Caffeine + Albuterol combo burns fat without diet changes

[Arnold Strong]

Abstract
OBJECTIVE:
Caffeine and ephedrine was an effective combination therapy for weight loss until ephedrine was removed from the market due to safety concerns. This study investigated the combination of caffeine and albuterol as a possibly safer alternative to ephedrine.

METHODS:
In a series of experiments using cultured adipocytes, rat models, and humans, the effects of caffeine and albuterol on lipolysis, metabolic rate, food intake, and body composition were evaluated.

RESULTS:
Both caffeine and albuterol enhanced lipolysis in cultured adipocytes. Acute treatment of humans with caffeine and/or albuterol increased resting metabolic rate. Longer-term studies of rats revealed a trend for increased metabolic rate with albuterol treatment. There was increased lean mass gain concurrent with decreased fat mass gain with caffeine/albuterol treatment that was greater than albuterol treatment alone.

CONCLUSIONS:
In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses tested and change body composition without changing food intake, this combination may deserve further exploration for use in treating pediatric obesity.

http://www.ncbi.nlm.nih.gov/pubmed/26239482

 

[MrRippedZilla]

Different subject, remember you brought it up. We are talking about people changing their lifestyle.

No, I do not agree that it evens itself out over the course of the day. That is completely wrong. Just like I do, I drink juice throughout the day. There is a large difference in how the macros/calories are used when drinking the whole gallon in the morning which is 900 calories vs drinking it throughout the day.

I gotta baby sit some other people now, don't have time for y'all right now. I don't quite know what your point is beyond the "it balances itself out throughout the day" and I do not agree with that. Timing is extremely important.

Never mind, apparently you believe caloric timing is more important than intake when it comes to fat loss.
The scientific evidence when considered as well as my experiences as a coach suggested that your very, very wrong but since you've shown yourself to be irrational and refuse to admit this (a weird habit plenty of guys have on this site) - I'll leave it at that.

 

[Docd187123]

Docd, I don't know where you find the patience to converse with this clown and still remain civil but you should be commended. Even though the information you've presented is beyond Sworder's ability to comprehend, it will still benefit others. Your example proves that even in the face of idiocy, it is still possible to remain on topic and provide beneficial information. That's not an easy thing to do. Hat's off, sir.

I don't really have the patience but i try to look at the greater good. Do I allow his inaccurate statements to stand or do I, along with RippedZilla and Dwizzle, continually correct him so the masses reading this can get a better understanding of the workings of the human body? Helping the masses generally wins but thank you

 

[Sworder]

Never mind, apparently you believe caloric timing is more important than intake when it comes to fat loss.
The scientific evidence when considered as well as my experiences as a coach suggested that your very, very wrong but since you've shown yourself to be irrational and refuse to admit this (a weird habit plenty of guys have on this site) - I'll leave it at that.

Your experience as a coach means what?
I am quoting myself, and it doesn't state "timing is more important than intake." Get some glasses soccer coach. Bold and underlined apply to you.

It's a simple numbers game. Eat 1000 calories and burn 400 and the extra 600 will be stored in your body. It's pretty simple, X amount of calories and Y time it takes to convert it to calories are the only things you need to consider.

It's not getting taken out of context. When the circlejerk is wrong they:
1. Deflect.
2. Change the subject.
3. Attack the person.

 

[Sworder]

I don't really have the patience but i try to look at the greater good. Do I allow his inaccurate statements to stand or do I, along with RippedZilla and Dwizzle, continually correct him so the masses reading this can get a better understanding of the workings of the human body? Helping the masses generally wins but thank you

Lol reading on bodybuilding.com about calories and macros will teach people a lot more than the circlejerk's posts. Docd you are better with posting as it applies to the thread but still apart of the crowd, sorry. Have a good day, Zilla CBS Docd. I am going to go play some pool.

 

[Docd187123]

Macros are calories , they are simply the food we eat ....

Bodybuilding.com : But first, what does "to macro" mean? "To macro" means tracking the number of grams of http://www.bodybuilding.com/store/protein.htm, http://www.bodybuilding.com/store/carbs.htm, and fats you consume on a particular day.

Each macronutrient yields a certain number of calories.

• One gram of protein yields 4 calories.
• One gram of carbohydrate yields 4 calories.
• One gram of fat yields 9 calories.
• One gram of alcohol yields 7 calories.

Oh okay. Just making sure I wasn't going completely insane. Thanks.

Lol @ using a bodybuilding.com article to prove your point Sworder. You who typically ask for STUDIES may I remind you accept this article not bc it's right but bc it says what you want to hear regardless of how irrelevant and incorrect it is. Ever hear of confirmation bias??? We're also talking about the same site that has articles telling us how wonderful HMB is and how ppl need more supplements lol. This has turned into a joke but hopefully ppl can see through it and weed the good info from the bad

 

[Sworder]

Lol @ using a bodybuilding.com article to prove your point Sworder. You who typically ask for STUDIES may I remind you accept this article not bc it's right but bc it says what you want to hear regardless of how irrelevant and incorrect it is. Ever hear of confirmation bias??? We're also talking about the same site that has articles telling us how wonderful HMB is and how ppl need more supplements lol. This has turned into a joke but hopefully ppl can see through it and weed the good info from the bad

it's basic common knowledge about how macros and calories work. Read the back of your fruit loops on nutrition info.

 

[Docd187123]

Different subject, remember you brought it up. We are talking about people changing their lifestyle.

