Bolus: The only GH book you'll ever need is NOW SHIPPING worldwide

[serkan]

I would buy the book for anti-aging purposes. Can anyone recommend it?

 

[AlexDavis43]

I would buy the book for anti-aging purposes. Can anyone recommend it?

So far, people are just saying it arrived in the mail. Don't think anyone here has read it yet.

 

[readalot]

I would buy the book for anti-aging purposes. Can anyone recommend it?

You use GH for shredded gainz and maybe some healthspan improvement at the expense of lifespan.

GH and "anti aging" don't mix.

Growth Hormone and Aging: Updated Review - PMC

Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of neuroendocrine aging, as one of causes of ...

pmc.ncbi.nlm.nih.gov

 

[bigMoJo]

You use GH for shredded gainz and maybe some healthspan improvement at the expense of lifespan.

GH and "anti aging" don't mix.

Growth Hormone and Aging: Updated Review - PMC

Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of neuroendocrine aging, as one of causes of ...

pmc.ncbi.nlm.nih.gov

Good point, but the shortened lifespan from endotoxins will likely be more pernicious than hGH. May as well get the "gainz."

 

[Type-IIx]

Good point, but the shortened lifespan from endotoxins will likely be more pernicious than hGH. May as well get the "gainz."

If Readalot’s had any good points he wouldn’t have to post 18 h a day here and across all the other forums hoping he gets a like. I can’t speak to what he actually wrote without previewing the ignored comment — something I have a policy against.

I would buy the book for anti-aging purposes. Can anyone recommend it?

At least one guy aspired to finish it this weekend. People will chime in soon that are unbiased. I believe I addressed the topic well.

While GH/IGF-I is mitogenic meaning that it increases cell division and so therefore, an aspect of the aging process, in other respects, aspects of the aging process mimic GH deficiency, in line with the diminution to GH/IGF-I that is age related, and are partly reversible by GH repletion.

Otherwise I wouldn’t have devoted whole sections to it.

 

[bigtom343]

You use GH for shredded gainz and maybe some healthspan improvement at the expense of lifespan.

GH and "anti aging" don't mix.

Growth Hormone and Aging: Updated Review - PMC

Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of neuroendocrine aging, as one of causes of ...

pmc.ncbi.nlm.nih.gov

Not a bad scientific review. The part about how taller people go downhill faster than shorter people is good knowledge to have. The review was somewhat biased towards the theory that HGH isn’t “anti-aging.” It would have been beneficial to see studies of HGH effects on the population of a 55 and up community, such as The Villages in Florida’s.

 

[Type-IIx]

From HGH vs IGF-1

Fair point actually (I was going to breeze past this post at first). I've remarked about the long-term data on this population before; and when I did so I was careful to point out that since lifespan would be significantly reduced for this population without GH/IGF-I replacement, it's difficult to draw associations about qualitatively different uses in our population.

However, this data does not stand alone; it is supported by in vitro data that fails to show any causal effect of GH/IGF-I on mutagenesis.

Long-term high dose GH/IGF-I increases body size, and epidemiological data does support an association in humans with increased body size & cancer risk, as well as morbidity. As in, very tall people tend to die younger than average, for example. A weakness with observational data like this is that it often leads to errors in associating cause/effect correctly, and misses tertiary variables and the like, or third factors that might be at play (e.g., perhaps taller people work in more dangerous professions or are placed in more risky conditions in their field of employ). This is not to say that I don't think there is some contribution of a high cell # on risk of mutagenesis over the lifespan, it seems fairly logical that larger people would be more susceptible to cancers and the like to me as a first impression.

I’ve written about the epidemiological data on GH and longevity. Almost certainly, Readalot’s learned it from my posts.

I invite anyone to search this forum for posts I’ve written for the keywords anti-aging, growth hormone, and/or epidemiological.

Epidemiological data is observational. It looks at population-wide data and attempts to draw inferences. Observational data is not controlled. There is no blindedness, no control group. It’s weak and subject to misinterpretation. Any conclusions that are drawn based on population-wide data are necessarily inferential or inductive rather than deductive.