ED Issues Continue

Can you list your SHBG labs since you started TRT until now?

IIRC, it's gone up a lot.

70 mg twice a week? Ok, but do it as 40 mg eod. You and I both know that works better!
 
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Can you list your SHBG labs since you started TRT until now?

IIRC, it's gone up a lot.

70 mg twice a week? Ok, but do it as 40 mg eod. You and I both know that works better!
This is from an older post in this thread:

Oct. 2012 (ED) - This was when I was fucking around with a low dosage (20mg eod) with an hcg shot thrown in here and there instead.
TT - 579 (292-1052)
FT - 12.2 (4.8- 25)
SHBG - 34
E2 - 36 (<=63)

Oct. 2011 (no ED) - notes read I was doing EOD dosing at 98-112 mg per week based on...nothing really
TT - 979 (300-1080)
FT - 231 (47-244)
SHBG - 26 (11-80)
E2 - 40 (12-41)

Oct. 2010 (no ED) - notes read I was on 100-112mg t cyp weekly...I didn't note dosing protocol, but I recall it being twice weekly
TT - 909 (300-1080)
FT - 193 (47-244)
SHBG - 32 (11-80)
E2 - 62 (12-41)
 
I seem to remember your SHBG in the 40s at one point. Is that right?

The October 2012 reading has your fT kinda low. The low end of the 'normal range' for fT on that scale is useless. It's a good idea to increase your T dose. Aim for a tT in the 700s to get a fT somewhere between 16 and 22.
 
Warning: long post - TL;DR at bottom.

Well - I'm getting closer to figuring this out. And I think I have a theory. Thinking back to when I first started TRT, even at EOD injections, my erection quality (EQ) had taken a hit when not watching porn or having sex. In other words, rubbing one out in the shower was a semi-soft experience that it had never been before. Since everything else worked great, I didn't really care.

My libido also tapered down, but since I could rub one out and have sex when I wanted, I didn't care. Hell - I didn't really notice. Now that I look back on it, my libido was quite low (I also had other problems to deal with so I wasn't that concerned with it.) I remember a few times during this period where I had taken some arimidex I had laying around (really just playing around to be honest) and had rock hard morning wood and a strong libido to boot. I just kinda had fun with it, but didn't really think about it too much.

After about two years of the sub-par EQ and libido, both completely tanked - which is why I tried to restart, failed, and have been tinkering ever since. Now, I had lots of lab tests over this time, and E2 was usually in the 40s. Not great, but not horrible either. I'm wondering if for some reason, my body was OK with this initially, but finally just became over-saturated with the stuff. I'm also wondering if perhaps if I tested other types of estrogens that they would be much higher, and could be causing my issues?

I think this because I have finally been able to find some success and find the sweet spot, where libido is higher than I can remember in a LONG time (like, I gotta go to the bathroom and rub one out RIGHT now) with good EQ.

Going back through my recent experiences, my libido and EQ has been great when I am 4-8 days since my last injection. This seems to be the sweet spot.

Libido and EQ sucks when TT is 220, or even around 700-800 it seems, but great when it's around 500. How do I know?

When I was trying my restart my libido and EQ was good when I was doing around 1,000 iu hCG EOD. I was around 400 TT at this point.

Was OK on clomid (who knows what was going on here with TT and E2 though) and off clomid when my TT was around 550-470...this was actually the best I'd been since this all started. However, it didn't last as the dead dick re-emerged when I crashed and my TT fell to the 220s.


After that I went back on T Cyp. at around 24 mg EOD. Libido and erections were hit or miss at a TT around 700. PDE-5is worked though. I could summon up a libido occasionally but the EQ issue wasn't helping my drive.

hCG mono at 2,500 iu EOD caused a few initial spikes in libido and EQ but nothing spectacular. PDE-5is inconsistent but with a high enough dose they would work. E was higher at this point too (40s to 60s).

Then I was playing around with thyroid stuff. I noticed a boost in EQ and libido with them, but if you recall, I also took about a week where I just STOPPED DOING ANYTHING until my libido and EQ came back. It did about 5 days later. I was great (extremely high libido) for about 3-5 days. Then kinda back to back down a bit. I'm not sure why I injected again, I think I just felt like I should to be honest.

