Yeah, tell that to the millions of patients on long term/permanent glucocorticoid therapy. More are on long term therapy than short term therapy. Go dig for the statistics. They are out there.
Exactly. You nailed it on the head.
They are on LONG TERM THERAPY. This causes
dependence. Although if there are that many (which I doubt), then why does
this MEDLINE search study only find 26 possible and 22 confirmed case studies of glucocorticoid (GC) dependence? That does not line up with "millions of patients" on long term GC therapy. Also here, "
Dependence is unusal" on glucocorticoids.
But wait, there's more: This study found in the UK (note, release date 2000) only identified 244,235 oral GC users in their General Practice Research Database (GPRD--not to be confused with GDPR).
Within that population:
- 103,008 only received one prescription during follow up.
- 37,424 received two scripts
- 103,803 received 3 or more.
Prednisolone was most frequently prescribed. This is basically a prodrug for prednisone; it get converted into prednisone in the liver.
Another study in Denmark, found 926,314 GC users from 1999-2014.
With those numbers and info on number of scripts received and approximated equivalent duration of usage. This does NOT add up to millions of long term GC users.
Please do research before you spout out information.