Blood Pressure

Nighttime works well for me for Telmisartan and Cilnidipine. I would avoid taking a diuretic at night for the obvious reasons. I struggle to sleep as it is, the last thing I need is to be getting up to pee multiple times a night.

I take Nebivolol in the morning but I think I’m going to start taking it after I go to the gym in the morning. It’s keeping my heart rate down when I need it to increase at least some.

I take nebivolol with lunch, after gym & cardio. Candesartan in the evening.

Not sure how I came upon this regimen xD

Probably better to take both in the evening
 
It was the CilniLYV brand by Helios Pharmaceuticals. But Sampei pointed me to a source who has the Cilniheal brand so I also have some of those in route.

Thanks. Main thing for me is Aluminum on Aluminum packaging, since most meds last forever in those all metal blisters.

Still trying to track down Telmaheal LN (Telm/Cilnipidine) combo. Will let you know when someone gets back to me on it...
 
I take nebivolol with lunch, after gym & cardio. Candesartan in the evening.

Not sure how I came upon this regimen xD

Probably better to take both in the evening
I feel like Nebivolol makes me feel tired if taken before I go to the gym at 5:30AM. Plus my HR stays pretty low. It is common for my HR to get over 100 when lifting, especially on leg day. But on Nebivolol it is staying between 80-90 no matter what I’m doing. I haven’t tried cardio after taking it so that will be interesting
 
I feel like Nebivolol makes me feel tired if taken before I go to the gym at 5:30AM. Plus my HR stays pretty low. It is common for my HR to get over 100 when lifting, especially on leg day. But on Nebivolol it is staying between 80-90 no matter what I’m doing. I haven’t tried cardio after taking it so that will be interesting
Thats why i take Nebi before sleep, makes me tired and sleep much better
 
My BP usually sits around 110-117/74, both on cycle and cruise. After reading about its benefits for heart, kidney, and insulin sensitivity, I decided to try 20mg of Telmisartan.

Five days in, my BP hasn’t changed much, but I feel weaker and occasionally lightheaded. Doesn’t seem worth it, so I’m calling it quits.

Anyone else with low BP tried Telmisartan? Do the side effects fade over time, or am I just the only genius who managed to fix something that wasn’t broken?
 
My BP usually sits around 110-117 / 70-75, both on cycle and cruise. After reading about its benefits for heart, kidney, and insulin sensitivity, I decided to try 20mg of Telmisartan.

Five days in, my BP hasn’t changed much, but I feel weaker and occasionally lightheaded. Doesn’t seem worth it, so I’m calling it quits.

Anyone else with low BP tried Telmisartan? Do the side effects fade over time, or am I just the only genius who managed to fix something that wasn’t broken?
I don’t think I’d use a BP medication if my BP was optimal like yours. You can always cut the pill in half and try 10mg but I don’t see the point.
 
My BP usually sits around 110-117/74, both on cycle and cruise. After reading about its benefits for heart, kidney, and insulin sensitivity, I decided to try 20mg of Telmisartan.

Five days in, my BP hasn’t changed much, but I feel weaker and occasionally lightheaded. Doesn’t seem worth it, so I’m calling it quits.

Anyone else with low BP tried Telmisartan? Do the side effects fade over time, or am I just the only genius who managed to fix something that wasn’t broken?

The benefits of Telm that go beyond BP are really only significant at the highest dose, 80mg.

While you don't need a BP med, the answer to your question is yes, the sides of all BP meds tend to fade with time, lightheadedness being common.

TLDR most sides are the result of certain blood vessels relaxing too much, initially. The body has an excellent rebalancing mechanism, and will make blood vessels feeding organs, like the brain, constrict back down, raising local blood pressure, and resolving side effects like dizziness.

It takes a couple of weeks to a month, but unfortunately many people who really need BP meds give up. Less than 10% of the population with high blood pressure keeps it under control with the appropriate meds, resulting in countless avoidable heart attacks, paralyzing strokes, and many other health problems like kidney failure. One fucking pill a day is all 95% need to spare themselves from that.
 
I don’t think I’d use a BP medication if my BP was optimal like yours. You can always cut the pill in half and try 10mg but I don’t see the point.
Yeah, I’m leaning the same way. No real point in messing with something that’s already in a good spot. I could try 10mg, but honestly, I don’t see the need. Probably better to just save the stash for a time when I might actually need it.

