only happens to me on ecstasy

 

[Matthewwillams87$]

Deca Durabolin (nandrolone decanoate) or just "Deca" is probably the best known and most popular anabolic steroid after testosterone. What makes it so special? Why is it so widely revered? While most love it, why do some people disfavor it?

@Bill Roberts discusses in this popular steroid profile written for MESO-Rx. Please share your thoughts, opinions, and experiences regarding Deca.

Deca Durabolin (Nandrolone Decanoate)

Deca Durabolin is one of the oldest most popular anabolic steroids of all time. Well-suited for mass Deca Durabolin also provides strong joint relief for individuals

thinksteroids.com

I was wanting to start a cycle I'm 38 years old and need something to help me build more and faster then what I am now please help

 

[Ateam2023]

I was wanting to start a cycle I'm 38 years old and need something to help me build more and faster then what I am now please help

this is the MOST Ridiculous request, Much more information is needed, Please go to "New Member" thread and introduce yourself to the Meso Community and state your stats, current/previous cycles and peds used, No one can help you with no data, ,

 

[johnnytren]

Probably my favorite compound for bulking, amazing for my shoulder and knee pain too. Currently running 1g of test e a week, gonna throw in 600 deca

Last test/deca cycle i ran at 2:1, no probs in boner dept however it took forever to cum. Which was fun the first few times I'd always wanted to go longer, but honestly hammering away for near 45mins with no end in site got damn old very fast.

Damn thought I was the only one. No ED but sometimes me and the Mrs were going at it for an hour straight and I felt like I was getting no where lol

 

[Jesintn]

Saw a post of Justin Compton today saying he didn’t like deca bc it caused skin issues for him

Had some cystic acne issues before deca, and on deca. Have had seven cysts cut out of back of head, back, two neck , same spot, three on armpits. They seemed to clear up with doxycycline. Currently taking p5p and b6 , which supposed to be good for acne . Has anyone else had cystic acne before on deca, and if so how did you get rid of it , and or make sure it didn’t come back ?

 

[Ateam2023]

Saw a post of Justin Compton today saying he didn’t like deca bc it caused skin issues for him

Had some cystic acne issues before deca, and on deca. Have had seven cysts cut out of back of head, back, two neck , same spot, three on armpits. They seemed to clear up with doxycycline. Currently taking p5p and b6 , which supposed to be good for acne . Has anyone else had cystic acne before on deca, and if so how did you get rid of it , and or make sure it didn’t come back ?

Accutane

 

[Jesintn]

Raised dosing to 600 mgs e5 days. Still using mucuna pruiens , p5p , b6. As dose goes up am thinking adding a dopamine antagonist like bromociptine some days.

Has anyone used bromociptine with deca and a glp ( sema or tirz) bc though experience glp mixed with t3, mucuna prow a, caused almost a mental breakdown, was also at lowest calories of year and losing fat and weight fast, has anyone combined these three,and had no negative effects, despite in contest prep low calories for you?

 

[xrayphoton13]

Raised dosing to 600 mgs e5 days. Still using mucuna pruiens , p5p , b6. As dose goes up am thinking adding a dopamine antagonist like bromociptine some days.

Has anyone used bromociptine with deca and a glp ( sema or tirz) bc though experience glp mixed with t3, mucuna prow a, caused almost a mental breakdown, was also at lowest calories of year and losing fat and weight fast, has anyone combined these three,and had no negative effects, despite in contest prep low calories for you?

I won't be much help but I ran bromo a long time ago before glp1s thanks to Lyle McDonald's bromocriptine book. All I I can really tell you if you haven't used it before is please start with a super low dose like quarter the tab up. I felt fine after a few hours so I took another quarter and that ruined the rest of my day as I couldn't stand up. Every time I tried I got extreme orthostatic hypotension. Had to stay in bed the rest of the day. Was miserable.

Have you tried methylene blue? That has solved my deca issues. I've never tried Mucuna purines

 

[Jesintn]

I won't be much help but I ran bromo a long time ago before glp1s thanks to Lyle McDonald's bromocriptine book. All I I can really tell you if you haven't used it before is please start with a super low dose like quarter the tab up. I felt fine after a few hours so I took another quarter and that ruined the rest of my day as I couldn't stand up. Every time I tried I got extreme orthostatic hypotension. Had to stay in bed the rest of the day. Was miserable.

