Accutane permanent cure?

Testosterone makes your skin oily. That oil feeds bacteria, which causes acne. Rather than doxycycline or accutane, manage the oil and bacteria with hygiene:

✅ Wash your sheets weekly (twice if you’re on heavy PEDs). Dirty pillowcases are one of the top causes of acne.

✅ Wash your towel regularly. Don't let it become a source of bacteria and oil that causes breakouts. Make sure it hangs spread out to dry, don't let it touch the floor or bench. If fighting acne, a towel shouldn't be used more than twice before washing. When the acne is really bad, you may only be able to use it once. If you're not putting your towels in a dryer on high heat, then add a bit of bleach to the wash to kill off bacteria.

✅ Don’t over-dry your skin. Harsh cleansers can make your skin produce even more oil. Use gentle products: Dove Men’s Body Wash for your body, Cetaphil for your face. Wash your face twice daily. Moisturizer isn't needed.

Why I would advise against Doxycycline:
This specific antibiotic will kill off the bacteria and enzymes in your intestinal track. Want to become lactose intolerant and develop of bunch of food intolerances? This is a fast track to get there.

Why I would advise against Accutane:
Back in 1999, at 22, I suddenly got cystic acne. These aren’t your normal pimples—they’re painful, red, swollen bumps that never come to a head. I never had more than one at a time, but each needed a cortisone shot. It sucked.

After trying doxycycline and the usual meds, I did the standard 4-month Accutane course. It “works permanently” for most acne—but here’s the truth: it’s not worth it for everyone. Here was my experience:
  1. Emotions went wild. I’ve always been even-keeled, but during Accutane, I had horrifying, violent suicidal thoughts. ("Thoughts of suicide" is an actual listed side effect, but I had no idea that it was exactly what it.) They were graphic, vivid, bloody, and terrifying. I didn’t tell my doctor because I’d have been pulled off immediately. There’s also a risk of lasting depression. If you have any emotional instability, stay away.
  2. Your skin will hate you. Full-body peeling, cracking, dryness. It’s intense.
  3. Long-term dryness. I haven’t had a pimple since—but now my skin is so dry I have to moisturize constantly, not for fun but to avoid chafing and itching from dryness.
 
Testosterone makes your skin oily. That oil feeds bacteria, which causes acne. Rather than doxycycline or accutane, manage the oil and bacteria with hygiene:

✅ Wash your sheets weekly (twice if you’re on heavy PEDs). Dirty pillowcases are one of the top causes of acne.

✅ Wash your towel regularly. Don't let it become a source of bacteria and oil that causes breakouts. Make sure it hangs spread out to dry, don't let it touch the floor or bench. If fighting acne, a towel shouldn't be used more than twice before washing. When the acne is really bad, you may only be able to use it once. If you're not putting your towels in a dryer on high heat, then add a bit of bleach to the wash to kill off bacteria.

✅ Don’t over-dry your skin. Harsh cleansers can make your skin produce even more oil. Use gentle products: Dove Men’s Body Wash for your body, Cetaphil for your face. Wash your face twice daily. Moisturizer isn't needed.

Why I would advise against Doxycycline:
This specific antibiotic will kill off the bacteria and enzymes in your intestinal track. Want to become lactose intolerant and develop of bunch of food intolerances? This is a fast track to get there.

Why I would advise against Accutane:
Back in 1999, at 22, I suddenly got cystic acne. These aren’t your normal pimples—they’re painful, red, swollen bumps that never come to a head. I never had more than one at a time, but each needed a cortisone shot. It sucked.

After trying doxycycline and the usual meds, I did the standard 4-month Accutane course. It “works permanently” for most acne—but here’s the truth: it’s not worth it for everyone. Here was my experience:
  1. Emotions went wild. I’ve always been even-keeled, but during Accutane, I had horrifying, violent suicidal thoughts. ("Thoughts of suicide" is an actual listed side effect, but I had no idea that it was exactly what it.) They were graphic, vivid, bloody, and terrifying. I didn’t tell my doctor because I’d have been pulled off immediately. There’s also a risk of lasting depression. If you have any emotional instability, stay away.
  2. Your skin will hate you. Full-body peeling, cracking, dryness. It’s intense.
  3. Long-term dryness. I haven’t had a pimple since—but now my skin is so dry I have to moisturize constantly, not for fun but to avoid chafing and itching from dryness.

