125mg t

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No legit doc concerned for your health is going to put you on TRT. You should ask yourself if you are chasing the feeling of being on 500mg? Once we ALL get past out early to mid twenties we miss being in our prime. That crazy ability to recover is something we all miss.

Now I understand that you are still a young man but you cannot compare a Natural 29 year old with a 25 year old on 500mg.

I strongly suggest you stay away from TRT with a level of 732. I would also stop arimidex if you do not have a documented need.
 
Honestly man, you might need hrt but only because your boosting your natural levels with arimidex, You should stop the arimidex and test your levels. Your probably feeling low because your killing too much estrogen, even men need some. And you might have felt low before because you do have low test and the only reason it got up to 700 was because the arimidex. I really dont believe the whole androgen receptor bullshit tho
 
Honestly man, you might need hrt but only because your boosting your natural levels with arimidex, You should stop the arimidex and test your levels. Your probably feeling low because your killing too much estrogen, even men need some. And you might have felt low before because you do have low test and the only reason it got up to 700 was because the arimidex. I really dont believe the whole androgen receptor bullshit tho

Nothing lowers it man, nothing does. It's persistently elvated and so is my LH.

And that bitch. That bitch who fucked me off because I couldn't get an hard on. She can kiss my ass. That bitch ain't worth it. She can fuck off.
 
Nothing lowers it man, nothing does. It's persistently elvated and so is my LH.

And that bitch. That bitch who fucked me off because I couldn't get an hard on. She can kiss my ass. That bitch ain't worth it. She can fuck off.

The question is again did you test positive for the gene?
What medical evidence does he have to make his diagnosis upon?
 
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The question is again did you test positive for the gene?
What medical evidence does he have to make his diagnosis upon?

He just looked at my bloodwork and my high T and LH levels. My LH as been as high as 25.3 and T levels almost in the 900 range.

He specialises in AIS just like Dr Crisler specialises in Low T. He's been dealing with these cases al his career.

I think the combined finding of raised testosterone and LH concentrations taken together with his high normal SHBG and HDL cholesterol are all indicative of a ,mild form of the androgen insensitivity syndrome.

I will probably get the test after I have a semen analysis. I know for a fact I'm infertile though because hardly anything comes out.

Depending on his future plans it might be worth considering a referral to clinical genetics for sequencing of the androgen receptor. Although the pickup rate in mild androgen insensitivity syndrome is quite low, it will be important to be thorough about the risk of transmitting androgen.
 
He just looked at my bloodwork and my high T and LH levels. My LH as been as high as 25.3 and T levels almost in the 900 range.

He specialises in AIS just like Dr Crisler specialises in Low T. He's been dealing with these cases al his career.



I will probably get the test after I have a semen analysis. I know for a fact I'm infertile though because hardly anything comes out.

why not just take HCG to suppress LH which it does do and bring T levels back down to normal or even possible lupron? This would be the most logical scenerio
 
why not just take HCG to suppress LH which it does do and bring T levels back down to normal or even possible lupron? This would be the most logical scenerio

I've read that hcg increases LH production. It's not really prescribed that much by docs over here. This is the UK. My first endo thought I was nuts for taking Nolvadex and Clomid. He said that he's never heard of a man taking those drugs. This just proves how little some of these docs in this country know.
 
I've read that hcg increases LH production. It's not really prescribed that much by docs over here. This is the UK. My first endo thought I was nuts for taking Nolvadex and Clomid. He said that he's never heard of a man taking those drugs. This just proves how little some of these docs in this country know.

It lowers it on serum as I have seen this time and time again with Dr's whom I have consulted with their patients just running HCG monotherapy. I think your Dr needs to go back to the drawing board with his methodology. As noted most Dr's in uk are in the dark ages.

hCG suppression of LH receptors and responsiveness... [Mol Cell Endocrinol. 1977] - PubMed result

You where nuts for taking clomid because that increases LH LOL
When running clomid challenge this is easily observed and one of the clinical responses looked for along with higher T levels.

Your dr is barking up the wrong tree if the desired out come is lower LH
 
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Wowzers, I would certainly be hesitant to start a 29 year old male with a higher end test on replacement therapy. Eventually that 125 will shut you down and may end up giving you a lower level than you started with unless your dose is titrated. You may want to avoid this path.
 
