ARA-290

[Here2Learn]

Just thought I would share my experience running ara-290. I originally thought it would make a great option so I could cycle off Kpv and still have some inflammation control. KPV has been stellar in reducing pain and inflammation but I figure it would be good to run in cycles.

Ara-290 wouldn’t qualify as a replacement imo, it does take weeks to really take effect though. All the sudden I noticed an area in my leg that has some nerve damage not having the odd sensations anymore. I had slight swelling there, blood flow felt lacking and it was either hotter or colder than the skin around it. Now it feels closer to the rest of my leg. I did have sparkling feeling in my fingers and odd places off and on the first couple of weeks it started. This peptide is known to be good for nerve pain and I will say it is worth a try for anyone having an issue.



ARA-290, also known as cibinetide, has received orphan drug designations from the FDA for two indications: sarcoidosis and the treatment of neuropathic pain in patients with sarcoidosis. Additionally, it has received orphan drug designation from the EMA for the prevention of graft loss in pancreatic islet cell transplants

 

[LGOP528]

I picked up a kit of ARA-290 a long time ago but I could not get it to reconstitute. Tried a few different PH bac but it never worked. Did you have to do anything different to mix it?

How long and what dosage of KPV did you run?

Thanks for the feedback, there is not a lot of information on these two peptides on here.

 

[Here2Learn]

I picked up a kit of ARA-290 a long time ago but I could not get it to reconstitute. Tried a few different PH bac but it never worked. Did you have to do anything different to mix it?

How long and what dosage of KPV did you run?

Thanks for the feedback, there is not a lot of information on these two peptides on here.

I’ve had no issues reconstituting and use Hospira bac, doesn’t take anything special.

I run Kpv at 500mcg daily, the how long part is where my question has been. A safe bet is 6-8 weeks but I would love to stay on it. I’ve done some different updates on my experience with kpv, it is one of my favorite peptides.

 

[KOArtist]

I’m highly interested right now due to having some unexplained numb toes lately (neuropathy?), it’s supposed to help that too.

 

[Here2Learn]

I’m highly interested right now due to having some unexplained numb toes lately (neuropathy?), it’s supposed to help that too.

Yes, I am pretty sure that is one of the main functions with the fda approval. It has earned a spot in my don’t run out list for sure.

 

[Motojager]

I picked up a kit of ARA-290 a long time ago but I could not get it to reconstitute. Tried a few different PH bac but it never worked. Did you have to do anything different to mix it?

How long and what dosage of KPV did you run?

Thanks for the feedback, there is not a lot of information on these two peptides on here.

I put .25 ml of sodium bicarbonate in with the hospira bac water. Allows it to mix perfectly. Without the SB doesn’t mix no matter how long it sits.I take 4mg daily for dose. Neuropathy pain is greatly reduced. Was able to drop Cymbalta with the ARA

 

[songsofpyramids]

and still have some inflammation control

Are you on glp1 already? Sema has been by far the best drug for inflammation I have ever taken.

 

[Ghoul]

I’m highly interested right now due to having some unexplained numb toes lately (neuropathy?), it’s supposed to help that too.

Does cold trigger or worsen it?

I had toes start going numb randomly and it took years to track down what turned out to be a relatively simple fix.

 

[KOArtist]

Does cold trigger or worsen it?

I had toes start going numb randomly and it took years to track down what turned out to be a relatively simple fix.

I’m pretty sure it would aggravate it, but I live in AZ so not much exposure! What ended up being the issue? I have low iron levels for some mystery reason and thought it might be that but I’m stumped.

 

[Here2Learn]

Are you on glp1 already? Sema has been by far the best drug for inflammation I have ever taken.

Sema was absolutely the best for my inflammation too but I couldn’t handle the exhaustion I got.

 

[songsofpyramids]

Sema was absolutely the best for my inflammation too but I couldn’t handle the exhaustion I got.

Have you tried tirz or Reta? I have heard people suffer the exhaustion less on tirz, and I believe Reta is designed to give you energy. Both are even better at controlling systemic inflammation than sema as well. I count myself very lucky that sema doesn’t hit me with any side effects.

 

[LGOP528]

Have you tried tirz or Reta? I have heard people suffer the exhaustion less on tirz, and I believe Reta is designed to give you energy. Both are even better at controlling systemic inflammation than sema as well. I count myself very lucky that sema doesn’t hit me with any side effects.

Where did you see that tirz and reta were better for inflammation?

 

[songsofpyramids]

Where did you see that tirz and reta were better for inflammation?

A user on here posted an excerpt from a meta study that compared crp reduction for all 3 and it went Reta > Tirz > Sema in terms of how quickly and drastically crp was reduced. That said, there are users on here and anecdotal reports elsewhere that sema was best for reducing inflammation from people who have tried all of them (I have only done sema). I did some searching to find the excerpt but it was awhile ago and I can’t remember what thread it was in.

 

[LGOP528]

A user on here posted an excerpt from a meta study that compared crp reduction for all 3 and it went Reta > Tirz > Sema in terms of how quickly and drastically crp was reduced. That said, there are users on here and anecdotal reports elsewhere that sema was best for reducing inflammation from people who have tried all of them (I have only done sema). I did some searching to find the excerpt but it was awhile ago and I can’t remember what thread it was in.

For me, sema seems to work better for inflammation. Just got some blood work last week and my crp was only 2.1. This was with an infected ear and sinuses, severe spinal stenosis, and no NSAIDs because I could not have them for prp shots. I was pretty shocked. I have had higher crp’s just training hard on reta.

I just switched from Reta to sema because I saw a thread saying that GLP-1 is what lowers inflammation. Makes sense because sema is only GLP-1. Then it broke it down comparing the other two. Reta had more GLP-1 than tirz.

Once I unfuck my injuries, I will go back to Reta though. Sema destroys my cardio.

 

[songsofpyramids]

Once I unfuck my injuries, I will go back to Reta though. Sema destroys my cardio.

Super interesting. I’ve noticed no performance negative from sema but I’m only using .6mg and am purposefully avoiding hitting a dose that causes weight loss. I have heard that Reta is the best for performance from a few people now.

 

[Here2Learn]

A user on here posted an excerpt from a meta study that compared crp reduction for all 3 and it went Reta > Tirz > Sema in terms of how quickly and drastically crp was reduced. That said, there are users on here and anecdotal reports elsewhere that sema was best for reducing inflammation from people who have tried all of them (I have only done sema). I did some searching to find the excerpt but it was awhile ago and I can’t remember what thread it was in.

My experience was the exact opposite, sema was by far the best at inflammation reduction then Tirz and then Reta.