Aromatase Inhibitors Fix the Number but Break the System, open discussion.

[bananafeet]

This is something I've been wondering about, why no short esters?
From pharma, it's easy to purchase e2V and e2C amps/vials.

The follow raws are all insanely easy to get
e2base
e2cyp
e2e
e2v
e2undec

There's e2ace, seemly not popular and difficult to get, used in some non-inj pharma products.

Then there's e2b which apparently, is cheap and very easy to get.

Estradiol benzoate - Wikipedia

en.wikipedia.org

It was the first estrogen to be used in humans.
No longer popular now, but still available for pets -- which means you can still buy it, pet pharma. Seems to act pretty quick if you ask me.

View attachment 376164

Raws don't cost much either.

200mg, 55bucks, from an actual legit non-UGL lab.
At 1mg/week, that's 200 weeks worth.

https://www.sigmaaldrich.com/US/en/product/sigma/e8515

How i invision Photon:

 

[AlexDavis43]

For males, there's a diurnal rhythm for T, which may be why some people just feel better with daily shots. Peaks in the morning, dips at night. I assumed it was the same for e2 but apparently I'm wrong.

You see here, fluctuations in T, morning v night.
Easy to mimic, using a daily short + long ester mix.
View attachment 376264

But for e2, minor variation.
View attachment 376265

Looks like boring, slow steady is probably the way to go.
So who's up for some e2 undecanoate

The Effect of Diurnal Variation on Clinical Measurement of Serum Testosterone and Other Sex Hormone Levels in Men - PMC

Context: Although diurnal variation of testosterone and other hormones in men has been well documented, the effect of this variation on sampling during typical clinic hours has not been examined. Objective: Our objective was to examine temporal ...

pmc.ncbi.nlm.nih.gov

In some places like UK, sustanon is more commonly prescribed for TRT than Test E/C

It doesn't mimic natural circadian fluctuations exactly, but at least you get some variations (talking strictly TRT, not TRT+ or blasting)

 

[BALLISTIC]

So who's up for some e2 undecanoate

Me for sure, haha

 

[BALLISTIC]

In some places like UK, sustanon is more commonly prescribed for TRT than Test E/C

It doesn't mimic natural circadian fluctuations exactly, but at least you get some variations (talking strictly TRT, not TRT+ or blasting)

I like sustanon. I know some have a love hate relationship with it. But I have never had an issue with the combination esters. In my early years every blast consisted of sustanon. Even with the combination esters I've always resorted to daily dosing. I noticed I had great results.

 

[BALLISTIC]

I found some stuff:

https://medlineplus.gov/download/genetics/gene/cyp19a1.pdf

Aromatase deficiency - Wikipedia

en.wikipedia.org

"Low estrogen is also thought to be linked to abnormal lipid profile and hyperinsulinemia in men, though the mechanism is unknown."

I wonder if you could check if you've got the gene.

Also have you ever tried to rebound your estrogen with letrozole? Apparently you get 3x as much aromatase after discontinuation.

Edit: what about metformin and HCG? Metformin has been shown to help in PCOS and downregulation of aromatase. The HCG is renowned for increasing massivly estrodial by conversion in the testies.

I haven't used HCG since the early trt only days where it was readily prescribed to me Of course, they later transitioned to gonadorelin, and then enclomiphene. The clinics were always just a money grab. Unfortunately I've been unlucky in the India thread with acquiring. I'm not giving up though. Can't keep me down. Haha


I was reading much of the same material my man.

https://www.sciencedirect.com/science/article/abs/pii/S8756328216302782?utm_source=chatgpt.com

https://jcrpe.org/pdf/cf9d60d6-523c-458a-a2e6-78728d3ffbb0/articles/jcrpe.0011/JCRPE-10-377-En.pdf?utm_source=chatgpt.com

Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men

Single nucleotide polymorphism (SNP) rs2470152 of the gene CYP19A1 is associated with serum estradiol (E2) levels in Caucasian men. However, it remain…

www.sciencedirect.com

https://journals.physiology.org/doi/full/10.1152/japplphysiol.00374.2021?utm_source=chatgpt.com

https://academic.oup.com/jcem/article/106/8/e3078/6168433?utm_source=chatgpt.com

Fortunately I don't think I have the gene for simple fact I use to aromatize readily. I think it's more linked to over-exposure to Eq especially looking back at the timeframe I was running these cycles. I've never ran Eq for less than 20 weeks minimal.

And my situation is unique, but I still firmly believe in Estrogen load being relevant to Androgen load for any cycle, and that video you posted touched on all the points I've considered. It was nice to hear it from another person, and not leave me just speculating.

 

[BALLISTIC]

Dude stop using the EQ. You're just prolonging the rise in e2 and how high it will go. Add it back in after you get ultrasensitive e2 labs on test only

With a prolonged period without EQ. It's effects seem to linger for 3 months after last injection maybe even longer.

 

[xrayphoton13]

My e2 has been crashed for months. I dropped the AI thinking that would raise it, but foolishly added 150 eq to 250 test, which left it crashed. Think 9-10. I have since up'd the test to 400 and dropped the eq to 90. I will retest in. A few weeks. If that doesnt bring it up, I will add 1 mg of E/week next month.

Great thread

Dude stop using the EQ. You're just prolonging the rise in e2 and how high it will go. Add it back in after you get ultrasensitive e2 labs on test only

Also, get some dhea to fix your e2 quickly. You don't need anything illegal like dbol or ment or the methyl estradiol they 5ar that can't be measured on a lab test

Thread 'Low Estradiol? Here's How DHEA Can Fix Your "Crashed" E2'

Sep 21, 2025

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Read Now on typeiix.substack.com​

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Summary​

Estradiol (E2) serves essential physiological functions in men beyond its recognized role in female reproductive biology. When circulating E2 concentrations fall below normal ranges—often in the context of anabolic-androgenic steroid use—the resulting syndrome manifests primarily as joint pain (arthralgia), alongside metabolic, cognitive, and sexual dysfunction.
DHEA (dehydroepiandrosterone) functions as both a direct estrogen receptor ligand and a precursor to estradiol biosynthesis...

• Type-IIx
• crashed e2 dhea estradiol estrogen
• Replies: 45
• Forum: Steroid Forum

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