The benefits of Telm that go beyond BP are really only significant at the highest dose, 80mg.

While you don't need a BP med, the answer to your question is yes, the sides of all BP meds tend to fade with time, lightheadedness being common.

TLDR most sides are the result of certain blood vessels relaxing too much, initially. The body has an excellent rebalancing mechanism, and will make blood vessels feeding organs, like the brain, constrict back down, raising local blood pressure, and resolving side effects like dizziness.

It takes a couple of weeks to a month, but unfortunately many people who really need BP meds give up. Less than 10% of the population with high blood pressure keeps it under control with the appropriate meds, resulting in countless avoidable heart attacks, paralyzing strokes, and many other health problems like kidney failure. One fucking pill a day is all 95% need to spare themselves from that.
Appreciate the detailed breakdown. Makes total sense why the sides fade over time - seems like the body just needs a minute to recalibrate.

That said, I think I’ll sit this one out for now. No real need to push through the adjustment period when my BP is already solid. Funny enough, I’ve got a year’s worth of Telmisartan stocked up, so who knows - maybe future me will be grateful I kept it around.
 
Yeah, I’m leaning the same way. No real point in messing with something that’s already in a good spot. I could try 10mg, but honestly, I don’t see the need. Probably better to just save the stash for a time when I might actually need it.


Appreciate the detailed breakdown. Makes total sense why the sides fade over time - seems like the body just needs a minute to recalibrate.

That said, I think I’ll sit this one out for now. No real need to push through the adjustment period when my BP is already solid. Funny enough, I’ve got a year’s worth of Telmisartan stocked up, so who knows - maybe future me will be grateful I kept it around.

FYI unlike the vast majority of meds that can last for decades beyond their expiration. Telm is uniquely susceptible to degradation from humidity. So sensitive I've seen a quiz for pharmacists that includes a question about what they should tell the elderly customer about her list of meds and the weekly pill organizer she was going to start using.

The answer? Don't put Telm in the organizer, leave it in its original packaging. It can degrade that fast.

India pharma is best for this, since they use those awesome aluminum on aluminum blister packs.
 
FYI unlike the vast majority of meds that can last for decades beyond their expiration. Telm is uniquely susceptible to degradation from humidity. So sensitive I've seen a quiz for pharmacists that includes a question about what they should tell the elderly customer about her list of meds and the weekly pill organizer she was going to start using.

The answer? Don't put Telm in the organizer, leave it in its original packaging. It can degrade that fast.

India pharma is best for this, since they use those awesome aluminum on aluminum blister packs.
My prescription telmisartan comes in bottles with only 30 pills and a dehumidifier item (desiccant capsule) inside the bottle.
 
My prescription telmisartan comes in bottles with only 30 pills and a dehumidifier item (desiccant capsule) inside the bottle.

Mine as well. The pharmacist filled 90 with 3 x 30 bottles and explained they were giving them like, rather than one bottle of 90 because they're not supposed to unseal the bottles.

I had it filled elsewhere once, and they did just dump them all into one. So not all pharmacists are equal apparently.

It's the one pill I leave in its Aluminum/Aluminum blister pack rather than load into my organizer,

I've seen an experiment where Telm in a regular prescription bottle, stored in a bathroom, lost 50% of its efficacy by the 90th tablet,
 
I guess I should have added that they are sealed in addition to having a twist off cap. So you are opening only 30 pills at a time and there is desiccant in there for those pills.
 
I guess I should have added that they are sealed in addition to having a twist off cap. So you are opening only 30 pills at a time and there is desiccant in there for those pills.

Yeah same with mine. It's as good as it gets with US generic packaging. Limited to 30 tabs being exposed, desiccant in bottle. I'm obsessed with keeping BP perfectly controlled, so I still prefer the blister packs from India pharma.

The only reason I filled the telm tabs prescription locally is because we're still waiting for combo Telm/Cildipidine tabs from PCT24 to become available. I had been using Telm/Amlodipine combo tablets which were awesome, but Cildipidine is a major upgrade from Amlodipine in terms of far lower edema risk and additional health benefits it's worth the hassle of taking them seperately.

This is an ad, but it does sum up some of Cildipidine's advantages. It protects the kidneys and improves liver function via a second channel of calcium blocking no other drug in this class has. Insane it's not available in the US.