Uh oh. You don't know what you just started.
 
Testosterone makes your skin oily. That oil feeds bacteria, which causes acne. Rather than doxycycline or accutane, manage the oil and bacteria with hygiene:

✅ Wash your sheets weekly (twice if you’re on heavy PEDs). Dirty pillowcases are one of the top causes of acne.

✅ Wash your towel regularly. Don't let it become a source of bacteria and oil that causes breakouts. Make sure it hangs spread out to dry, don't let it touch the floor or bench. If fighting acne, a towel shouldn't be used more than twice before washing. When the acne is really bad, you may only be able to use it once. If you're not putting your towels in a dryer on high heat, then add a bit of bleach to the wash to kill off bacteria.

✅ Don’t over-dry your skin. Harsh cleansers can make your skin produce even more oil. Use gentle products: Dove Men’s Body Wash for your body, Cetaphil for your face. Wash your face twice daily. Moisturizer isn't needed.

Why I would advise against Doxycycline:
This specific antibiotic will kill off the bacteria and enzymes in your intestinal track. Want to become lactose intolerant and develop of bunch of food intolerances? This is a fast track to get there.

Why I would advise against Accutane:
Back in 1999, at 22, I suddenly got cystic acne. These aren’t your normal pimples—they’re painful, red, swollen bumps that never come to a head. I never had more than one at a time, but each needed a cortisone shot. It sucked.

After trying doxycycline and the usual meds, I did the standard 4-month Accutane course. It “works permanently” for most acne—but here’s the truth: it’s not worth it for everyone. Here was my experience:
  1. Emotions went wild. I’ve always been even-keeled, but during Accutane, I had horrifying, violent suicidal thoughts. ("Thoughts of suicide" is an actual listed side effect, but I had no idea that it was exactly what it.) They were graphic, vivid, bloody, and terrifying. I didn’t tell my doctor because I’d have been pulled off immediately. There’s also a risk of lasting depression. If you have any emotional instability, stay away.
  2. Your skin will hate you. Full-body peeling, cracking, dryness. It’s intense.
  3. Long-term dryness. I haven’t had a pimple since—but now my skin is so dry I have to moisturize constantly, not for fun but to avoid chafing and itching from dryness.
You can implement all of those things and still have acne. Your experience isn't an indicator of what other peoples experience with accutane will be.

There's always risks with anything. People have to decide for themselves if the benefits are worth it. For me, the risk of developing permanent acne scarring for life far outweighed a few uncomfortable months.
 
Testosterone makes your skin oily. That oil feeds bacteria, which causes acne. Rather than doxycycline or accutane, manage the oil and bacteria with hygiene:

✅ Wash your sheets weekly (twice if you’re on heavy PEDs). Dirty pillowcases are one of the top causes of acne.

✅ Wash your towel regularly. Don't let it become a source of bacteria and oil that causes breakouts. Make sure it hangs spread out to dry, don't let it touch the floor or bench. If fighting acne, a towel shouldn't be used more than twice before washing. When the acne is really bad, you may only be able to use it once. If you're not putting your towels in a dryer on high heat, then add a bit of bleach to the wash to kill off bacteria.

✅ Don’t over-dry your skin. Harsh cleansers can make your skin produce even more oil. Use gentle products: Dove Men’s Body Wash for your body, Cetaphil for your face. Wash your face twice daily. Moisturizer isn't needed.

Why I would advise against Doxycycline:
This specific antibiotic will kill off the bacteria and enzymes in your intestinal track. Want to become lactose intolerant and develop of bunch of food intolerances? This is a fast track to get there.

