Update: My acne was getting really bad, for me anyways. I had a bunch on my chest and back all of which were cystic and actually very painful. I decided to start accutain, today is day 5 of 20mg ED. My skin is clearing up very quickly, I would say that by the second or third day all the cystic acne on my chest was calmed down, no longer hurt, and was healing. Today, day 5, only a few of the more stubborn ones are still there. Side effects: Headache for a couple hours after taking it, goes away after a while, or if I take a Tylenol. Now I gotta figure if I want to run a full cycle of this, or step off after I heal and see if it comes back. To the user who asked about labs, yeah I ran labs. I cant find my labs while I was blasting, my previous values when I first was trying to get dosage right was 1,500 T, 77 Estridol. Since then I dropped it by 50mgs, and switched from once, to twice a week split in half. Im thinking I am sitting around 1,000 test, not sure Estridol, but should be lower. Im due for another lab though soon.