Aromatase Inhibitors Fix the Number but Break the System, open discussion.

This is something I've been wondering about, why no short esters?
From pharma, it's easy to purchase e2V and e2C amps/vials.

The follow raws are all insanely easy to get
e2base
e2cyp
e2e
e2v
e2undec

There's e2ace, seemly not popular and difficult to get, used in some non-inj pharma products.

Then there's e2b which apparently, is cheap and very easy to get.

It was the first estrogen to be used in humans.
No longer popular now, but still available for pets -- which means you can still buy it, pet pharma. Seems to act pretty quick if you ask me.

View attachment 376164

Raws don't cost much either.

200mg, 55bucks, from an actual legit non-UGL lab.
At 1mg/week, that's 200 weeks worth.
How i invision Photon:
1769657024201.webp
 
For males, there's a diurnal rhythm for T, which may be why some people just feel better with daily shots. Peaks in the morning, dips at night. I assumed it was the same for e2 but apparently I'm wrong.

You see here, fluctuations in T, morning v night.
Easy to mimic, using a daily short + long ester mix.
View attachment 376264

But for e2, minor variation.
View attachment 376265

Looks like boring, slow steady is probably the way to go.
So who's up for some e2 undecanoate:cool:


In some places like UK, sustanon is more commonly prescribed for TRT than Test E/C

It doesn't mimic natural circadian fluctuations exactly, but at least you get some variations (talking strictly TRT, not TRT+ or blasting)
 
In some places like UK, sustanon is more commonly prescribed for TRT than Test E/C

It doesn't mimic natural circadian fluctuations exactly, but at least you get some variations (talking strictly TRT, not TRT+ or blasting)
I like sustanon. I know some have a love hate relationship with it. But I have never had an issue with the combination esters. In my early years every blast consisted of sustanon. Even with the combination esters I've always resorted to daily dosing. I noticed I had great results.
 
I found some stuff:

"Low estrogen is also thought to be linked to abnormal lipid profile and hyperinsulinemia in men, though the mechanism is unknown."

I wonder if you could check if you've got the gene.

Also have you ever tried to rebound your estrogen with letrozole? Apparently you get 3x as much aromatase after discontinuation.

Edit: what about metformin and HCG? Metformin has been shown to help in PCOS and downregulation of aromatase. The HCG is renowned for increasing massivly estrodial by conversion in the testies.
I haven't used HCG since the early trt only days where it was readily prescribed to me Of course, they later transitioned to gonadorelin, and then enclomiphene. The clinics were always just a money grab. Unfortunately I've been unlucky in the India thread with acquiring. I'm not giving up though. Can't keep me down. Haha


I was reading much of the same material my man.






Fortunately I don't think I have the gene for simple fact I use to aromatize readily. I think it's more linked to over-exposure to Eq especially looking back at the timeframe I was running these cycles. I've never ran Eq for less than 20 weeks minimal.

And my situation is unique, but I still firmly believe in Estrogen load being relevant to Androgen load for any cycle, and that video you posted touched on all the points I've considered. It was nice to hear it from another person, and not leave me just speculating.
 
My e2 has been crashed for months. I dropped the AI thinking that would raise it, but foolishly added 150 eq to 250 test, which left it crashed. Think 9-10. I have since up'd the test to 400 and dropped the eq to 90. I will retest in. A few weeks. If that doesnt bring it up, I will add 1 mg of E/week next month.

Great thread


Dude stop using the EQ. You're just prolonging the rise in e2 and how high it will go. Add it back in after you get ultrasensitive e2 labs on test only

Also, get some dhea to fix your e2 quickly. You don't need anything illegal like dbol or ment or the methyl estradiol they 5ar that can't be measured on a lab test

 
I agree actually with almost everything you've said.

It's more just me not being able to justify the use of large quantities of the other compounds due to their lack of tolerability long term. I think that adding back E2 is kind of redundant when you could just increase the testosterone dose instead of adding other stuff on top.

Which leads to the other argument of whether testosterone has an anabolic ceiling.... I noticed that the higher I push the test, the stronger other androgens become.

I know other steroids have special effects, but the reason why they have side effects is because of these special effects....

As for the dieretic I was just going to use that telmisartan/clinlidipine/chlorthalidone combo.

There must be a reason why guys add multiple compounds instead of a fat dose of testosterone. I think @Mac11wildcat uses this approach and stays under 2 grams total androgen load.

I'm sure he has a logical explanation for it.

