Caffeine + Albuterol combo burns fat without diet changes

[Arnold Strong]

Abstract
OBJECTIVE:
Caffeine and ephedrine was an effective combination therapy for weight loss until ephedrine was removed from the market due to safety concerns. This study investigated the combination of caffeine and albuterol as a possibly safer alternative to ephedrine.

METHODS:
In a series of experiments using cultured adipocytes, rat models, and humans, the effects of caffeine and albuterol on lipolysis, metabolic rate, food intake, and body composition were evaluated.

RESULTS:
Both caffeine and albuterol enhanced lipolysis in cultured adipocytes. Acute treatment of humans with caffeine and/or albuterol increased resting metabolic rate. Longer-term studies of rats revealed a trend for increased metabolic rate with albuterol treatment. There was increased lean mass gain concurrent with decreased fat mass gain with caffeine/albuterol treatment that was greater than albuterol treatment alone.

CONCLUSIONS:
In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses tested and change body composition without changing food intake, this combination may deserve further exploration for use in treating pediatric obesity.

http://www.ncbi.nlm.nih.gov/pubmed/26239482

 

[Docd187123]

that is a trip.

literally everybody i know who is serious about training always press me about smashing a shake immediately after training, the trainer i train with has told me to buy BCAA's to have before and during the workout, and also told me to eat a handful of skittles/or buy dextrose to mix in my shake to replenish glycogen

BCAAs are an extremely overrated supplement. If you are getting in enough protein from whole protein sources such as fish, beef, chicken, pork, whey, etc then you're getting plenty of BCAAs. Only I'm very few scenarios MIGHT they be beneficial. Bottom line is I don't waste my money on them plus if you're eating protein before you train you'll have plenty of amino acids in your system without BCAAs.

You don't need simple sugars to replenish depleted glycogen levels post workout. Simple sugars are said to spike insulin more so muscle glycogen is replenished faster but muscle glycogen is already replenished faster post workout without the need for simple sugars. Furthermore, unless you're an endurance athlete or someone with multiple training or competitive events in a single day, there is no need to rush glycogen replenishment. The insulin spike needed to do this can be had with just protein or any type of carbohydrate meal. It really boils down to this will not make any significant difference in body composition whatsoever.

he also presses me that i shouldn't train fasted that it can waste muscle.

Sure training fasted can increase the catabolic response from training but what happens afterwards is the body supercompensate a with an even in teased anabolic response at your next meal meaning train fasted if you perform better this way. Train fed or semi fasted if you perform better this way. Do whichever allows you the best performance in your training.

he actually told me the longer i take to eat/have a shake the less my muscles will recover.

Bullshit. As I mentioned earlier the increased anabolic response from training is about 24hrs not 30-60min like supplement companies or broscientists would have you beleive. Plus, most of your recovery happens during your sleep anyway.

i haven't bothered with the whole BCAA trend as i really dunno wtf to believe so i stick to whats been working for me

That just means you don't feel like making charitable contributions to the supplement companies. I wouldn't waste my money either.

 

[ChuckSipes]

BCAAs are an extremely overrated supplement. If you are getting in enough protein from whole protein sources such as fish, beef, chicken, pork, whey, etc then you're getting plenty of BCAAs. Only I'm very few scenarios MIGHT they be beneficial. Bottom line is I don't waste my money on them plus if you're eating protein before you train you'll have plenty of amino acids in your system without BCAAs.

You don't need simple sugars to replenish depleted glycogen levels post workout. Simple sugars are said to spike insulin more so muscle glycogen is replenished faster but muscle glycogen is already replenished faster post workout without the need for simple sugars. Furthermore, unless you're an endurance athlete or someone with multiple training or competitive events in a single day, there is no need to rush glycogen replenishment. The insulin spike needed to do this can be had with just protein or any type of carbohydrate meal. It really boils down to this will not make any significant difference in body composition whatsoever.



Sure training fasted can increase the catabolic response from training but what happens afterwards is the body supercompensate a with an even in teased anabolic response at your next meal meaning train fasted if you perform better this way. Train fed or semi fasted if you perform better this way. Do whichever allows you the best performance in your training.



Bullshit. As I mentioned earlier the increased anabolic response from training is about 24hrs not 30-60min like supplement companies or broscientists would have you beleive. Plus, most of your recovery happens during your sleep anyway.



That just means you don't feel like making charitable contributions to the supplement companies. I wouldn't waste my money either.

dude i really do appreciate the time you put in here.

