Caffeine + Albuterol combo burns fat without diet changes

[Arnold Strong]

Abstract
OBJECTIVE:
Caffeine and ephedrine was an effective combination therapy for weight loss until ephedrine was removed from the market due to safety concerns. This study investigated the combination of caffeine and albuterol as a possibly safer alternative to ephedrine.

METHODS:
In a series of experiments using cultured adipocytes, rat models, and humans, the effects of caffeine and albuterol on lipolysis, metabolic rate, food intake, and body composition were evaluated.

RESULTS:
Both caffeine and albuterol enhanced lipolysis in cultured adipocytes. Acute treatment of humans with caffeine and/or albuterol increased resting metabolic rate. Longer-term studies of rats revealed a trend for increased metabolic rate with albuterol treatment. There was increased lean mass gain concurrent with decreased fat mass gain with caffeine/albuterol treatment that was greater than albuterol treatment alone.

CONCLUSIONS:
In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses tested and change body composition without changing food intake, this combination may deserve further exploration for use in treating pediatric obesity.

http://www.ncbi.nlm.nih.gov/pubmed/26239482

 

[Docd187123]

Lol, according to you macros are not converted to calories.

They're not. They have a calorie amount alloted to them but hey are converted into, once again, amino acids, FFA, glucose, etc.

My analogy again, in the gain hope that the third time is the charm..... Ladders are feet, a tape measure gets converted to inches, a thermometer is degrees C or F, a triple beam balance is grams....

 

[swolteam6]

If only I was a rat

I literally busted out laughing out loud

 

[Sworder]

They're not. They have a calorie amount alloted to them but hey are converted into, once again, amino acids, FFA, glucose, etc.

My analogy again, in the gain hope that the third time is the charm..... Ladders are feet, a tape measure gets converted to inches, a thermometer is degrees C or F, a triple beam balance is grams....

And glucose, amino acids and FFA are converted into?.... Calories!!

 

[Docd187123]

And glucose, amino acids and FFA are converted into?.... Calories!!

Glucose is used as energy or converted to glycogen.

FFA get stored as fat

Amino acids either get stored in muscle or converted to glucose and used as energy.

It's not that difficult. Breathe....

 

[Sworder]

Glucose is used as energy or converted to glycogen.

FFA get stored as fat

Amino acids either get stored in muscle or converted to glucose and used as energy.

It's not that difficult. Breathe....

So all FFA are stored as fat? LMAO this is getting better.

 

[Docd187123]

So all FFA are stored as fat? LMAO this is getting better.

Dietary fat gets stored as fat. You're not in much of a position to laugh since apparently you don't understand the back of a fruit loops box but so be it

 

[CensoredBoardsSuck]

Glucose is used as energy or converted to glycogen.

FFA get stored as fat

Amino acids either get stored in muscle or converted to glucose and used as energy.

It's not that difficult. Breathe....

 

[Docd187123]

Have you ever had a conversation with a brick wall? I did once when I was extremely drunk borderline alcohol poisoning. This reminds me of talking to that brick wall.....

 

[Sworder]

Dietary fat gets stored as fat. You're not in much of a position to laugh since apparently you don't understand the back of a fruit loops box but so be it

Lol.. I am done in this thread. Let's derail another one later.

 

[Sworder]

Have you ever had a conversation with a brick wall? I did once when I was extremely drunk borderline alcohol poisoning. This reminds me of talking to that brick wall.....

One of my Ex roommates talked to a light post and thought she was talking to God through it. She jumped in front of a car after to repent for her sins. She is okay now

 

[ergomaniac]

There is nothing true in this statement sorry. It couldn't be further from the truth.



It has nothing to do with me working out but the fact I tailor my intake to my stats and goals. It just so happens that I finish training usually around 10pm so I eat a shit ton when I get home.



It has to do with the macronutrients not the calories or amount of food.



Again, this is incorrect. You're severely overestimating the power of insulin. You think being hypocaloric but drinking 900cals of juice at bedtime will cause fat? There's more to it than that and the answer is highly unlikely as DNL is grossly overstated in the BB world. The idea humans turn carbs to fat is based on rat models mainly but rats process carbs very differently than humans do. DNL is a rare process in humans and for it to be an issue you would need somewhere along the lines of 700-900g of carbs a day for several days straight.

Here is but one study

Am J Clin Nutr. 1987 Jan;45(1):78-85. Links
Carbohydrate metabolism and de novo lipogenesis in human obesity.

Acheson KJ, Schutz Y, Bessard T, Flatt JP, Jéquier E.
Respiratory exchange was measured during 14 consecutive hours in six lean and six obese individuals after ingestion of 500 g of dextrin maltose to investigate and compare their capacity for net de novo lipogenesis. After ingestion of the carbohydrate load, metabolic rates rose similarly in both groups but fell earlier and more rapidly in the obese. RQs also rose rapidly and remained in the range of 0.95 to 1.00 for approximately 8 h in both groups. During this time, RQ exceeded 1.00 for only short periods of time with the result that 4 +/- 1 g and 5 +/- 3 g (NS) of fat were synthesized via de novo lipogenesis in excess of concomitant fat oxidation in the lean and obese subjects, respectively. Results demonstrate that net de novo lipid synthesis from an unusually large carbohydrate load is not greater in obese than in lean individuals.


^^^^ that's 2000calories of sugar, 500g, and the amount of fat synthesized through DNL was about 4g or a whopping 36calories worth of fat.



