Another REGAINING Fertility Log after 9 years of AAS

So here’s my SA results after 75 days off test only 1 week in with HMG.

Results are unfortunately not too good but that’s expected after 9 years of steroids

I have another SA august 7th and this time I’ll do it directly at the lab instead of at home and then driving.
Thanks for sharing. It's unfortunate that you're count is still low, but at least it's not zero! It means that you're not just spinning your wheels trying to make a baby every month. It would be helpful to know exactly how many sperm you have, though.
 
Thanks for sharing. It's unfortunate that you're count is still low, but at least it's not zero! It means that you're not just spinning your wheels trying to make a baby every month. It would be helpful to know exactly how many sperm you have, though.
Yeah I have no idea why they didn't include total count... next SA is in 5 weeks so I'm hoping the numbers goes up a lot.
 
Well we just did a test this morning and no luck, negative.
I'm not sure I had enough sperms to make it work.

Protocol update : I will follow recommendations of dropping clomid and just use HCG 2500IU EOD + HMG 75IU EOD.

Crossing fingers for next month
 
Well we just did a test this morning and no luck, negative.
I'm not sure I had enough sperms to make it work.

Protocol update : I will follow recommendations of dropping clomid and just use HCG 2500IU EOD + HMG 75IU EOD.

Crossing fingers for next month

View: https://www.youtube.com/live/6x67Lbfc4AQ?feature=share


Check the time stamp, they share their current protocols. Chase irons actually was successful in knocking her lady even with lesser injection frequency.

Good luck brother.
 
Well we just did a test this morning and no luck, negative.
I'm not sure I had enough sperms to make it work.

Protocol update : I will follow recommendations of dropping clomid and just use HCG 2500IU EOD + HMG 75IU EOD.

Crossing fingers for next month
I think you are better off with just dropping the hcg+hmg completely and just take low dose Clomid for the next 8 weeks. It will likely be the better option in your case. The point is if you are off of exogenous testosterone and still take hcg+hmg your own testosterone production will not be not fully working. And you already went off of everything, didn’t you? So low dose Clomid is your best bet here to get your lady pregnant asap.

Just imho.
 
I think you are better off with just dropping the hcg+hmg completely and just take low dose Clomid for the next 8 weeks. It will likely be the better option in your case. The point is if you are off of exogenous testosterone and still take hcg+hmg your own testosterone production will not be not fully working. And you already went off of everything, didn’t you? So low dose Clomid is your best bet here to get your lady pregnant asap.

Just imho.
What dosage would you suggest for the clomid?

Just got bloods done and doc only told me my free T was 44? She very clueless and told me normal range is between 7-33.

I’m only going to be able to look at bloods results in 2-3 weeks
 
I think you are better off with just dropping the hcg+hmg completely and just take low dose Clomid for the next 8 weeks. It will likely be the better option in your case. The point is if you are off of exogenous testosterone and still take hcg+hmg your own testosterone production will not be not fully working. And you already went off of everything, didn’t you? So low dose Clomid is your best bet here to get your lady pregnant asap.

Just imho.
I agree with this. Hcg and hmg should be used while on trt. Clomid is better while completely off. Not to mention it’s a fuck ton cheaper. It will take a WHILE though. I’d plan on 6 months to a year. Just an fyi. We had our first child while I stayed on 100mg test and using hcg/FSH. Both from a compounding pharmacy in the US. Took about 8-10 months. I’m currently running 75mg of hmg 3x a week during blast to prime the pump, so to speak, in case we try again this winter. I’m sourcing it from QSC. It’s very affordable through them. Hopefully it’s legit.
 
What dosage would you suggest for the clomid?
12,5mg every day for 4-8 weeks. You can do less if you dont feel well on it. Usually they come in 25mg tablets so you can split them up in either 2 or 4 parts depending on side effects and how you feel. For some it can make a drastic difference if they take it in the evening before sleep in regards to sides.
 
I've checked online and found various studies that linked this. I'd like to know your opinions on this vid/study because in the research it says to basically stop testosterone first. if azoospermia/oligospermia take HCG 2000IU EOD + Clomid 50mg EOD. If after 3 months still no/low sperm then add FSH with HCG and stop clomid. If fertility is my primary goal don't guys think it's going to be fast with HCG/HMG ?


View: https://www.youtube.com/watch?v=ANyMNsfZiqA&ab_channel=SSMR
 

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I think you are better off with just dropping the hcg+hmg completely and just take low dose Clomid for the next 8 weeks. It will likely be the better option in your case. The point is if you are off of exogenous testosterone and still take hcg+hmg your own testosterone production will not be not fully working. And you already went off of everything, didn’t you? So low dose Clomid is your best bet here to get your lady pregnant asap.

