DNP (crystal) with bioperine to increase potency

[Colin]

As a preface,I've used DNP (wet powder) before and found it top be very potent by itself and ridiculously cheap as well as I bought it from a bulk chem supplier.My former source no longer has it in stock (and has been out of stock for around 2 years so don't bother sending me a PM) and I've had to buy some crystal caps (250mg DNP each) which after a month's worth of usage I can safely say are much less potent than wet DNP.600mg wet DNP is the upper limit for me,I've gone as high as 750mg but the heat was unbearable.

With crsytal caps I've done a gram for a couple days straight with the remainder of the 10 day run between 500mg and 750mg per day.It looks like a gram is the sweet spot for crystal caps but this gets costly.At a gram,I'd compare the body heat to (at the most) 600mg wet DNP..

I read over on BB.com,of all places,that grapefruit increases the efficacy of DNP via CYP450 inhibition.Bioperine is also a CYP450 inhibitor and is quite cheap at around $5 per bottle of 10mg tabs.

So I'd like to know just how much bioperine (5 or 10mg) would one want to take in combination with 500mg crsytal DNP,with the intent of bring up the potency of 500mg crystal to the level of 500-600mg wet DNP.

Des also stated that there are a host of other enzymes that could be manipulated,CYP450 being just one of them,I'd like to hear some thoughts on these other avenues.

 

[Colin]

I'm updating this for those interested in the synergy between DNP (crystal) and bioperine.

I started dosing bioperine at 5mg with 500mg DNP 4 days ago and felt sluightly more heat for thew remainder of the day.The next day I upped the doser to 10mg bioperine with mt daily 500mg DNP,all taken in the morning in one lump sum as usual.

Effectsd from this protocol are about in line with 500-600mg of "wet" DNP.ideally I would be using wet DNP powder b/c it is cheap as balls at 100 grams for around $110 (google search shows the source right away FTR,which is legal) but they no longer have it in stock.

So I've had to resort to the secondary market and got stuck with the less potent crsytal version.So this is just an illustration/public service for those in a similiar situation who want to get the mosdt out of their dollar with crystal DNP caps.

Next run I will start at 750mg crystal and 10mg bioperine for 10 days abnd back down to 500mg/10mg for the remaining 4 days.

I strongly reccomend a Phenogen clone (Cozmar's bulk GPA # g ED for a week then 1.5 G for 5 weeks,NP's salvia powder 500mgx3 ED with food and GTE caps on an empty stomach).

More AMPK agonism via GPA which is money as it's basically an exercise mimetic and that with DNP is pretty damn profound.

I'm working on the formulation of Phenogen Ultra,licennsed from Avant to Live Long Nutrition and we'll be offering a (seperate) Super Sesathin as well.All will be in bulk form to keep costs down.

 

[Colin]

Bump for discussion.