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Don’t waste your money on oral peps
I’ve heard the issue with Slu pp is the low dosage of 1 mg for humans doesn’t correlate with the studies, and should be in the magnitudes of 50/100mgs?
Contrary to what the yt chiropractor says, there are several peptides with decent oral bioavailability/efficacy, SLU-PP-332 being one of them.
I think it’s still like 50% right? But the injectable form seems sketchy having to use DMSO as well when reconstituting
 
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Here you are . Numbers
 
I’ve heard the issue with Slu pp is the low dosage of 1 mg for humans doesn’t correlate with the studies, and should be in the magnitudes of 50/100mgs?

I think it’s still like 50% right? But the injectable form seems sketchy having to use DMSO as well when reconstituting
Oral bioavailability of SLU was ~45% according to what I read somewhere. There has been much discussion about human equivalent doses when compared to the studies, but my personal opinion is that it has notable benefits at doses far below what would be equivalent.

As Photon said, don't inject DMSO. Not sure where you read that, but that's terrible advice. A transdermal may be possible using crushed tabs and DMSO, perhaps that's what you saw recommended?
 
Oral bioavailability of SLU was ~45% according to what I read somewhere. There has been much discussion about human equivalent doses when compared to the studies, but my personal opinion is that it has notable benefits at doses far below what would be equivalent.

As Photon said, don't inject DMSO. Not sure where you read that, but that's terrible advice. A transdermal may be possible using crushed tabs and DMSO, perhaps that's what you saw recommended?
Got a source for that claim? It has never been used orally in any study.

Didn't do anything for me at 500mg a day (not mcg) and that batch from SSA was tested multiple times by different people. Didn't feel a thing or see any effects.

Did a quick search on it and all I could find was:
The same research group reports an orally active follow on compound, SLU PP 915, and the abstract snippet explicitly contrasts it with SLU PP 332, which “lacks oral bioavailability.”

The SLU-PP-915 authors are interpreting the literature and their own work to say SLU-PP-332 does not have sufficient oral bioavailability for practical use as an oral drug in vivo, which is why they moved chemistry to a new analog that does.


A university write up on the compound explicitly frames a key “next step” as refining it into a pill instead of an injection, which is consistent with “not orally workable as is.”


Bottom line: in the scientific literature, SLU-PP-332 hasn’t been shown to be orally bioavailable in a way that delivers meaningful blood levels or efficacy by mouth. SLU-PP-915 was developed because SLU-PP-332 lacked that property.


In other words, as I suspected, anyone that claims this drug does anything when they use it orally is full of shit. The research group that developed both compounds states that SLU-PP-332 lacks oral bioavailability. That paper was published THIS MONTH.
 
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I’ve heard the issue with Slu pp is the low dosage of 1 mg for humans doesn’t correlate with the studies, and should be in the magnitudes of 50/100mgs?

I think it’s still like 50% right? But the injectable form seems sketchy having to use DMSO as well when reconstituting
Just grab some oral SLU-PP-915 and you'll be good to go.
 
OK results are now publicly available

Vial kit A.
Bought from GB
Tested at 12.50mg, 94.734% purity, 0.854% dimer
Stored in freezer.
Bought in October


View attachment 370470
Vial kit B.
Bought from GB
Tested at 8.85mg, 75.174% purity, 0.409% dimer
Stored in fridge.
Bought in October. Received in November

View attachment 370484

View attachment 370476

View attachment 370477
View attachment 370478
Shit. October is when I bought. It arrived early November. Both of these are probably from the same batch since both were purchased in October.

Now wondering if I should take it. Don't want immunogenicity to hgh. I bought 8 kits. Argh! I have a planned blood test here in 3 weeks, maybe I will take and test thru blood. However, it could be sketchy vials scattered through out so even testing with blood won't mean a lot.
 
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Got a source for that claim? It has never been used orally in any study.

Didn't do anything for me at 500mg a day (not mcg) and that batch from SSA was tested multiple times by different people. Didn't feel a thing or see any effects.

Did a quick search on it and all I could find was:




Bottom line: in the scientific literature, SLU-PP-332 hasn’t been shown to be orally bioavailable in a way that delivers meaningful blood levels or efficacy by mouth. SLU-PP-915 was developed because SLU-PP-332 lacked that property.


In other words, as I suspected, anyone that claims this drug does anything when they use it orally is full of shit. The research group that developed both compounds states that SLU-PP-332 lacks oral bioavailability. That paper was published THIS MONTH.
The only reference for the 45% claim that I could find was Wikipedia, and that's obviously not at all reliable. It seems that the oral bioavailability numbers were possibly something fabricated by companies with a vested interest in selling oral versions of it.

The studies I saw referenced intraperitoneal injection as the form of administration. There was a mention in one of the studies of increasing the oral bioavailability by creating a pro-drug version, something like SLU-PP-332-Acetate. It would be a huge stretch to assume that the wording there, "increase oral bioavailability", could possibly imply some oral bioavailability vs them saying something like "in order to give the drug oral bioavailability", but maybe it has some very limited oral bioavailability? If that's true, it would mean the doses would need to be even higher than the adjusted mouse to human equivalent doses, since the mice received injections.

It is definitely curious how many people report effects on mcg doses. Placebo is a hugely powerful thing, so of course it is possible that every bit of the anecdotal positive benefits are nonsense.

I have 80 vials of 5mg injectable SLU-PP-332 that I'm waiting to use. I've heard conflicting information about its ability to suspend in aqueous solution, as well as how long it stays good once reconstituted. I was planning on doing one vial a day for a while to see if it did anything, but if the doses really need to be as high as the equivalency doses would be, I barely have enough for a few days. Hopefully SLU-PP-915 becomes available at reasonable prices.
 
Anyone bought and used the Slu pp 100 mg tablets? Any jano tests out for it? Or people down to do a group test
bought it, and using it at 400mg a day. I notice nothing from it really. Either SLUPP is just over hyped BS or this stuff is not 100mg tabs.
I have not tested it. I just wanted to test this stuff at a high dose on myself. I tried it in the past buying 500mcg tabs, and just used a ton of pills each day. up to 25mgs. I noticed nothing. So I wanted to give it a chance at a high dose before I say I will not spend money on this stuff again. If its doing anything, its nothing I can see without some tests. Only thing I may possibly be willing to test run is the injectable version, but im kind of over this product so no plan on trying that anytime soon
 
Shit. October is when I bought. It arrived early November. Both of these are probably from the same batch since both were purchased in October.

Now wondering if I should take it. Don't want immunogenicity to hgh. I bought 8 kits. Argh! I have a planned blood test here in 3 weeks, maybe I will take and test thru blood. However, it could be sketchy vials scattered through out so even testing with blood won't mean a lot.

I believe you can filter these to help.

@Ghoul would be better qualified to answer this
 
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