Why I would advise against Accutane:
Back in 1999, at 22, I suddenly got cystic acne. These aren’t your normal pimples—they’re painful, red, swollen bumps that never come to a head. I never had more than one at a time, but each needed a cortisone shot. It sucked.

After trying doxycycline and the usual meds, I did the standard 4-month Accutane course. It “works permanently” for most acne—but here’s the truth: it’s not worth it for everyone. Here was my experience:
  1. Emotions went wild. I’ve always been even-keeled, but during Accutane, I had horrifying, violent suicidal thoughts. ("Thoughts of suicide" is an actual listed side effect, but I had no idea that it was exactly what it.) They were graphic, vivid, bloody, and terrifying. I didn’t tell my doctor because I’d have been pulled off immediately. There’s also a risk of lasting depression. If you have any emotional instability, stay away.
  2. Your skin will hate you. Full-body peeling, cracking, dryness. It’s intense.
  3. Long-term dryness. I haven’t had a pimple since—but now my skin is so dry I have to moisturize constantly, not for fun but to avoid chafing and itching from dryness.
Wtf is this. This bot is shilling actual cures for acne. I've seen homeless people with clearer skin than mine. This is bullshit.
 
Wtf is this. This bot is shilling actual cures for acne. I've seen homeless people with clearer skin than mine. This is bullshit.
On a dating app, someone recently accused me of being AI generated. My pics were unedited, so that was almost as flattering.

You might find it challenging to string together more than a few sentences, but I throw together entire presentations in 20 minutes as part of my day to day.

The information I provided is mostly common sense and first hand personal knowledge, my sister is a dermatologist.

Thanks for the ego boost tho, bro.
 
You can implement all of those things and still have acne. Your experience isn't an indicator of what other peoples experience with accutane will be.

There's always risks with anything. People have to decide for themselves if the benefits are worth it. For me, the risk of developing permanent acne scarring for life far outweighed a few uncomfortable months.
This could be said for literally any advice on any post on the internet.

As for the risk of scarring, that's legit. But isn't jumping right into Accutane exactly like jumping onto gear without going to the gym? It's lazy in the same way. Or -- perhaps people don't realize the efforts required to fix it.

Guys usually have very questionable hygiene habits, they're just not situationally aware of it. A lot of guys wash their sheets once month at best.

All I'm saying here is, "go to the gym first".
 
This could be said for literally any advice on any post on the internet.

As for the risk of scarring, that's legit. But isn't jumping right into Accutane exactly like jumping onto gear without going to the gym? It's lazy in the same way. Or -- perhaps people don't realize the efforts required to fix it.
No, because if it doesn't work, which it likely won't if you are on PEDs, you're increasing the likelihood of permanent scarring.

Accutane doesn't have nearly the risk profile of gear, that's a false equivalency. It is an FDA approved drug permitted for children.
Guys usually have very questionable hygiene habits, they're just not situationally aware of it. A lot of guys wash their sheets once month at best.

All I'm saying here is, "go to the gym first".
I don't disagree, but you can walk and chew gum at the same time. It takes months for lifestyle changes to show results for acne, assuming that it even works.

This is like when somebody says they have a 150/90 blood pressure and the response is, "do cardio and eat better bro." Sure, those things might help, but they're going to take a lot of time to have any effect, all the while you are damaging your health.
 
No, because if it doesn't work, which it likely won't if you are on PEDs, you're increasing the likelihood of permanent scarring.

Accutane doesn't have nearly the risk profile of gear, that's a false equivalency. It is an FDA approved drug permitted for children.

I don't disagree, but you can walk and chew gum at the same time. It takes months for lifestyle changes to show results for acne, assuming that it even works.

This is like when somebody says they have a 150/90 blood pressure and the response is, "do cardio and eat better bro." Sure, those things might help, but they're going to take a lot of time to have any effect, all the while you are damaging your health.
I get where you're coming from, nobody wants scarring.