 
FYI unlike the vast majority of meds that can last for decades beyond their expiration. Telm is uniquely susceptible to degradation from humidity. So sensitive I've seen a quiz for pharmacists that includes a question about what they should tell the elderly customer about her list of meds and the weekly pill organizer she was going to start using.

The answer? Don't put Telm in the organizer, leave it in its original packaging. It can degrade that fast.

India pharma is best for this, since they use those awesome aluminum on aluminum blister packs.
Damn I had no idea it did that. I keep them in an organizer AND in the bathroom with our shower. It gets super humid in there. BP is still good though so far... ::knocks on wood::
 
Amlodipine caused massive swelling of ankles - feet, as I have described here before.

I am taking prescribed Telmisartan and metoprolol. I chose the telmisartan and talked about it with my doc and doc agreed. When that did not sufficiently control blood pressure, doc added metoprolol.

It does better, but I am still not down at 120/70 or below.

They do not seem to affect my workouts, however, which is important to me.

I do not tolerate diuretics well. Lots of cramping, which interferes with my ability to workout. When I started diuretics, I was doing squats and I was seeing stars. Huge cramping. Doc said it was in my head (different doc) since nobody else was reporting that and this was frontline prescription to address . . . blah, blah, blah. I was like, "Doc, do any of your other patients taking this pick up a heavy weight and move it until they cannot physically move it anymore, rest a couple of minutes, and do so again, while muscles are burning and in pain, pushing through it? Doc just stared at me and blinked.

So what are your thoughts on adding Cilnidipine for a little further blood pressure control, keeping in mind that I did not tolerate Amlodipine at all. As I wrote here before, huge jiggly blobs on top of my feet, lol.

I am having trouble locating literature on the web on such a combination as an angiotensin II receptor blocker, a beta blocker, and a dihydropyridine calcium channel blocker.

AI says clinidipine not approved in the US for humanoids.
 
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PS - I do regular cardio, too. I get the heart rate at least into 140s, sometimes into 150s, for a sustained period. I used to go 160s, but all those age related danger zone cardio charts in the gym got me a little freaked out when I viewed them and saw that this was not recommended for my age, or was danger all red for emphasis, lol.
 
Amlodipine caused massive swelling of ankles - feet, as I have described here before.

I am no Telmisartan and metoprolol. I chose the telmisartan and talked about it with my doc and doc agreed. When that did not sufficiently control blood pressure, doc added metoprolol.

It does better, but I am still not down at 120/70 or below.

They do not seem to affect my workouts, however, which is important to me.

I do not tolerate diuretics well. Lots of cramping, which interferes with my ability to workout. When I started diuretics, I was doing squats and I was seeing stars. Huge cramping. Doc said it was in my head (different doc) since nobody else was reporting that and this was frontline prescription to address . . . blah, blah, blah. I was like, "Doc, do any of your other patients taking this pick up a heavy weight and move it until they cannot physically move it anymore, rest a couple of minutes, and do so again, while muscles are burning and in pain, pushing through it? Doc just stared at me and blinked.

So what are your thoughts on adding Cilnidipine for a little further blood pressure control, keeping in mind that I did not tolerate Amlodipine at all. As I wrote here before, huge jiggly blobs on top of my feet, lol.

I strongly recommend you try it.

In the countries it's available, it's very often used to replace Amlodipine in patients who can't tolerate it due to edema. Off the top of my head it worked as well as Amlodipine for BP control, without the edema side effect in over 90% of people who had edema with Amlodipine, Then you consider the other health benefits from opening micro vessels in the kidney and liver, and it's a no brainer.

Keep in mind you need 2x the dose of Cild to get the equivalent BP reduction effect of Amlodipine.

If you're adding it to your current combo, I'd start with 5mg (=2.5mg Amlodipine). If after a couple of weeks all is well, and you want to lower BP further try 10mg.

PCT24 has Cildipidine

5mg 1x10 60¢
10mg 1x10 80¢
20mg 1x10 $1

They're splittable, so I'd get the 10s. That will allow you to try 5mg, but I think it's likely you'll end up using 10mg.
 
A low reading recently was 133/73, but if I skip cardio for a couple of weeks when work gets really busy, the systolic creeps up into the 80s and sometimes even the 90s. Diastolic goes to high 130s to low 140s. Occasionally higher. Not good numbers for being on two blood pressure medications.
 
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