MESO-Rx
Anabolic Steroids
Chemman's log
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hardasnails1973
New Member
If a person has adrenal insufficency and that is not dealt with first taking TRT can make a person more suspectible to insulin imbalance. People with adrenal issues are more and likely have some degree of insulin resistance. I can spot thyroid issue a mile away with pinpoint accuracy up to >95% verified by clincal testing. I have been doing it for 5 years now..When I goto conference and seminars with MD , DO, ND. it blows them away when I
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When you.....
hardasnails1973
New Member
Identify that they may have potential thyroid issue and should get checked out due to particular signs I look for in fingers, and also eyes then muscle test to reverify it. When lab test come back they are baffled to how I knew. I have done this with adrenals as well to pinpoint imbalnace at specific time and place for adrenal issues. I had a person come in with high normal cortisol serum, but when I muscle tested which was at the same time when blood test was taken it was low. When the cortisol saliva was ran it verified in the morning it was low. At the time of blood was taken I had asked her if she was nervous or was rushed in traffic. She told me some guy cut her off on the way to the lab. I told her i suspected she had a false elevation when I found she was low.
I think you're on the right path with the insulin resistance idea but worded it backwards. T decreases insulin resistance, which is why TRT is good news for those with diabetes.
So yes, now that I have higher T levels (don't know how much higher yet), I should be more sensitive to insulin, which would explain (in part) why my blood sugar is getting low. I don't know how this happens, but I will check my endocrinology text book and get back to you all. I am hoping that as my body really adjusts to the high T, that I see a resolution to this problem. But nonetheless I will be digging deeper into things in the near future.
Hypoglycemic attacks are generally episodic and that is exactly what I am experiencing. Also, the hypoglycemia occurs when my mood is up and my joints feel better, etc., hence when my T levels are higher.
This makes me think that my fundamental problem in the first place lies in my body's energy maintenance. Caloric intake/excess drives the reproductive system. I think the weight loss did me in. But it is interesting to note that I gained all of the weight back and then some, ate multiple thousands of calories several months in a row, and only saw minor improvements in my symptoms.
NEW LABS:
Drawn at LabCorp 12 hours after my 30mg T cyp shot. I do 30mg EOD [105mg/wk.]
CBC: Normal
CMP: Normal
Total Testosterone: 963 [280-800] HIGH
SHBG: 20.2 [14.5 - 48.4]
DHT: Pending
Estradiol, sensitive: 18 [3-70]
Albumin: 4.5 [3.5-5.5]
DHEA: 291.3 [211 - 492]
Pregnenolone: Pending
TSH: 1.470 [0.450 - 4.500]
Free T4: 1.31 [0.82 - 1.77]
Free T3: 3.1 [2.0 - 4.4]
Reverse T3: 310 [90 - 350]
Vitamin B12: 610 [211-946]
Vitamin D: 38.3 [32.0 - 100.00]
IFG-1: 340 [116 - 358]
Cortisol, Urinary free
Cortisol,F, ug/L, U: 22 [reference range undefined]
Cortisol,F,uG/24hr, U: 33 [0-50]
My comments:
Man, what an improvement over 6 months ago as far as numbers go!
I feel better every week, but I still do not feel completely "normal." Maybe it will just take time to heal the physical and psychological damage that I experienced. Also, with my TT that high, my E2 is relatively low. I still have some joint cracking going on, so I wonder if I have enough E2?
The main things I need to work on now are:
Mild anxiety and low-grade depression
Libido [I can feel it coming back sometimes, but not what it used to be]
Continuing low penile sensitivity [and resulting ED]
Possible low cortisol at times
Reverse T3
Maybe raising E2
Any thoughts?
Drawn at LabCorp 12 hours after my 30mg T cyp shot. I do 30mg EOD [105mg/wk.]
CBC: Normal
CMP: Normal
Total Testosterone: 963 [280-800] HIGH
SHBG: 20.2 [14.5 - 48.4]
DHT: Pending
Estradiol, sensitive: 18 [3-70]
Albumin: 4.5 [3.5-5.5]
DHEA: 291.3 [211 - 492]
Pregnenolone: Pending
TSH: 1.470 [0.450 - 4.500]
Free T4: 1.31 [0.82 - 1.77]
Free T3: 3.1 [2.0 - 4.4]
Reverse T3: 310 [90 - 350]
Vitamin B12: 610 [211-946]
Vitamin D: 38.3 [32.0 - 100.00]
IFG-1: 340 [116 - 358]
Cortisol, Urinary free
Cortisol,F, ug/L, U: 22 [reference range undefined]
Cortisol,F,uG/24hr, U: 33 [0-50]
My comments:
Man, what an improvement over 6 months ago as far as numbers go!
I feel better every week, but I still do not feel completely "normal." Maybe it will just take time to heal the physical and psychological damage that I experienced. Also, with my TT that high, my E2 is relatively low. I still have some joint cracking going on, so I wonder if I have enough E2?