Just imho.
Confused why you are saying clomid would work more quickly than HCG + FHS/HMG? Just coming off testosterone doesnt mean his body his ready for spermatogenesis. If his goal is to obtain pregnancy ASAP then clomid wont do that for him if his intra-testicular testosterone has not reached a level yet that is able to promote spermatogenesis. That would happen with monitoring of blood work to check his endogenous T and gonadotropin production, which can be expedited with use of HCG throughout cycling/TRT and during post-cycle to prime leydig cells. But looking through his previous posts it doesnt seem like he provided any of that, so Im assuming he hasn't. It sounds like his best bet is to obtain real HCG/HMG and follow the protocol above, especially if money isnt an issue. If it is, then HCG + clomid should be fine, but it'll likely take much longer as he wont be bypassing recovery of the HPTA axis by using gonadotropins to directly stimulate leydig cells and Sertoli cells to promote spermatogenesis. If there is any literature you have come across that shows clomid being a better option for him to obtain pregnancy more quickly please share, as I genuinely want to know and it would change the understanding I thought I had about recovery/fertility and also make it much much cheaper moving forward

Personally I would consider just adding in the low dose clomid to the HCG/FSH. There is a theoretical risk of exogenous FSH decreasing endogenous FSH production through negative feedback loop via inhibin however this is very unlikely. Bi-weekly or EOD FSH administration is unlikely to raise serum levels high enough to cause a negative feedback. Even in one of the videos posted above, vigerous talk about performing daily FSH administration and serum tests showed he was mid-normal range. With EOD dosing he was low-mid range, both wouldnt be high enough to stop endogenous production. LH also does not have a negative feedback to the pituitary, that is occurs downstream via testosterone. Taking clomid could theoretically minimize risk of negative feedback loop and increase endogenous FSH production at the same time of using exogenous FSH.

I think he's further behind that he really is based on taking some bunk products. Id assume everything from that supplier is bunk until I had testing done to prove otherwise and move forward as if I came off but never did a PCT after being on for 9 years...
 
Confused why you are saying clomid would work more quickly than HCG + FHS/HMG? Just coming off testosterone doesnt mean his body his ready for spermatogenesis. If his goal is to obtain pregnancy ASAP then clomid wont do that for him if his intra-testicular testosterone has not reached a level yet that is able to promote spermatogenesis. That would happen with monitoring of blood work to check his endogenous T and gonadotropin production, which can be expedited with use of HCG throughout cycling/TRT and during post-cycle to prime leydig cells. But looking through his previous posts it doesnt seem like he provided any of that, so Im assuming he hasn't. It sounds like his best bet is to obtain real HCG/HMG and follow the protocol above, especially if money isnt an issue. If it is, then HCG + clomid should be fine, but it'll likely take much longer as he wont be bypassing recovery of the HPTA axis by using gonadotropins to directly stimulate leydig cells and Sertoli cells to promote spermatogenesis. If there is any literature you have come across that shows clomid being a better option for him to obtain pregnancy more quickly please share, as I genuinely want to know and it would change the understanding I thought I had about recovery/fertility and also make it much much cheaper moving forward

Personally I would consider just adding in the low dose clomid to the HCG/FSH. There is a theoretical risk of exogenous FSH decreasing endogenous FSH production through negative feedback loop via inhibin however this is very unlikely. Bi-weekly or EOD FSH administration is unlikely to raise serum levels high enough to cause a negative feedback. Even in one of the videos posted above, vigerous talk about performing daily FSH administration and serum tests showed he was mid-normal range. With EOD dosing he was low-mid range, both wouldnt be high enough to stop endogenous production. LH also does not have a negative feedback to the pituitary, that is occurs downstream via testosterone. Taking clomid could theoretically minimize risk of negative feedback loop and increase endogenous FSH production at the same time of using exogenous FSH.

I think he's further behind that he really is based on taking some bunk products. Id assume everything from that supplier is bunk until I had testing done to prove otherwise and move forward as if I came off but never did a PCT after being on for 9 years...
HCG and hmg can interfere with bis body's natural hormone production, he just came off of everything and I have seen people getting better results by just taking Clomid alone (that does not interfere with his natural production) than with hcg+hmg while trying to recovery his hpta.

Why are you even asking me if you know the risk yourself, as you have pointed it out. And it's not just theoretical, hcg and hmg will give a negative feedback loop on his hpta and so his body will not fully recover or in some cases not even recover at all.
 
I also believe that my dutasteride + finasteride combo nuking my DHT wasn't helping my chance to conceive. Dropped dutasteride 5 weeks ago and finasteride 2 weeks ago.

Held off dropping them for a long time because I feared going bald but now my priority is to make sure I do everything I can to improve my numbers.

This probably wasn't making me azoospermia but I believe it made my count lower.

Found various studies where sperm count was affected.

GF said it will be a sad christmas if she's not pregnant by december. This is very depressing on my part but she's been very supportive and hopeful in the last weeks.

thank you everyone in the thread that gave me opinions/knowledge.

I'll reupdate when I get a new SA in 3 weeks.
 