To be clear with where I'm coming from, my entire career (since 1994) has been in AI. I've worked in a lot of industries, but I worked for several big pharma companies for years using AI to identify trends in adverse events (aka "side effects") across medications and combinations of medications. I worked with committees made of doctors, pharmaDs, chemical engineers, biologists, and PR across lots of drugs for information exchange. It was a really fascinating (and horrifying) view into things I wish I could "unknow".

Also, my spouse is a PharmaD (with an BS in molecular and microbiology). He heads committees for the largest hospital system in the state reading studies and identifying new treatment protocols for various diseases and scenarios. We have a lot of discussions about these things -- but he has no knowledge of anything PED related. That's why I came hear to ask those questions from people who actually have experience with them.

In my current role as a director, I have 3 MDs, 2 PharmaDs, and an entire staff of people dedicated on eTMS, cTMS, Clinical Operations, and regulatory reporting of drug information to the EMEA and FDA.

When it comes to pharmacology, I have pretty good insight and access to an excellent knowledgeable degreed human sources literally and figuratively in arm's reach to answer questions.

Accutane doesn't have "risks that may occur", it has serious, likely permanent side effects that will occur, including liver damage to at least a mild extent. The only questions are: How severely will you be impacted by the side effects? And will they be permanent changes? (And it's only approved for as a last line of defense ages 12 and up, but it's unlikely you'll ever find a doctor or a situation where they would prescribe it to someone under 15.)

The FDA and EMEA approve a lot of things, including extremely toxic chemotherapy for children. That doesn't mean they're "safe", it means they're approved to do the job they were tested for and that they feel the side effects have been adequately identified and listed on the label. The assumption is not that the drug is "safe", it's that the patient and doctor will have a discussion about the side effects and the patient will decide whether to accept the risks before taking the drug. (Unfortunately, people don't understand this and often reap the consequences. I'm very lucky to have access to sources where I can have these candid discussions and make sure I'm always making informed decisions.)

With the exception of cystic acne, proper hygiene can generally clear regular acne up in 2-3 weeks. To reduce the risk of the the initial outbreak or severe acne and scarring, it would be a better plan to ensure the proper hygiene protocols were in place before starting a cycle. There are also some really good benzoyl peroxide body washes you can easily get a script for (but don't use them on your twig and berries).

I would treat Accutane, specifically, as the very last line of defense and would absolutely avoid it for long term use, even at a lower dosage.
 
Last edited:
I get where you're coming from, nobody wants scarring.

To be clear with where I'm coming from, my entire career (since 1994) has been in AI. I've worked in a lot of industries, but I worked for several big pharma companies for years using AI to identify trends in adverse events (aka "side effects") across medications and combinations of medications. I worked with committees made of doctors, pharmaDs, chemical engineers, biologists, and PR across lots of drugs for information exchange. It was a really fascinating (and horrifying) view into things I wish I could "unknow".

Also, my spouse is a PharmaD (with an BS in molecular and microbiology). He heads committees for the largest hospital system in the state reading studies and identifying new treatment protocols for various diseases and scenarios. We have a lot of discussions about these things -- but he has no knowledge of anything PED related. That's why I came hear to ask those questions from people who actually have experience with them.

In my current role as a director, I have 3 MDs, 2 PharmaDs, and an entire staff of people dedicated on eTMS, cTMS, Clinical Operations, and regulatory reporting of drug information to the EMEA and FDA.

When it comes to pharmacology, I have pretty good insight and access to an excellent knowledgeable degreed human sources literally and figuratively in arm's reach to answer questions.

Accutane doesn't have "risks that may occur", it has serious, likely permanent side effects that will occur, including liver damage to at least a mild extent. The only questions are: How severely will you be impacted by the side effects? And will they be permanent changes? (And it's only approved for as a last line of defense ages 12 and up, but it's unlikely you'll ever find a doctor or a situation where they would prescribe it to someone under 15.)

