MESO-Rx
Anabolic Steroids
Did RU58841 stop hair loss against Tren for those prone to hair loss?
- Thread starter prher
- Start date
just some dude
Member
following
I think there is only one way to know, and that’s trying for yourself. I would have a hard time believe in that it doesn’t though if you use a high enough concentration of RU to saturate the AR. I’m still curious on some anecdotes though.
Broccolihead
New Member
Ru has worked extremely well for me on shit like tren, mast, proviron. Will say that I haven’t found the hair loss on tren to be nearly as bad as people make it out to be even without ru, feel like mast is way worse. All highly individual tho.
appreciate the input
out of curiosity when you run tren what does the cycle look like? test kept low? high?
Broccolihead
New Member
Yea I usually won’t have my test over 200mg, when my e2 gets even mildly elevated is when I start getting all the textbook tren sides otherwise I’m relatively fine.
ascending0roids
New Member
depends on how high the tren is and the concentration of ru/dmso also what other steroids ur using
I’ll say that I am not prone to hair loss. But I’ve been on primo non stop for 7 months, and was on primo and tren for 6 weeks with tren maxing out at 500 mg a week (tren a).
Used a minox/fin/ru topical mix the whole time. And looking at old pics I’ve actually filled in a space that was receding naturally. Was actually just looking at this today and was very impressed.
Used a minox/fin/ru topical mix the whole time. And looking at old pics I’ve actually filled in a space that was receding naturally. Was actually just looking at this today and was very impressed.
Here's a chart ChatGPT generated, you can see tren at the bottom
| Steroid | AR Binding Affinity | Ester / Half-life | RU58841 Effectiveness | Notes |
|---|---|---|---|---|
| Testosterone base | Moderate | Short |  High | Rapid dissociation → frequent AR “windows” for RU58841 |
| Testosterone propionate | Moderate | Short (~1 day) | High | Short ester → fairly easy for RU58841 to compete |
| Dihydrotestosterone (DHT) | High | Very short | ⚖ Moderate | Strong binder but short half-life → RU58841 works if applied consistently |
| Nandrolone (base or propionate) | Moderate | Short/medium | Moderate | Lower AR affinity than tren → RU58841 can compete |
| Boldenone (base or acetate) | Moderate | Short/medium | Moderate | Similar to nandrolone, fewer “locked” ARs |
| Testosterone acetate | Moderate | Short (~1 day) | High | Quick release → AR becomes available often |
| Testosterone enanthate | Moderate | Long (~7–10 days) | ⚠ Low | Long-acting ester → RU58841 cannot consistently block AR |
| Nandrolone decanoate | Moderate | Long (~7–10 days) | ⚠ Low | Long ester, slow hydrolysis → few AR windows |
| Trenbolone base | Very high | Short | ⚠ Low | Strong binder, slow dissociation → RU58841 struggles |
| Trenbolone acetate | Very high | Short (~2–3 days) |  Very low | Strong + slow dissociation + moderate ester → hard to block |
| Trenbolone enanthate | Very high | Long (~7–10 days) | Very low | Most difficult to block; AR effectively “locked” for days |
Did you mix this your self? I have a min/fin solution and was considering adding RU to it.
I bought a min/fin solution and an ru and mixed them together. But I didn’t source raws and make it if that’s what you’re asking.
I’d love to to find all these things raws and learn to mix it myself. It’s pretty expensive the current way I do it lmao.
Erased a chunk to try and not take up a whole page.
There are no significant human studies on tren. So there’s no studies on tren and hair loss. ChatGPT is at best looking through anecdotal evidence which is what this forum exists for.
Anecdotally I’ve read plenty of user experiences that ru maintained hair while on tren cycle. Was my experience as well. And these anecdotes are all we have to go on.
A ChatGPT chart does not bring value to the conversation. Op can just ask ChatGPT himself. And I thought chat was no longer going to use forums as sources? If that’s true then I have no idea where it would get data on a subject like this.
Turkeybuilder
Member
Where do you even get RU from
If you are stateside, minoxidil max is great. It's where I get my topical minoxidil and finasteride from. They also have it in liquid form.
Turkeybuilder
Member
Thanks brother
5TheNegative
New Member
Have not tried tren yet, just recently with deca so we will see.
But the Ru has worked well with primo, mast, var, and of course my trt.
But the Ru has worked well with primo, mast, var, and of course my trt.
ChatGPT is using the known pharmacokinetics of tren and ru58841 to deduce its effectiveness,
OP posted: "I would have a hard time believe in that it doesn’t though if you use a high enough concentration of RU to saturate the AR"
Tren has 10-15x more binding affinity to the AR than ru58841, Tren stays bound to the AR a magnitude longer than ru58841. ru58841 is cleared faster from the body than tren. Tren's chemical properties make it the single handed the worst steroid to try to block with a AR antagonist
Again tren has zero human studies. Our best knowledge on tren comes from decades of experience.
That’s why forums like this exist. If we wanted low bar ai answers we can head over to Reddit where a bunch of kids who spend all day watching Vigorous Steve and have no real experience can educate us.
Smartfart33
New Member
Do you guys derma roll before applying RU for better absorbtion?,
also is this formula good
"Weigh 3 grams RU58841 using a precision scale (0.001 g accuracy).Add 60 mL ethanol into a glass beaker or mixing container.Pour in the RU58841 powder and stir until fully dissolved.Add 40 mL propylene glycol and stir until uniform.Transfer to amber glass bottles (e.g., 2 × 50 mL or 4 × 25 mL bottles).Label bottles with concentration + date.Store in fridge (4–8°C) — stable for ~2 months."
also is this formula good
"Weigh 3 grams RU58841 using a precision scale (0.001 g accuracy).Add 60 mL ethanol into a glass beaker or mixing container.Pour in the RU58841 powder and stir until fully dissolved.Add 40 mL propylene glycol and stir until uniform.Transfer to amber glass bottles (e.g., 2 × 50 mL or 4 × 25 mL bottles).Label bottles with concentration + date.Store in fridge (4–8°C) — stable for ~2 months."