I agree with this last part

since this study has been posted a couple of times...
and maybe its just me but I find it incredible that researchers could even detect an actual increase in body fat of 4g. being that there is about 28g to an ounce and 16 of those in a pound.
if we do take those figures literally then 500g of carbs increases fat deposits. more so in obese subjects.
what would happen if some protein was added, and my tdee was less than that. being as how Im more likely to get struck by lightning than have protein turn into fat, I should be safe, right.
after all "results demonstrate that de novo lipid synthesis from an unusually large carbohydrate load is not greater in obese than in lean individuals".
but I guess it happens.
and a fat free diet is practically impossible.

 

[romaleos]

Dietary fat gets stored as fat. You're not in much of a position to laugh since apparently you don't understand the back of a fruit loops box but so be it

Doc may we conversate to gain respite from asinine discussion? I want to learn as well.

If my goal is fat loss, is there any difference between being in a caloric deficit either in a state of glycogenesis or ketogenesis?

 

[Docd187123]

Doc may we conversate to gain respite from asinine discussion? I want to learn as well.

If my goal is fat loss, is there any difference between being in a caloric deficit either in a state of glycogenesis or ketogenesis?

You can PM me anytime Romaleos.

 

[ChuckSipes]

@Docd187123 props for your patience. I've almost cut my face off a few times in this thread.


one thing I've been wondering is the timing important of a post work out meal/shake?

 

[Docd187123]

@Docd187123 props for your patience. I've almost cut my face off a few times in this thread.


one thing I've been wondering is the timing important of a post work out meal/shake?

How important a post workout shake is to you will depend on a few things.

1) do you meet your daily calorie and macro needs which are tailored to your goals? If so, this is the most important aspect of nutrition.

2) do you meet your daily calorie and macro needs which are tailored to your goals? If so, this is the second most important aspect of nutrition lol.

3) do you eat a pre workout meal an hour or two before the gym? If so, the importance of post workout nutrition is lessened since a typical mixed meal will take 4-6hrs to digest and longer to be utilized meaning those pre workout nutrients you are are still in your system after you're done training.

4) the post workout "window" is more like a garage door. Supplement companies would have you beleive you need to get nutrients and protein in as soon as possible so they market you whey which is a fast digesting protein. Next they marketed hydrolyzed protein which is faster, barely, but it was the next big thing. The in erased anabolic response from training will last around 24hrs so instead of a 30-60min window you really have the rest of the day and into the next day to reap the benefits of post workout nutrition.

5) is it convenient? I usually will bring a shake with me or eat a meal not long after the gym bc it's both convenient and I'm hungry. If I miss this meal or shake due to convenience I don't worry about it at all. I'll still get my macros in later in the day and as mentioned earlier, that's the number 1 fsctor.

 

[Sworder]

5) is it convenient? I usually will bring a shake with me or eat a meal not long after the gym bc it's both convenient and I'm hungry. If I miss this meal or shake due to convenience I don't worry about it at all. I'll still get my macros in later in the day and as mentioned earlier, that's the number 1 fsctor.

Good post! Many don't know about the "window" being larger than presumed, also the protein companies bullshit that they use to try to make a sale.
Now if you could only spell factor without a S....
Good fucking morning.

 

[CensoredBoardsSuck]

Good post! Many don't know about the "window" being larger than presumed, also the protein companies bullshit that they use to try to make a sale.
Now if you could only spell factor without a S....
Good fucking morning.

And if you only knew the difference between plural and possessive nouns...

Also, your posts would make more sense if you knew when to end a sentence and start a new one.

 

[Sworder]

And if you only knew the difference between plural and possessive nouns...

Also, your posts would make more sense if you knew when to end a sentence and start a new one.

No CBS, I am not having it from you today! No! No! No!

 

[ChuckSipes]

How important a post workout shake is to you will depend on a few things.

1) do you meet your daily calorie and macro needs which are tailored to your goals? If so, this is the most important aspect of nutrition.yes


2) do you meet your daily calorie and macro needs which are tailored to your goals? If so, this is the second most important aspect of nutrition lol yes

3) do you eat a pre workout meal an hour or two before the gym? If so, the importance of post workout nutrition is lessened since a typical mixed meal will take 4-6hrs to digest and longer to be utilized meaning those pre workout nutrients you are are still in your system after you're done training. i train fasted

4) the post workout "window" is more like a garage door. Supplement companies would have you beleive you need to get nutrients and protein in as soon as possible so they market you whey which is a fast digesting protein. Next they marketed hydrolyzed protein which is faster, barely, but it was the next big thing. The in erased anabolic response from training will last around 24hrs so instead of a 30-60min window you really have the rest of the day and into the next day to reap the benefits of post workout nutrition.

5) is it convenient? I usually will bring a shake with me or eat a meal not long after the gym bc it's both convenient and I'm hungry. If I miss this meal or shake due to convenience I don't worry about it at all. I'll still get my macros in later in the day and as mentioned earlier, that's the number 1 fsctor.

that is a trip.

literally everybody i know who is serious about training always press me about smashing a shake immediately after training, the trainer i train with has told me to buy BCAA's to have before and during the workout, and also told me to eat a handful of skittles/or buy dextrose to mix in my shake to replenish glycogen

he also presses me that i shouldn't train fasted that it can waste muscle.

he actually told me the longer i take to eat/have a shake the less my muscles will recover.

i haven't bothered with the whole BCAA trend as i really dunno wtf to believe so i stick to whats been working for me

 

[Sworder]

i haven't bothered with the whole BCAA trend as i really dunno wtf to believe so i stick to whats been working for me

BCAA are good to supplement depending on your diet. There are essential amino acids and non-essential. The essential cannot be made by your body and the 3 amino acids in BCAA are essential, there is 6 more too.

Your body can break down glutamine and convert it to another non-essential amino acid and vice versa.