Accutane permanent cure?

[adrenalytic]

Standard dosing in US is 1mg / kg and 2mg / kg is common, so 80mg / day being “far beyond” is absurd.

I may have left out a little context. I think what it was referring to was the speed at which I titrated up to 80 mg which was over about 4 weeks. ChatGPT said a derm would usually take 6-8 weeks to reach that dose if at all.

 

[Wolfgang Mayhem]

Thanks for sharing. How long did it take for it to clear up? Have you cycled again since?

Honestly, it’s been years so I’m not entirely sure. It was only a few weeks though. I knew I didn’t want to run it long or dosed high because of how harsh it is, so I stopped as soon as I cleared up. No issues since and I’ve run a lot of gear since then lol. I’m guesstimating and probably off a little, but I think it’s been like 20 years or so.

 

[Ghoul]

Thanks for confirming. It's weird, my dry lips and nose seem to have calmed a bit but my hands just flared up to compensate lol.



220 lbs.

Here you go, straight from the National Guidelines:

Isotretinoin - StatPearls - NCBI Bookshelf

(“Trunk involvement”, ie, back, chest, shoulder acne, is the key indication for the higher end of the dose range)

 

[adrenalytic]

Here you go, straight from the National Guidelines:

View attachment 370123

Isotretinoin - StatPearls - NCBI Bookshelf

(“Trunk involvement”, ie, back, chest, shoulder acne, is the key indication for the higher end of the dose range)

View attachment 370124

thanks. So I was probably just too aggressive in raising the dose. I was following your 5 day rule but that probably isn't across the board for everyone especially since I have pre-existing eczema. Gonna hold at 80 for a while till hands clear up.

 

[Ghoul]

thanks. So I was probably just too aggressive in raising the dose. I was following your 5 day rule but that probably isn't across the board for everyone especially since I have pre-existing eczema. Gonna hold at 80 for a while till hands clear up.

Yeah I mean the idea here is that 2mg/day is the absolute ceiling. You decide what’s tolerable, and unlike waiting 6 weeks to see a Derm for a dose adjustment, the beauty of “self directed treatment” is that you decide what you’re willing to put up with and can make the change immediately.

Although I titrated up pretty fast, I was willing to deal with the very flakey skin stage, for instance, once I hit 2mg / kg (180mg for me), I couldn’t hold it for long, and decided to extend my finish date by 3 weeks so I could “climb down” in doses and take it easy. By the way, when you start you going back down, sides drop off fast, even though the doses are still high. 140mg on the climb down, was a lot easier than 80mg on the way up.

 

[2ndchancesNK]

thanks. So I was probably just too aggressive in raising the dose. I was following your 5 day rule but that probably isn't across the board for everyone especially since I have pre-existing eczema. Gonna hold at 80 for a while till hands clear up.

Smart move, bro. I agree quite a bit with @Ghoul here. Climbing in doses is such a bitch, but when you go down it almost feels like you’re not even taking anything in comparison.

 

[k710]

My derms protocol was going to be start at 20mg and get to 80mg as quick as possible to shorten treatment duration. Approved and paid for by health insurance too... and those guys dont like to pay for shit..

So no ChatGPT, its not an absurd dose you twat. I hope you read this and update your isotreiton information sources.. Maybe read all of Ghoul's posts while your at it lol