I know, i was adding data (n=1 but dude said "no one posting labs")
MESO-Rx
Anabolic Steroids
How did the myth start that Primobolan was an AI?
- Thread starter eryximachus
- Start date
malomkarom
Member
Now masterone is one that has barely ever been shown to alter E2 at all. Dude you gotta read shit up, a quick chatgpt question for every hormone you use is not gonna end well.
The drug was sold for 40 years for this purpose. It has an FDA indication for this purpose. Large numbers of studies can found on pubmed.
The brand name Masteron comes from the greek word mastos, for breast, because it blocks estrogen receptors in the breast slowing the rate of breast tumor growth.
The level of stupidity here is shocking. Positively shocking.
Then what was it designed for?
I realize that a major demand driver of the internet is for people to feel superior to others, but this is a forum that is dedicated to education and harm reduction. If you just want to feel all superior, you can go to reddit and get a million upvotes talking about how you want to transition to a female or some shit.
If I am incorrect, then by all means explain to me why I am incorrect.
I do not discount that people here are either posting labs or reporting this phenomenon. But a few random people on the internet just isn't sufficient, for all the reasons I have stated. It may very well be that some people react to this drug in ways no researchers noticed for a half century for reasons no one knows or understands.
And it seems that is going to be the only resolution to my inquiry. But I find such an answer very odd and unscientific.
But thank you for contributing your labs.
malomkarom
Member
That statement is somewhat correct-ish. It doesn't effect E2 levels at all in an overwhelming majority of people. That's 90% percent.
You just keep giving chatGPT very general questions without having trained it first to find good sources. You are so dumb it hurt to read this thread.
This forum has way more than enough cycle logs with bloodwork on test+primo. Go read any single one of them with the bloodwork.
Not sure that even would be of any productive value, seeing you literally telling everyone they're lying when mentioning their own results.
Primo works as an AI in a large enough majority that you have to cling on to 1 single guy's opinnion to go againt the entire community. You barely get that effect, okay, good for you.
You are the singular one in a million.
BigTomJ
Member
It was used as an adjunct medication in support of estrogen sensitive breast cancer simply because it wasnt subject to aromatization.
Not because it directly interacted with estrogen or ER in any way.
Here you go, educate yourself rather than perpetuating lazy bro science.
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That is not what I have said.
The conclusion here is that the current, very new members of meso-rx are claiming:
1) That the scientists at Schering AG were idiots, who for 50 years did not realize a drug they manufactured was in fact the most powerful aromatase inhibitor known. And this was during a time where pharmaceutical companies were investing billions of 2025 dollars researching aromatase inhibitors.
2) That Bill Roberts is an idiot
3) That all the members on Meso-RX who were posting from 1999 to 2023 were idiots.
malomkarom
Member
Not a single one of us has said anything like that.
Noone. Not a single soul.
Again, what you are claiming in this very post is that that the scientists of Schering AG were complete fools who for a half century were unaware that a product they manufactured was the most powerful aromatase inhibitor known to man. This was at a time where a number of pharmaceutical companies invested billions of 2025 dollars trying to find this very kind of drug.
Interestingly, you are also claiming that the scientists at Eli Lilly and the FDA conspired to falsely bring to market drostolone for the treatment of breast cancer, because clearly has has no particular effect on estrogen in any way of relevance.
And then you are also claiming that everyone on Meso-RX from before 2023 - for a period of at least 23 years - were also fools.
So we have a vast conspiracy of scientists at two famous pharmaceutical companies manufactures, the Food and Drug Administration, and all the members of this website from the period of 1999 to 2023.
When you are claiming that such a vast conspiracy is underway, is that not madness?
malomkarom
Member
Are you aware that serum E2 doesn't mean breast tissue 1:1?
IndividualMan
Member
noone said this. a compound that maybe crushes your E2 when using 400mgs is less powerful than letrozole, which is almost guaranteed to completely crush your E2 on orally ingested 2.5mg per day (very high dose in our context, but not in a medical context, in which it is still far less than 400 mg of an injectable which is dosed at 100mg/ml and causes androgenic side effects)
he is unaware of/ignorant towards the existence of Selective Estrogen Receptor Modulators
Listen - I'm done with this.
You can believe what you want, but there is no science here. A few bros with labs is insufficient to entirely contradict the logical points I have made, never mind my personal experience (and labs).
If you'd like to believe that the scientists at Schering and Lilly and the FDA were idiots for a half century, be my guest.
Where did this clown was hiding in the last 10+ years? Is he having a manic attack like right now that keeps increasing in intensity and chromosome strength?
Did someone hack his account?
Did someone hack his account?
Drostanolone was dosed at 300-400mg weekly.
malomkarom
Member
Science is n=1 x a lot throughout history. If you're gonna ignore each and every individual, you are not going to see the big picture either. There's more than enough evidence. All you have to do is a google search.
Still noone has said or believed that, nor have any of the mentioned ever said Primo doesn't lower E2.
Not sure what you're holding onto at this point, cause nothing you say has any real base to it and the statements you are trying to argue have never been made.
I was living life. And I have a low tolerance for assholes, which you have been in this conversation since minutes after my first post.
Had civility prevailed early on, I probably would be less inclined to engage the persistent irrationality in this thread.
So I have you to thank for inspiring me.
malomkarom
Member
Honestly, this is fucking fun!
Never thought I'd find so many knobheads with less functional brains to mine.
Never thought I'd find so many knobheads with less functional brains to mine.
malomkarom
Member
What's your current weekly dose of Tren/Ment eryx? You know it might be your ratio of test
rimo and your estrogenic signaling being way off right?
rimo and your estrogenic signaling being way off right?
A handful of people posting bloodwork that contradicts my own is not sufficient.
There was one meso-rx post from 2023, which while interesting, still doesn't explain why no one on this forum was aware of the estrogen reducing properties of Primoblan until that time. I can find no mention of on this forum.
This is all basic logic that is ignored.
Why did no one notice these properties of Primobolan on this forum until 2023? What was going from 1999-2023 that prevented us from noticing this?
I have asked this question in various permutations multiple times here, no one can answer me.
So far as denying my logic regarding Schering - you are claiming like others that the scientists at Schering were idiots. That Primobolan could have been used to treat breast cancer from 1961 until the 1990s, but it was not used for this because they were stupid. They did not look at Masteron and ask themselves - hey, our drug is a DHT derivative too. Maybe our drug can be used for breast cancer?
That's what you are saying.
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