HCG and hmg can interfere with bis body's natural hormone production, he just came off of everything and I have seen people getting better results by just taking Clomid alone (that does not interfere with his natural production) than with hcg+hmg while trying to recovery his hpta.

Why are you even asking me if you know the risk yourself, as you have pointed it out. And it's not just theoretical, hcg and hmg will give a negative feedback loop on his hpta and so his body will not fully recover or in some cases not even recover at all.
I wasn't trying to bash you, just asking if there was literature you came across. Meso is a place where many come for knowledge or help and if I learn something new, great. That being said, the people you have seen experience with Clomid is anecdotal, and there are too many variables that could have affected it. Simplist being HCG/HMG is more frequently faked than clomid due to cost. Regardless, HCG/FSH negatively feedbacking on his HPTA and affecting his recovery is theoretical, there is no absolute that it will and no literature to support that it will, hence why I asked my question in the first place.

I have never come across anything showing elevated FSH negatively feedbacking on the HPTA axis in vivo. Even with daily dosing of FSH, serum levels don't seem to be elevated enough to have that happen. No study has looked at inhibin levels following FSH administration in testosterone-induced infertility or FSH level needed to result in inhibin negative feedback. Only has been tested in PCOS women, which is a pathologic process in itself. And HCG shouldn't interfere with his normal hormone production unless it is resulted in him producing so much testosterone that it feedback negatively on the HPTA, which is doubtful. Risk of desensitization would be at doses and durations much longer and was mostly described from in vitro or mice/rat studies
 
I have never come across anything showing elevated FSH negatively feedbacking on the HPTA axis in vivo. Even with daily dosing of FSH, serum levels don't seem to be elevated enough to have that happen. No study has looked at inhibin levels following FSH administration in testosterone-induced infertility or FSH level needed to result in inhibin negative feedback.
I will have a look into it at the weekend but what we know from the literature so far is that every hormone in human body is underlying a feedback loop mechanism by which the body is up or downregulating either the hormone itself and/or other hormones as well. This is common sense and seen with literally any hormone that I know of, and this also applies for LH/FSH and its mimics like hcg/hmg.
 
I will have a look into it at the weekend but what we know from the literature so far is that every hormone in human body is underlying a feedback loop mechanism by which the body is up or downregulating either the hormone itself and/or other hormones as well. This is common sense and seen with literally any hormone that I know of, and this also applies for LH/FSH and its mimics like hcg/hmg.
I completely agree with you. Also, need to consider that all hormones and gonadotropins do not affect the axis to the same magnitude. Testosterone is the primary inhibitor of the pituitary for both LH and FSH release. If he were still on TRT, adding Clomid is counterintuitive as he would be hoping for the pituitary to release FSH/LH but still has supraphysiologic T levels causing inhibition.

He stopped testosterone and removed the inhibition on the pituitary, but even if it begins secreting LH/FSH he needs to wait for intratesticular testosterone to reach levels adequate enough to maintain spermatogenesis. Taking Clomid and HCG is adding an upstream step in the axis pathway and hoping his pituitary is functioning properly. HCG/HMG bypasses the pituitary and will act downstream, directly on the testes to begin spermatogenesis. There is no way physiologically that Clomid/HCG will result in improved sperm parameters faster than HCG/Clomid, that is common sense as well.
 
Relevant question.

If your LH and FSH is 0. Does that mean you have azoospermia?
 
Quick little update

It's now been 4 months since my last test pin. I think my body is recovering well... I've lost a ton of muscle mass but that's just because I don't train really hard anymore. I feel suprisingly great. My libido has returned lately... I can probably link that with me stopping finasteride.

I also took a YO sperm home test and now I can see swimmers moving in the video. This was not the case about a month ago. It says I'm still under 6 millions per ML but it's still progress.

Going on a vacation cruise soon so had to move the real SA to august 28th. I would be disapointed if I'm still under 10/15 mil per ML with low motility.

here's the yo sperm test video. (I know it's not a lot a sperms but I had none in the past 3 tests )

I'll retake a test in a few weeks to see If it's improving

I'm hopeful that the GF gets pregnant before Christmas!

Cheers everyone.
 

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Quick little update

It's now been 4 months since my last test pin. I think my body is recovering well... I've lost a ton of muscle mass but that's just because I don't train really hard anymore. I feel suprisingly great. My libido has returned lately... I can probably link that with me stopping finasteride.

I also took a YO sperm home test and now I can see swimmers moving in the video. This was not the case about a month ago. It says I'm still under 6 millions per ML but it's still progress.

Going on a vacation cruise soon so had to move the real SA to august 28th. I would be disapointed if I'm still under 10/15 mil per ML with low motility.

here's the yo sperm test video. (I know it's not a lot a sperms but I had none in the past 3 tests )

I'll retake a test in a few weeks to see If it's improving

I'm hopeful that the GF gets pregnant before Christmas!

Cheers everyone.
Don’t be disappointed. You’re clearly making progress but don’t be surprised if you are still a ways away, looking at your video. Keep at it!
 
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