The FDA and EMEA approve a lot of things, including extremely toxic chemotherapy for children. That doesn't mean they're "safe", it means they're approved to do the job they were tested for and that they feel the side effects have been adequately identified and listed on the label. The assumption is not that the drug is "safe", it's that the patient and doctor will have a discussion about the side effects and the patient will decide whether to accept the risks before taking the drug. (Unfortunately, people don't understand this and often reap the consequences. I'm very lucky to have access to sources where I can have these candid discussions and make sure I'm always making informed decisions.)

With the exception of cystic acne, proper hygiene can generally clear regular acne up in 2-3 weeks. To reduce the risk of the the initial outbreak or severe acne and scarring, it would be a better plan to ensure the proper hygiene protocols were in place before starting a cycle. There are also some really good benzoyl peroxide body washes you can easily get a script for (but don't use them on your twig and berries).

I would treat Accutane, specifically, as the very last line of defense and would absolutely avoid it for long term use, even at a lower dosage.
Permanent liver damage from isotretinoin is exceptionally rare, as are permanent side effects in general. I'm not sure where you are seeing otherwise, but point me towards the research that shows that.

Comparing chemotherapy approval for children with cancer that are guaranteed to die without it to the treatment of acne is wild. I don't think I need to defend that any further.

Benzoyl peroxide is great and I use it in conjunction with accutane to control acne, but it can be up to 4 months before the full effects show. You will not clear moderate-severe acne in 2-3 weeks no matter what you do, even high dose accutane.
 
I get where you're coming from, nobody wants scarring.

To be clear with where I'm coming from, my entire career (since 1994) has been in AI. I've worked in a lot of industries, but I worked for several big pharma companies for years using AI to identify trends in adverse events (aka "side effects") across medications and combinations of medications. I worked with committees made of doctors, pharmaDs, chemical engineers, biologists, and PR across lots of drugs for information exchange. It was a really fascinating (and horrifying) view into things I wish I could "unknow".

Also, my spouse is a PharmaD (with an BS in molecular and microbiology). He heads committees for the largest hospital system in the state reading studies and identifying new treatment protocols for various diseases and scenarios. We have a lot of discussions about these things -- but he has no knowledge of anything PED related. That's why I came hear to ask those questions from people who actually have experience with them.

In my current role as a director, I have 3 MDs, 2 PharmaDs, and an entire staff of people dedicated on eTMS, cTMS, Clinical Operations, and regulatory reporting of drug information to the EMEA and FDA.

When it comes to pharmacology, I have pretty good insight and access to an excellent knowledgeable degreed human sources literally and figuratively in arm's reach to answer questions.

Accutane doesn't have "risks that may occur", it has serious, likely permanent side effects that will occur, including liver damage to at least a mild extent. The only questions are: How severely will you be impacted by the side effects? And will they be permanent changes? (And it's only approved for as a last line of defense ages 12 and up, but it's unlikely you'll ever find a doctor or a situation where they would prescribe it to someone under 15.)

The FDA and EMEA approve a lot of things, including extremely toxic chemotherapy for children. That doesn't mean they're "safe", it means they're approved to do the job they were tested for and that they feel the side effects have been adequately identified and listed on the label. The assumption is not that the drug is "safe", it's that the patient and doctor will have a discussion about the side effects and the patient will decide whether to accept the risks before taking the drug. (Unfortunately, people don't understand this and often reap the consequences. I'm very lucky to have access to sources where I can have these candid discussions and make sure I'm always making informed decisions.)

With the exception of cystic acne, proper hygiene can generally clear regular acne up in 2-3 weeks. To reduce the risk of the the initial outbreak or severe acne and scarring, it would be a better plan to ensure the proper hygiene protocols were in place before starting a cycle. There are also some really good benzoyl peroxide body washes you can easily get a script for (but don't use them on your twig and berries).

I would treat Accutane, specifically, as the very last line of defense and would absolutely avoid it for long term use, even at a lower dosage.

Imma save you a little bit of time typing for next time. No one here gives a shit about your credentials which may or may not be made up. You're judged by the content of your posts, not what you (or AI) cook up to try and impress us with so half of your TL;DR is a waste of time. Stick to verifiable facts. Save the fluff for your online dating profile.