 

[ergomaniac]

since this study has been posted a couple of times...
and maybe its just me but I find it incredible that researchers could even detect an actual increase in body fat of 4g. being that there is about 28g to an ounce and 16 of those in a pound.
if we do take those figures literally then 500g of carbs increases fat deposits. more so in obese subjects.
what would happen if some protein was added, and my tdee was less than that. being as how Im more likely to get struck by lightning than have protein turn into fat, I should be safe, right.
after all "results demonstrate that de novo lipid synthesis from an unusually large carbohydrate load is not greater in obese than in lean individuals".
but I guess it happens.
and a fat free diet is practically impossible.

so I guess ill have to look to the experts to answer my concerns here. I found this by googling de novo lipogenesis.
http://bodyrecomposition.com/fat-loss/how-we-get-fat.html
heres the gist of it.

1. carbs are rarely converted to fat and stored as such.
2. when you eat more carbs you burn more carbs and less fat, eat less carbs and you burn less carbs and more fat.
3. protein is basically never going to be converted to fat and stored as such.
4. when you eat more protein you burn more protein (and by extension less carbs and fat); eat less protein and you burn less protein (and by extension more carbs and more fat)
5. ingested dietary fat is primarily stored, eating more of it doesn't impact on fat oxidation to a significant degree.

1. excess dietary fat is stored as fat.
2. excess dietary carbs increases carb oxidation, impairing fat oxidation; more of your daily fat intake is stored as fat.
3. excess dietary protein increases protein oxidation, impairing fat oxidation; more of your daily fat intake is stored as fat.

which leaves me with more questions then answers. im not sure how this study was introduced here, or what its implications were, but basically it seems that eating too many carbs will result in fat gain, de novo or not. and that's not the end of the story...
im going to bury my head in some textbooks, studies, websites, etc to find some real answers.

 

[Docd187123]

so I guess ill have to look to the experts to answer my concerns here. I found this by googling de novo lipogenesis.
http://bodyrecomposition.com/fat-loss/how-we-get-fat.html
heres the gist of it.

1. carbs are rarely converted to fat and stored as such.
2. when you eat more carbs you burn more carbs and less fat, eat less carbs and you burn less carbs and more fat.
3. protein is basically never going to be converted to fat and stored as such.
4. when you eat more protein you burn more protein (and by extension less carbs and fat); eat less protein and you burn less protein (and by extension more carbs and more fat)
5. ingested dietary fat is primarily stored, eating more of it doesn't impact on fat oxidation to a significant degree.

1. excess dietary fat is stored as fat.
2. excess dietary carbs increases carb oxidation, impairing fat oxidation; more of your daily fat intake is stored as fat.
3. excess dietary protein increases protein oxidation, impairing fat oxidation; more of your daily fat intake is stored as fat.

which leaves me with more questions then answers. im not sure how this study was introduced here, or what its implications were, but basically it seems that eating too many carbs will result in fat gain, de novo or not. and that's not the end of the story...
im going to bury my head in some textbooks, studies, websites, etc to find some real answers.

That's from Lyle's site. Lyle also posted the study you're talking about, the one I linked, on his forum to answer someone's question.

Sworder mistakenly stated that eating too many carbs, especially towards bedtime, will cause the body to convert them to fat. I addressed that statement with the study. You're right, excess carbs can lead to fat gains if the total calories are too high but that's not what I was arguing against which was specifically that carbs do NOT turn into or get stored as fat on a clinically significant level as evidenced by that study among others.

 

[ergomaniac]

That's from Lyle's site. Lyle also posted the study you're talking about, the one I linked, on his forum to answer someone's question.

Sworder mistakenly stated that eating too many carbs, especially towards bedtime, will cause the body to convert them to fat. I addressed that statement with the study. You're right, excess carbs can lead to fat gains if the total calories are too high but that's not what I was arguing against which was specifically that carbs do NOT turn into or get stored as fat on a clinically significant level as evidenced by that study among others.

in other words, the fact that its bedtime, doesn't magically turn carbs into fat. agreed.

that's the first time ive been on lyles site, believe it or not. ill have to go through it a bit.

still working on the tabouleh recipe btw. I bought 5 of them this week .

 

[Docd187123]

in other words, the fact that its bedtime, doesn't magically turn carbs into fat. agreed.

that's the first time ive been on lyles site, believe it or not. ill have to go through it a bit.

still working on the tabouleh recipe btw. I bought 5 of them this week .

I've read most of the articles on his site. Lots of good info. You'll definitely enjoy reading through it.

Keep at it. If you need more help I'm always here. Maybe I'll make a video and YouTube it lol. I'll link you it hahaha