At 70mg T 2x per week (what doctor has me trying now) I noticed that initially I am not having a lot of success with it. PDE5is not working well. Well, on the day I am supposed to do my injection (yesterday) I notice that my libido is the best it's been on this protocol and my EQ is good. Held off on injecting and took a cialis today to check response - great response. I took some over the weekend (Friday, 4 days ago) and had a poor response, even at 10mg...I was able to have sex Fri and Sat but took way more effort than it should on my part...easier Sat than Fri.

It's obvious there is some sort of sweet spot, whether it's E2, TT, or SHBG related, that I am falling through (I'm guessing E2) I then am injecting, and going up through it, and staying above it until I give things a break. Then I fall into it, stay there for a few days, then lose it.

So...I'm wondering how to find this sweet spot and STAY in it?

This thread that both myself and LW commented in last year has me wondering if this is something good to try:
https://thinksteroids.com/community/threads/134307608

Wait until I hit the spot, and then try that real low dose EOD protocol and go from there?

Anyway, I'm going to keep giving what my doctor told me to try a shot, just to say I gave it a fair shake...which is 70mg 2x per week with 1mg per week of arimidex thrown in. In realizing the folly of my ways (not sticking with things long enough) I figure I ought to give this one some time to see if things fall into place.

I also wonder if a compounded gel isn't worth a shot either. Everytime I've tried a gel they end up giving me anxiety (I've always thought DHT but who knows) ...but it's been awhile.

tl;dr - finally had some success finding sweet spot, think that the folks who said E2 all along were right, and that before trying arimidex I just shot down and then rebounded up through it, because I didn't give it enough time. Need to figure out way to stay in sweet spot, which is either through regular arimidex, some sort of novel injection schedule, or maybe trying a compounded cream.
 
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Low-dose, eod injections, where you sometimes delay the next injection by waiting an additional 12 hours.
 
Hey dude

I have the exact same thing happen to me with regards to libido.

My libido is best 4/5/6 days post injection. And then it dips before the nxt inject.

Also, my libido is best around 500 (that's what i was consistently on the transdermals)

You have answered your question but you dont seem to see the answer yourself.

The ed or eod injections dont make sense to me. Test E has a fairly long half life. Its anywhere between 5-8 days. You say your libido is best from day 4-8. Why not inject weekly again? This should solve alot of your issues.

You will have a good libido most of the time and you will have a consistent dosing interval.

I think injecting too frequently can really fuck things up.

In my experience 6-7 days is the best injection protocol.

The reason being, the body is able to reach a better homeostatis (balance of everything including e2) when you have a consistent weekly dosing protocol.

I really believe guys are overkilling it with the doses and frequencies which is where some of the problems arise.


Going back through my recent experiences, my libido and EQ has been great when I am 4-8 days since my last injection. This seems to be the sweet spot.

Libido and EQ sucks when TT is 220, or even around 700-800 it seems, but great when it's around 500. How do I know?

I also took about a week where I just STOPPED DOING ANYTHING until my libido and EQ came back. It did about 5 days later. I was great (extremely high libido) for about 3-5 days. Then kinda back to back down a bit. I'm not sure why I injected again, I think I just felt like I should to be honest.

It's obvious there is some sort of sweet spot, whether it's E2, TT, or SHBG related, that I am falling through (I'm guessing E2) I then am injecting, and going up through it, and staying above it until I give things a break. Then I fall into it, stay there for a few days, then lose it.

I also wonder if a compounded gel isn't worth a shot either. Everytime I've tried a gel they end up giving me anxiety (I've always thought DHT but who knows) ...but it's been awhile.
 
What's happening to me is similar to what's happening to you...

Inject - go up through the sweet spot

4 days later - i am in the sweet spot. i feel good for 2-3 days.

6 days later - i am falling through the sweet spot. need to inject again.

It's fucking frusterating for sure.

It's obvious there is some sort of sweet spot, whether it's E2, TT, or SHBG related, that I am falling through (I'm guessing E2) I then am injecting, and going up through it, and staying above it until I give things a break. Then I fall into it, stay there for a few days, then lose it.
 
Low-dose, eod injections, where you sometimes delay the next injection by waiting an additional 12 hours.

He says his libido is best 4-8 days after injecting.

Clearly this doesnt indicate eod injections if he wants a good libido.

e5d MAYBE. but once/wk should best.

Cubbie, have you ever tried a lower dose inject? like 50mg/wk?
 
He says his libido is best 4-8 days after injecting.