Anyway I hope you don't think I'm being argumentative lol
My logical explanation is side effects and covering all bases for growth. At the end of the day this entire conversation has to center on experimenting with what works for you individually. If you can maximize/achieve your goals with just test and GH I’d argue that’s the simplest and safest route. In fact I belive anyone who’s doing this casually/not for an athletic/competitive goal should minimize the complexity and get the most from the basics.

But for me, as a competitive pro, not possible.

I could run 2g of test and then have to use an insane amount of AI (I aromatize heavily) and also miss out on the unique benefits of DHTs and 19-nors.

Granted, I’m over a decade deep of finding my equation and doing this for a more intensive goal than most, but most of my experience in this realm has shown me that a cocktail at the same total dose as 1-2 drugs works far better for results, health, and minimizing the non “value added” drugs (estrogen control).

EDIT: I also believe far more in ratios than I do numbers and don’t buy into the idea that test is only useful because it aromatizes to estrogen. The low T high everything else working best is for a rare few in my experience.
 
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My logical explanation is side effects and covering all bases for growth. At the end of the day this entire conversation has to center on experimenting with what works for you individually. If you can maximize/achieve your goals with just test and GH I’d argue that’s the simplest and safest route. In fact I belive anyone who’s doing this casually/not for an athletic/competitive goal should minimize the complexity and get the most from the basics.

But for me, as a competitive pro, not possible.

I could run 2g of test and then have to use an insane amount of AI (I aromatize heavily) and also miss out on the unique benefits of DHTs and 19-nors.

Granted, I’m over a decade deep of finding my equation and doing this for a more intensive goal than most, but most of my experience in this realm has shown me that a cocktail at the same total dose as 1-2 drugs works far better for results, health, and minimizing the non “value added” drugs (estrogen control).
What is your top 2 (2) drug cocktails you’ve found to work best for you? Also curious being your size whats your IGF-1 numbers & z-score look like on your doses of GH you run?
 
My logical explanation is side effects and covering all bases for growth. At the end of the day this entire conversation has to center on experimenting with what works for you individually. If you can maximize/achieve your goals with just test and GH I’d argue that’s the simplest and safest route. In fact I belive anyone who’s doing this casually/not for an athletic/competitive goal should minimize the complexity and get the most from the basics.

But for me, as a competitive pro, not possible.

I could run 2g of test and then have to use an insane amount of AI (I aromatize heavily) and also miss out on the unique benefits of DHTs and 19-nors.

Granted, I’m over a decade deep of finding my equation and doing this for a more intensive goal than most, but most of my experience in this realm has shown me that a cocktail at the same total dose as 1-2 drugs works far better for results, health, and minimizing the non “value added” drugs (estrogen control).

EDIT: I also believe far more in ratios than I do numbers and don’t buy into the idea that test is only useful because it aromatizes to estrogen. The low T high everything else working best is for a rare few in my experience.

Mac11, appreciate you dropping in and expanding on that especially from the competitive side. Your perspective carries weight given the arena you’re operating in.

If you don’t mind, I’d be genuinely interested in digging a bit deeper into how you personally manage estrogen relative to total androgen load. Not in a “numbers for numbers’ sake” way, but practically how high you’ve pushed total androgens before E2 became something that required active mitigation, and what you noticed along the way.

Specifically at what point did estrogen shift from being “useful” to becoming more of a nuisance? What symptoms showed up first for you, water, BP, mood, lethargy, joint issues, neurological stuff? And how much of that was reflected cleanly in labs versus just felt physiologically?

I agree with you that minimal compound exposure is ideal for the majority, and that test/GH (or test/one addition) covers a lot of ground. That’s largely how I operate as well. But I also think labs alone can be misleading depending on compound choice, DHTs, 19nors, Eq, all distort the picture in different ways.

I’m especially interested in the body level feedback, joint comfort, CNS fatigue, body aches, irritability, mental sharpness. For example, nandrolone clearly improves joint comfort, but it can also quietly mask low E irritability or neurological symptoms until you step back and reassess the whole picture.

I think your point about ratios over raw numbers is a big one, and I also agree that the “test only matters because it aromatizes” argument is oversimplified at best. In my experience as well, very low test with everything else high works for a narrow subset, not the norm. It's just interesting to see more of it taking place and the results being generally positive. Clearly staying injectable E isn't responding the same as tissue level aromatization.

If you’ve got time, I think a discussion framed around how it feels at different androgen/estrogen loads rather than just chasing lab targets, would be hugely valuable for a lot of people reading.
Thanks again for sharing your insight.
 
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