Have you tried methylene blue? That has solved my deca issues. I've never tried Mucuna purines

Yes bromo typically comes in 2.5 mgs . 1/4 tab or 60 mgs is a good starting point, That is what I used earlier today. Always start small with anything. You can never go back if negative effects appear.

Never tried methylene blue. I have a handful of drugs Ive learned and used quite abit and alot , over the years, and I use them from from time to time and really dont like to deviate due to drug interactions or try too many new things esp ones I dont fully understand and or havent looked into and or havent made sense to what it is im trying to accomplish

In the case its raising dopamine and lowering prolactin which deca does, the higher you go the more it could hapens. After doing 210 mgs deca solo in 2022 for three months without using any dopamine raiser or prolactin lowerers, I went through severe depression, and felt it took nine months afterwrds, on basic trt and testosterone cycles for brain chemsitry to feel more normal again

 

[xrayphoton13]

Yes bromo typically comes in 2.5 mgs . 1/4 tab or 60 mgs is a good starting point, That is what I used earlier today. Always start small with anything. You can never go back if negative effects appear.

Never tried methylene blue. I have a handful of drugs Ive learned and used quite abit and alot , over the years, and I use them from from time to time and really dont like to deviate due to drug interactions or try too many new things esp ones I dont fully understand and or havent looked into and or havent made sense to what it is im trying to accomplish

In the case its raising dopamine and lowering prolactin which deca does, the higher you go the more it could hapens. After doing 210 mgs deca solo in 2022 for three months without using any dopamine raiser or prolactin lowerers, I went through severe depression, and felt it took nine months afterwrds, on basic trt and testosterone cycles for brain chemsitry to feel more normal again

Man that's tough. Glad you're in a better place now. I never tried deca solo but 210mg sounds very low for a compound that aromatizes little to nothing. You may have had low e2 as well. Anytime I ran deca without testosterone I also used dbol to be sure (methyl)e2 wasn't in the gutter.

This is old and really just questions whether deca aromatizes. I wish it had examples but still a nice read if you haven't seen it before: Does Nandrolone Aromatize Into An Estrogen?

This is a quote from @Type-IIx 's article https://thinksteroids.com/articles/...#h-the-apparent-libido-decrease-by-nandrolone showing low e2 from 200mg nandrolone and increased dopamine breakdown as well:
Factors that are likely to influence nandrolone’s failure to enhance – and even to diminish – libido include [8]:

• Estrogens: Nandrolone tends to lead to sub-normal estrogen levels in men at therapeutic doses up to 200 mg weekly. After 6 weeks, serum estradiol (E2) was reduced to 11 ± 9 pg/mL at a 100 mg weekly nandrolone decanoate dose, and to 14 ± 4 pg/mL at a 200 mg weekly nandrolone decanoate dose in normal men [14]. The influence of estrogens and estradiol on libido is not established, in men nor women; but there are some indications that suggest an inverse U-shaped curve with respect to estradiol concentrations and libido (with concentrations that are too low & too high causing reductions to libido).
• 5α-reduction to DHN, a weakened androgen: Nandrolone, unlike testosterone that is amplified to the more potent DHT in CNS & sex tissues by 5α-reductase, is diminished in its androgenic potency in these target organs by yielding DHN (5α-dihydronandrolone). There is corollary evidence that 5α-reductase inhibitors (e.g., dutasteride, finasteride) that reduce amplification of T to DHT are associated with reduced libido in healthy men. [15].
• Negative feedback (inhibition) of gonadotropins: Nandrolone, lacking the C-19 methyl group of testosterone, has more broad homology for the nuclear receptor superfamily, including the progesterone receptor (PR) given the effects of this modification on its stereochemical properties and conformational shape. It therefore contributes to dysregulate gonadotropin secretion that is under hypothalamic GnRH regulation, which includes the interplay between the secretion of luteinizing hormone (LH) & follicle-stimulating hormone (FSH) from the hypothalamus [positive regulators] & sex hormone-binding globulin (SHBG) and inhibin from the Sertoli cells [negative regulators], and T from the Leydig cell [negative regulator], in a more pluripotent manner than testosterone. Nandrolone serves to dysregulate this regulatory system by acting to:
  • exert negative feedback at the pituitary (LH secretion) via its aromatization to estradiol
  • slow down the rate of hypothalamic gonadotropin-releasing hormone (GnRH) pulse frequency by androgenic and estrogenic action
  • dysregulate hypothalamic regulation of T and gonadotropins via KNDy dendron signalling/pulsatility as a progestin or progesterone analogue
  • increase prolactin expression at high doses (via its aromatic product, estradiol) – elevated serum prolactin has a tertiary role in reducing libido (primarily by acting at the hypothalamus). [16].
• Increased dopamine metabolism (i.e., net breakdown): To this author’s knowledge, this is a novel putative mechanism, never before proposed, for how nandrolone may contribute to reduced libido:Nandrolone increases serum homovanillic acid (HVA) in man [14], reflecting its metabolism (i.e., breakdown), and is likely related to reduced dopamine receptor number.Serum homovanillic acid (HVA) changed significantly in nandrolone decanoate at 100 mg weekly (+17.6 ± 7.7 pmol/L) and nandrolone decanoate at 300 mg weekly (+11.0 ± 3.3 pmol/L) but not in testosterone enanthate at 100 mg nor testosterone enanthate at 300 mg weekly groups [14]. Thus, even at clinical therapeutic dosages, there is a nandrolone effect on dopamine metabolism.Erotic stimuli of an audiovisual nature decreases HVA [17], reflecting increased dopamine activity associated with sexual arousal.It follows then, that if dopamine activity is integral to libido and manifestations of genital response and thoughts about sex arising from central arousal (reflected by decreased HVA), that nandrolone’s effects on dopamine metabolism (reflected by increased HVA) could effect a reduced sexual arousal.

 

[Jesintn]

All good stuff. Type-IIX knows his chemistry and hormones. I did 210 mgs deca solo as part and of a “cruise”

If I could go back or recommend, it would be either dhea or dbol, or both low doses. In addition to something like mucuna forty percent or higher that lowers prolactin and raises dopamine

I had massive negative effects to bromociptine at only 62 mgs as this was my first day using it
Headache , low blood pressure. That said it could be Im in competition prep and expected to feel this way with compromised sleep due to lack of calories.

 

[Jesintn]

Taking bromociptine before bed for some have reduced some of the negative effects. I took it before first meal. Also it can increase sexual urges I read , due to increased dopamine and this seems true from my experience of only one day

 

[The Answ3r]

In 10 years I have never touched Deca, just EQ, Mast and Tren. For my next cycle I am thinking it might be time to give it a try, but I am not sure whether to start with Deca or NPP. The plan is Test C 400 mg, EQ 500 or Mast E 300, and for the first run maybe NPP at 200 to 300 mg. I am leaning toward NPP because I have heard all the Deca horror stories, mood changes, “Deca dick,” you name it, and at least NPP clears out quicker while Deca hangs around for 3 to 4 weeks if I am not mistaken. What do you guys think? How and how much would you start with?

 

[Ateam2023]

In 10 years I have never touched Deca, just EQ, Mast and Tren. For my next cycle I am thinking it might be time to give it a try, but I am not sure whether to start with Deca or NPP. The plan is Test C 400 mg, EQ 500 or Mast E 300, and for the first run maybe NPP at 200 to 300 mg. I am leaning toward NPP because I have heard all the Deca horror stories, mood changes, “Deca dick,” you name it, and at least NPP clears out quicker while Deca hangs around for 3 to 4 weeks if I am not mistaken. What do you guys think? How and how much would you start with?

if nothing else the npp clears quick if you have to bail out, i ran mast with npp and it did help with npp blues, start low and titrate up as you tolerate it,,

 

[The Answ3r]

if nothing else the npp clears quick if you have to bail out, i ran mast with npp and it did help with npp blues, start low and titrate up as you tolerate it,,

Thanks, that’s what I was thinking. I’ll start at 200 mg and see how I feel from there. Funny how when I was younger it was just “send it” with any dose, and now it’s all about being smart, cautious, and starting low… ah, the wisdom of age.