The main things I need to work on now are:
Mild anxiety and low-grade depression
Libido [I can feel it coming back sometimes, but not what it used to be]
Continuing low penile sensitivity [and resulting ED]
Possible low cortisol at times
Reverse T3
Maybe raising E2
Any thoughts?
Kwirion
New Member
In my humble opinion: SHBG is a little low normal: Normal Testosterone Levels in Men by Age - Bioavailable, Total, Free Testosterone Ranges
And DHEAs is very low - LE’s Optimal Range: 500-640 µg/dL Print Friendly
E2 too low -> 22 - 28 would be perfect - e2 works as MAOI an libido enhancer too
And DHEAs is very low - LE’s Optimal Range: 500-640 µg/dL Print Friendly
E2 too low -> 22 - 28 would be perfect - e2 works as MAOI an libido enhancer too
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I tried to read the entire thread but only made it to page 11.
The main point is that you seem to have the problem under control.
Serum concentration varies a great deal with time, peaks in 12-24 hrs then exponentially decays, so the level you measured at 12 hrs wont stay that high till the next inj. so youre probably at about the right doseage.
The main point is that you seem to have the problem under control.
Serum concentration varies a great deal with time, peaks in 12-24 hrs then exponentially decays, so the level you measured at 12 hrs wont stay that high till the next inj. so youre probably at about the right doseage.
Yea this thread is long, but looking at all of my labs, there appeared to be only one problem: low T and E. I am still up in the air about that genova saliva cortisol result, but I think the lab might be bunk. Labcorp is legit and my urinary cortisol looks spot on.
The hypoglycemia and weak shaky feelings accompanied by some anxiety is hard to pin down. It SOUNDS like a cortisol issue, but apparently not. Maybe I just need to eat more now that my Testosterone is up? Some of my issues are related to excessive exercising and weight loss. I got down to 198 lbs at 6'5" which is just unhealthy for me.
Don't sub-Q injects reach peak the fastest? So I guess it makes sense that right at 12 hours I caught that high value. Keep in mind I only inject 30mg at a time but every other day. My labs at 6 weeks of T cyp EOD and 48 hours after injecting were 560 TT and free T was top of the range [exactly], so I wonder if maybe I could do with even less than about 105mg/wk. Time for more labs?
Now I am just wondering how long it will take for me to get back to that banging 100% healthy feeling. I guess it kinda makes sense that 1 year of bad hormones can take some time to heal.
I am making some progress so let's hope it continues to set in.
I dont think you have an adrenal-cortical hormone problem now that testosterone is normalized.
Anxiety can cause a myriad of symptoms.
Your BMI is well within the normal range but if you are losing or gaining weight at more than 1lb/w that can cause problems.
Re. hypoglycemia, had fasting glucose checked ?
Yes SQ is a bit faster than IM.
You get more realistic results if you test befor a dose.
Anxiety can cause a myriad of symptoms.
Your BMI is well within the normal range but if you are losing or gaining weight at more than 1lb/w that can cause problems.
Re. hypoglycemia, had fasting glucose checked ?
Yes SQ is a bit faster than IM.
You get more realistic results if you test befor a dose.
I'm up to 225ish now. So back to a healthy weight for me.
Yea fasting glucose was normal, but I was not displaying any symptoms of hypoglycemia at that time so it makes sense.
I've been eating small meals every few hours and more calories overall the past few days and it seems to be helping. I feel better.
I never had any anxiety problems [at least nothing as remotely intense and completely maladaptive] at all before my T went low. It has gotten better on TRT, but I wonder if months of anxious thought patterns and low T take time to smooth out.
I'll do my next round of tests right before my next shot. It's weird to think that even EOD dosing provides a variation of nearly 400 points in TT. I couldn't imagine 1x/wk dosing.
I doubt it's the dosing that caused the variation, your serum levels just took longer to balance out than you thought I bet.
If you test again I would bet you are around where you are at now.
I guess we shall see! What's weird is that my urologist sent me home with a 20 week supply of injectable testosterone but no lab slip to see where my levels are. I need to call and ask about that.
virtuosa150
New Member
Your vitamin D level is in the basement as you know. Mine ws like that too. I started taking 20000iu (yep 20000) of biotics bio-d /day. My level is now 96. I've backed it off to 18000. Will retest in a few weeks. Probably will be lower now that it's fall.
Do you supplement with chromium picolinate? I had problems with reactive hypoglycemia. It's not much of a problem for me anymore I believe since I started the chromium supp.
How's your sleep?
Yea I don't tolerate oral vitamin D very well. I'll check into the chromium. I'm not even sure if my hypoglycemia is reactive.
virtuosa150
New Member
How is it that you don't tolerate oral vit D?
Do you feel sluggish after eating a lot of simple carbs, or do you feel poor when fasting? Do you have a glucose monitor?
I was like you, My E2 didn't budge form the basement until I got my T up around 900. Last tested my E2 is 29 (possibly creeping too high now) and TT943. I backed my T cyp doseage off slightly. Your problems with your joints aching will go away. Mine did at least.
Have you addressed that RT3 yet? