Wuhan Wansheng Biotechnology Co., Ltd. (USA, International)

The Dec 2025 paper on oral availability of slu-pp-915: https://www.sciencedirect.com/science/article/pii/S0022356525403000

Short story is oral administration works well for 915. Its starting to show up here and there.

The issue with all these new stuff is that the cost is prohibitive and not feasible in any way to use.

In order to test the effect of SLU-PP-915 on aerobic exercise performance, exercise-trained (1 hour daily running on a treadmill at 14 m/min) or untrained mice were treated with SLU-PP-915 using MDA for 7 days, twice a day (32 mg/kg).

32mg/kg in mice, means we need to take ~200-250mg.
It will not be feasible in any way for a very long time.
 
The issue with all these new stuff is that the cost is prohibitive and not feasible in any way to use.

In order to test the effect of SLU-PP-915 on aerobic exercise performance, exercise-trained (1 hour daily running on a treadmill at 14 m/min) or untrained mice were treated with SLU-PP-915 using MDA for 7 days, twice a day (32 mg/kg).

32mg/kg in mice, means we need to take ~200-250mg.
It will not be feasible in any way for a very long time.
I think i saw highest gene expression with 8mg with a benefit almost as good as 16 and 32mg.
Doesnt change your point though. Finished 915 is about $330/g and synthesis of it is more complicated than 332 so doubt we will see $3.60/g prices on it any time soon. So $65-85 a dose for 32mg HED, $15-20 for 8mg HED.
 
You should always filter you HGH and peptides. How often is anyone testing for endotoxins, contaminants, etc.... I never see this. But yet purity c9mes back at 95, 96, 97%.... what else is in your vial?

And yes filtering your HGH will help remove impurities as well as degraded HGH proteins and help reduce developing immunogenicity.

.22um PES sterilized filters.
Hello thank you for this, is there a post that has a step by step process on how to do this? Thank you
 
Filter it and immunogenicity risk will be minimized.

From a presentation by the FDA a while back. These are all GLP peptides tested for immunogenicity response.

The commercial ones on the left all had low level reactions, as they’re carefully engineered to.

The two on the right are from compounding pharmacies, “legal UGL” using Chinese raws. Look at how much higher immunogenicity is.

View attachment 370639

This is immunogenicity before and after filtering. 80% drop in one of the compounded GLPs (the other was probably reduced significantly but still off the charts).

View attachment 370640

By the way, the green bar is PURE ENDOTOXIN. The immune system response to compounded peptides was stronger to than to toxic bacterial cell walls, lol.
Thanks @Ghoul and others. I am into the hgh for about $1k so I will filter and run some blood work. Hopefully, it's not a pure waste. I wish the UGL could be more trustworthy but I guess until we as a community require regular refrequent vendor testing and hold vendors accountable, nothing will change.

There is a real opportunity for a vendor that is willing to test and guarantee product. Maybe one day someone will fill that need.
 
Thanks @Ghoul and others. I am into the hgh for about $1k so I will filter and run some blood work. Hopefully, it's not a pure waste. I wish the UGL could be more trustworthy but I guess until we as a community require regular refrequent vendor testing and hold vendors accountable, nothing will change.

There is a real opportunity for a vendor that is willing to test and guarantee product. Maybe one day someone will fill that need.
SSA was there. And then they got raided.
 
Thanks @Ghoul and others. I am into the hgh for about $1k so I will filter and run some blood work. Hopefully, it's not a pure waste. I wish the UGL could be more trustworthy but I guess until we as a community require regular refrequent vendor testing and hold vendors accountable, nothing will change.

There is a real opportunity for a vendor that is willing to test and guarantee product. Maybe one day someone will fill that need.
There's 2 vendors on here that basically always have 97/98% + with almost no dimer and sometimes no dimer. Even those vendors you should be filtering. SSA and Q were decent to me, my SSA all tested 97+ with almost no dimer for my H36 kits. Q atleast is doing testing on EVERY batch they sell, not the best but atleast you know what you got haha.

Think of it this way, every test you see from Jano has been filtered prior to testing. If you want to be injecting the same as what Jano test shows you need to filter it before. Who knows what other bullshit could be in there prior to filtering.

I bought some H36 kits on my last order from WWB and I will 100% be sending that in with the current state of things. Luckily they're not even for me as I am finishing my SSA kits and then moving to the 2 members I mentioned.
 