As to the points that actually talk about Accutane, I'm not going to go through them all but I'll just say that androgen induced acne is not a fucking hygiene issue. You can shower 6 times a day and sleep in a hyperbaric chamber and still break out if you're sensitive to DHTs or your E2 gets fucked. Most guys are here to fix that. Go take that big brain and learn how constantly fluctuating androgens influence sebum production and pore size. You can even search this thread for a proper explanation.

I'm guessing @Ghoul is on vacation or something or he would have annihilated your argument by now.
 
Imma save you a little bit of time typing for next time. No one here gives a shit about your credentials which may or may not be made up. You're judged by the content of your posts, not what you (or AI) cook up to try and impress us with so half of your TL;DR is a waste of time. Stick to verifiable facts. Save the fluff for your online dating profile.

As to the points that actually talk about Accutane, I'm not going to go through them all but I'll just say that androgen induced acne is not a fucking hygiene issue. You can shower 6 times a day and sleep in a hyperbaric chamber and still break out if you're sensitive to DHTs or your E2 gets fucked. Most guys are here to fix that. Go take that big brain and learn how constantly fluctuating androgens influence sebum production and pore size. You can even search this thread for a proper explanation.

I'm guessing @Ghoul is on vacation or something or he would have annihilated your argument by now.
Valid point about credentials, anyone can claim anything on the internet.

But the facts here are very easily verifiable to anyone who knows how to use Google. Had they looked it up, they would've already known so clearly they didn't.

For reliable info re: Accutane, go directly to the FDA website. It's public info, though it might be a bit too much technical jargon for the layperson. You can find really great info and studies re: acne and Accutane on NIH.

Accutane is only indicated for cycstic acne.

For a laymen's understanding about acne, there's a decent explanation on the JAMA dermatology page

It's well known that fluctuating androgens (whether from PEDs or puberty or menstrual cycles) cause excess oil production, which feeds bacteria, which is the actual cause of acne.

1 + 1 + 1 still equals 3, my friend.

Take care of the oil and bacteria as outlined above and you'll likely solve the problem. But you won't know unless you try first. ;) Or skip the effort and jump right into accepting the damage and risk of Accutane. AKA - skipping the gym. You do you.

As I said in my first post, I developed cystic acne in my early 20s - no relation to hormones or anything else and I wasn't able to resolve it with any of the above steps. That's why I had to take Accutane.
 
Valid point about credentials, anyone can claim anything on the internet.

But the facts here are very easily verifiable to anyone who knows how to use Google. Had they looked it up, they would've already known so clearly they didn't.

For reliable info re: Accutane, go directly to the FDA website. It's public info, though it might be a bit too much technical jargon for the layperson. You can find really great info and studies re: acne and Accutane on NIH.

Accutane is only indicated for cycstic acne.

For a laymen's understanding about acne, there's a decent explanation on the JAMA dermatology page

It's well known that fluctuating androgens (whether from PEDs or puberty or menstrual cycles) cause excess oil production, which feeds bacteria, which is the actual cause of acne.

1 + 1 + 1 still equals 3, my friend.

Take care of the oil and bacteria as outlined above and you'll likely solve the problem. But you won't know unless you try first. ;) Or skip the effort and jump right into accepting the damage and risk of Accutane. AKA - skipping the gym. You do you.

As I said in my first post, I developed cystic acne in my early 20s - no relation to hormones or anything else and I wasn't able to resolve it with any of the above steps. That's why I had to take Accutane.
Stop giving advice about steroid induced acne, you don't know shit about it. You said you came here to learn about steroids. Shut your trap and learn.
 
Stop giving advice about steroid induced acne, you don't know shit about it. You said you came here to learn about steroids. Shut your trap and learn.
I get it man. Nobody wants to hear their baby is ugly, not everyone passed Heatlh or 7th grade science, and a lot of guys don't wash their asshole with soap and water. You do you.

But you're the boss of no one, so it's probably best for you to disagree and move along. Or stay and rage like a hot trenny mess. IDC.
 
Back
Top