Clearly this doesnt indicate eod injections if he wants a good libido.

e5d MAYBE. but once/wk should best.

Cubbie, have you ever tried a lower dose inject? like 50mg/wk?

I really do not agree with your logic, especially the bolded text.

It doesn't seem that it is the "time" since injecting that matters...but rather it is the T and E2 levels that are reached at that time that are relevant. They key is to find the levels that result in the best libido/mood/whatever and develop a protocol to maintain those levels.

I vote for cubbie running out the door and getting labs drawn when he is feeling a 5 star libido.
 
I could run out and get labs, but I think I have an idea of where they need to be anyway. I would like to reach that stable point and stay there before I run out and get them.

I don't want to fuck with the testopel because unless they get it right the first time I'll have to deal with it for 4 months.

LW, I think you are right...just need to find the correct dosage.
 
I could run out and get labs, but I think I have an idea of where they need to be anyway. I would like to reach that stable point and stay there before I run out and get them.

I don't want to fuck with the testopel because unless they get it right the first time I'll have to deal with it for 4 months.

LW, I think you are right...just need to find the correct dosage.

Start at a dose you're very certain is just a bit lower than what you need. Approach it from the bottom, not the top. The long half-life of T-cyp is what picks up the slack. When you inject eod, it stays close to the right level once you get to where you want to be and if it overshoots, it isnt by very much so its easier to recover.
 
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It doesn't seem that it is the "time" since injecting that matters...but rather it is the T and E2 levels that are reached at that time that are relevant. They key is to find the levels that result in the best libido/mood/whatever and develop a protocol to maintain those levels.

I vote for cubbie running out the door and getting labs drawn when he is feeling a 5 star libido.

I would bet my left nut sack those labs will come back in the 500's.

The thing is, I agree it's the perfect balance that's important. But it's very difficult to trouble shoot eod if you are over shooting the mark.

The reason being, even if you over shoot it, due to the half life of Test cyp or e it will take 5-7 days to come down and meanwhile you continue to shoot eod and you are overshooting it even more and more.

Your libido came back with a break in eod injects.

This shows two things:
1. Your eod dose is too high
2. You will continue to overshoot the mark eod bc of the half life issue


I agree you need to find the right dose but gluck finding it with eod injects
 
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I could run out and get labs, but I think I have an idea of where they need to be anyway. I would like to reach that stable point and stay there before I run out and get them.

I don't want to fuck with the testopel because unless they get it right the first time I'll have to deal with it for 4 months.

LW, I think you are right...just need to find the correct dosage.


This is basic math.

If you inject eod and you overshoot the mark it will take at least one half life to come down. If you overshoot and continue to inject eod you are tacking on more and more so it will take longer (possibly never) to come down.

The only way you will reach the sweet spot is if you take a break from eod like you did.

The point is, if you are injecting more frequently than the half life good luck trying to find the right dose... because every dose continues to get stacked on.... so if you are overshooting the mark you will never have a libido.
 
For the sake of completeness I may have to attach a spreadsheet that I made the first week I started TRT. It is a plot of mg T ester in blood versus time.

What you will observe is that there is no "stacking" effect.

When dosing frequently you reach a steady state. If there were "stacking," your levels would continue to climb the entire time you are on TRT.

By reducing your EOD dose, you will reach a new steady state level 5-6 weeks later.
 
Really?

I would think they would continue to climb.....

At least for awhile (until the back end injects fade out) but then i guess it would even out eventually.

For the sake of completeness I may have to attach a spreadsheet that I made the first week I started TRT. It is a plot of mg T ester in blood versus time.

What you will observe is that there is no "stacking" effect.

When dosing frequently you reach a steady state. If there were "stacking," your levels would continue to climb the entire time you are on TRT.

By reducing your EOD dose, you will reach a new steady state level 5-6 weeks later.
 
Really?

I would think they would continue to climb.....

At least for awhile (until the back end injects fade out) but then i guess it would even out eventually.

This would be true if you didn't reduce the dose and you injected EOD. By reducing the dose and injecting more frequently the peaks and troughs level out considerably. The more you do this the closer you get to steady state.
 
This would be true if you didn't reduce the dose and you injected EOD. By reducing the dose and injecting more frequently the peaks and troughs level out considerably. The more you do this the closer you get to steady state.

He's only been told this about, like, 475,986,647 times.
 
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