No, I do not agree that it evens itself out over the course of the day. That is completely wrong. Just like I do, I drink juice throughout the day. There is a large difference in how the macros/calories are used when drinking the whole gallon in the morning which is 900 calories vs drinking it throughout the day.

I gotta baby sit some other people now, don't have time for y'all right now. I don't quite know what your point is beyond the "it balances itself out throughout the day" and I do not agree with that. Timing is extremely important.

What you agree with is irrelevant outside the context of your own fantasy world where food you eat before bed magically turns to fat like a unicorn riding the rainbow to the pot of gold. When you're ready to have an open minded conversation on the topic, I'm sure Rippedzilla will be more than happy to educate you. Heck even I'll be willing to just to show CBS how deep my patience runs.

 

[Docd187123]

it's basic common knowledge about how macros and calories work. Read the back of your fruit loops on nutrition info.

Apparently you don't even understand the back of the fruit loops box yourself lol. Calories are a unit of measure. That's like saying does your ladder turn into inches bc it's a 20ft ladder? No it's still a fucking ladder....

 

[Sworder]

Macros don't get broken down to calories. Protein gets turned to amino acids for example and carbs turn to glucose.

Look closely how the macros actually ARE turned into calories. It states and breaks it down very easily for you.

 

[Docd187123]

Furthermore, you have yet to anywhere near remotely address the two studies I've posted in here:

1) study participants, both lean and obese ppl, were given 500g or 2000calories of PURE SUGAR and only a whopping 4g of fat was synthesized which equates to an amazing 36calories of fat. Wowwwwwwwwww, OMG, look at all the fat gains those ppl had......

2) study participants were given the majority of their carbohydrate intake later at night near bedtime vs control. measured parameters including fat loss, abdominal circumference, etc were better in the group that are their carbs at night.....

 

[Docd187123]

Look closely how the macros actually ARE turned into calories. It states and breaks it down very easily for you.

That says nothing of macros being broken down into calories. That says how many calories are associated to each macro. Reading comprehension isnt your strong suit is it?

 

[CensoredBoardsSuck]

I am going to go play some pool.

 

[Sworder]

Lol @ using a bodybuilding.com article to prove your point Sworder. You who typically ask for STUDIES may I remind you accept this article not bc it's right but bc it says what you want to hear regardless of how irrelevant and incorrect it is. Ever hear of confirmation bias??? We're also talking about the same site that has articles telling us how wonderful HMB is and how ppl need more supplements lol. This has turned into a joke but hopefully ppl can see through it and weed the good info from the bad

It's basic diet information that is well known to everybody. It's like stating testosterone is an anabolic steroid and having to prove it with a study lol it's common sense.

 

[Docd187123]

It's basic diet information that is well known to everybody. It's like stating testosterone is an anabolic steroid and having to prove it with a study lol it's common sense.

Then why do you still not get it?

 

[Sworder]

Then why do you still not get it?

You are the one that doesn't understand that macros and everything you eat turns into calories.

G'morning

 

[Docd187123]

You are the one that doesn't understand that macros and everything you eat turns into calories.

G'morning

Good morning. This is becoming a joke. They don't turn to calories. They turn into amino acids or glucose for protein, glucose for carbs, free fatty acids for fats, etc. Stop trying to save face and start trying to learn.

 

[Wiltedrose]

View attachment 28134
Abstract
OBJECTIVE:
Caffeine and ephedrine was an effective combination therapy for weight loss until ephedrine was removed from the market due to safety concerns. This study investigated the combination of caffeine and albuterol as a possibly safer alternative to ephedrine.

METHODS:
In a series of experiments using cultured adipocytes, rat models, and humans, the effects of caffeine and albuterol on lipolysis, metabolic rate, food intake, and body composition were evaluated.

RESULTS:
Both caffeine and albuterol enhanced lipolysis in cultured adipocytes. Acute treatment of humans with caffeine and/or albuterol increased resting metabolic rate. Longer-term studies of rats revealed a trend for increased metabolic rate with albuterol treatment. There was increased lean mass gain concurrent with decreased fat mass gain with caffeine/albuterol treatment that was greater than albuterol treatment alone.

CONCLUSIONS:
In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses tested and change body composition without changing food intake, this combination may deserve further exploration for use in treating pediatric obesity.

http://www.ncbi.nlm.nih.gov/pubmed/26239482

Any free-full article links? many important pieces of information are missing IMO.

What is the effective drug to weight ratio for humans (since rats are much smaller)? how was the energy expenditure measured? how was the metabolic rate determined? how long were the rats on drugs for? what were the effects after discontinuation? MoA? etc...

 

[Sworder]

Good morning. This is becoming a joke. They don't turn to calories. They turn into amino acids or glucose for protein, glucose for carbs, free fatty acids for fats, etc. Stop trying to save face and start trying to learn.

Macros don't get broken down to calories. Protein gets turned to amino acids for example and carbs turn to glucose.

I am dead-set on that.
We can continue to disagree, or agree to disagree.

I am not trying to save face. Yes, not all gets burned some gets stored, but macros are calories. And the body can use glucose as is, it can also breakdown the amino acids and create other amino acids from that.

 

[Docd187123]

I am dead-set on that.
We can continue to disagree, or agree to disagree.

I am not trying to save face. Yes, not all gets burned some gets stored, but macros are calories. And the body can use glucose as is, it can also breakdown the amino acids and create other amino acids from that.

Dead set on being wrong? Why? Ladders are feet or inches.....

 

[Sworder]

Lol, according to you macros are not converted to calories.