There's 2 vendors on here that basically always have 97/98% + with almost no dimer and sometimes no dimer. Even those vendors you should be filtering. SSA and Q were decent to me, my SSA all tested 97+ with almost no dimer for my H36 kits. Q atleast is doing testing on EVERY batch they sell, not the best but atleast you know what you got haha.

Think of it this way, every test you see from Jano has been filtered prior to testing. If you want to be injecting the same as what Jano test shows you need to filter it before. Who knows what other bullshit could be in there prior to filtering.

I bought some H36 kits on my last order from WWB and I will 100% be sending that in with the current state of things. Luckily they're not even for me as I am finishing my SSA kits and then moving to the 2 members I mentioned.
I know this isn't the wisest choice but damn filtering peptides sounds expensive and time consuming. For something like GH where you go through a vial pretty quick. That's a lot of supplies.

Do you guys filter back into the same vials?

I know I know how much is your health worth.
 
I rest my case.
Seems like the science says SLU is useless orally, however BPC-157 and KPV seem to be less controversial when it comes to oral administration, no?
I'll personally pick an injectable over an oral 10 times out of 10, but I was talking oral and injectable BPC as I had read that the oral version offered more gastrointestinal benefits, while offering less regenerative/healing benefits.
 
I know this isn't the wisest choice but damn filtering peptides sounds expensive and time consuming. For something like GH where you go through a vial pretty quick. That's a lot of supplies.

Do you guys filter back into the same vials?

I know I know how much is your health worth.
Honestly the cobetter filters aren't to expensive. I typically load 2-3 40iu vials at a time into a Savio pen. 1ml each so 3ml/120iu total. I use a 3ml syringe to recon them, use the same syringe to draw all once they recon'd for like 8-12 hours(AM-PM) and then I filter directly into my 3ml cartridge for my pen.

I do the same for all peps. PES filter and into 3ml cart for my Savios. I also have 3ml sterile vials I use when all 3 of my Savios are being used haha. Always filter into new vial.

I also filter all oils even domestic into sterile 10/20ml vials using PTFE.

You're health is a small price of those filters and a few extra syringes a month.
 
Honestly the cobetter filters aren't to expensive. I typically load 2-3 40iu vials at a time into a Savio pen. 1ml each so 3ml/120iu total. I use a 3ml syringe to recon them, use the same syringe to draw all once they recon'd for like 8-12 hours(AM-PM) and then I filter directly into my 3ml cartridge for my pen.

I do the same for all peps. PES filter and into 3ml cart for my Savios. I also have 3ml sterile vials I use when all 3 of my Savios are being used haha. Always filter into new vial.

I also filter all oils even domestic into sterile 10/20ml vials using PTFE.

You're health is a small price of those filters and a few extra syringes a month.
At this point I'm filtering CN oils. Haven't gone beyond that. In between jobs so don't have the budget for all of the necessary supplies.
 
Honestly the cobetter filters aren't to expensive. I typically load 2-3 40iu vials at a time into a Savio pen. 1ml each so 3ml/120iu total. I use a 3ml syringe to recon them, use the same syringe to draw all once they recon'd for like 8-12 hours(AM-PM) and then I filter directly into my 3ml cartridge for my pen.

I do the same for all peps. PES filter and into 3ml cart for my Savios. I also have 3ml sterile vials I use when all 3 of my Savios are being used haha. Always filter into new vial.

I also filter all oils even domestic into sterile 10/20ml vials using PTFE.

You're health is a small price of those filters and a few extra syringes a month.
No issue with aggregation or cloudiness at 40iu/1ml? I looked at pens, but decided against it since I normally reconstitute at 10iu/1ml. Pen would definitely be great if I could load 3 vials of Hgh into it.
 
I feel like I'm back in early 2000's seeing people post as SWIM online. Law enforcement reading this "It's not him guys, it's someone who goes by the name Swim."

Legend has it, they are still after SWIM who has yet to be found. Hopefully you get your missing stuff though. Been hearing a lot missing vials for some reason. Maybe someone is scalping a vial or two for themselves off the top?

Ghoul is scaring me into filtering HGH too. Good info and reasons to filter. How rapidly could one develop immunogenicity to HGH and would you know if your serum GH levels keep testing low despite using high IU daily?
Hello thank you for this, is there a post that has a step by step process on how to do this? Thank you
 
Hello thank you for this, is there a post that has a step by step process on how to do this? Thank you

Also believe there are.video links throughout. Please use the search function. You will be able to find most topics and subjects there.
 
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