Wowzers, I would certainly be hesitant to start a 29 year old male with a higher end test on replacement therapy. Eventually that 125 will shut you down and may end up giving you a lower level than you started with unless your dose is titrated. You may want to avoid this path.

What is the intent of the outcome of treatment? What is he trying to accomplish medically?
 
Wowzers, I would certainly be hesitant to start a 29 year old male with a higher end test on replacement therapy. Eventually that 125 will shut you down and may end up giving you a lower level than you started with unless your dose is titrated. You may want to avoid this path.

How many times do I have to say this for fucks sake? Have your read my other threads? I'm not normal like you and other men. I'm abnormal. I have "Mild Androgen Insensitivity Syndrome" and need higher T levels than normal men. This is pissing me off now.

Guys like you just look at my T levels and think, "whoa, you're normal, you don't need TRT". Just like my old docs.
 
How many times do I have to say this for fucks sake? Have your read my other threads? I'm not normal like you and other men. I'm abnormal. I have "Mild Androgen Insensitivity Syndrome" and need higher T levels than normal men. This is pissing me off now.

It's your own fault for starting multiple threads when you have such a rare condition. Not everyone here reads every thread. I know I don't (but I am familiar with your threads because rare cases are almost invariably interesting ;)).
 
I must have missed the part in this thread that mentioned you had MAIS. Unfortunately all I read was "bros my test is high, should I worry about shutting it down by supplementing it"?. I will try and research your history further so that I may be fully aware of your past medical history prior to commenting.
 
I must have missed the part in this thread that mentioned you had MAIS. Unfortunately all I read was "bros my test is high, should I worry about shutting it down by supplementing it"?. I will try and research your history further so that I may be fully aware of your past medical history prior to commenting.

Still have not heard if genetic test has confirmed it.
 
How many times do I have to say this for fucks sake? Have your read my other threads? I'm not normal like you and other men. I'm abnormal. I have "Mild Androgen Insensitivity Syndrome" and need higher T levels than normal men. This is pissing me off now.

Guys like you just look at my T levels and think, "whoa, you're normal, you don't need TRT". Just like my old docs.

What level do you think you'll need to feel better? 1200, 1700?

You were taking arimidex and nolvadex-- both boost T levels and T/E2 ratio (or at least nolva emulates it). Have you felt any better on them?
 
What level do you think you'll need to feel better? 1200, 1700?

You were taking arimidex and nolvadex-- both boost T levels and T/E2 ratio (or at least nolva emulates it). Have you felt any better on them?

Arimidex raised my libido slightly, I never checked what my T level got too but it must have raised it slightly because my LH dropped down to 9.3. Nolvadex made me feel better for 2 days after coming off it. I'm thinking that it raised my T to a decent level and LH dropped down to a normal level after coming off of it but it didn't last.
 
Arimidex raised my libido slightly, I never checked what my T level got too but it must have raised it slightly because my LH dropped down to 9.3. Nolvadex made me feel better for 2 days after coming off it. I'm thinking that it raised my T to a decent level and LH dropped down to a normal level after coming off of it but it didn't last.

Have you ultrasound of your nuts?
Because this is what common occurs with beginning stages of testicular cancer..
LH keeps pushing hard till eventually it stops responding because nuts are fried. This can happen at any time and can last for several months.

Has a Testicular leydig cell tumor been ruled out may be explaining the higher LH?
 
Have you ultrasound of your nuts?
Because this is what common occurs with beginning stages of testicular cancer..
LH keeps pushing hard till eventually it stops responding because nuts are fried. This can happen at any time and can last for several months.

Has a Testicular leydig cell tumor been ruled out may be explaining the higher LH?

It's not that. I've done 6 cycles. My first one was at age 21. I'm 30 now and none of them shut me down. The last cycle which messed me up completely was Testosterone at 500mgs for 9 months solid and it didn't shut me down. My T levels are still very high. Free T, Bioavailable T, DHT and Free Androgen Index is way over the range. This isn't normal. And My LH is always elevated. The only condition that can explain this is MAIS; and an international AIS specialist diagnosed me with it. He wouldn't have diagnosed me if he didn't think I had it.
 
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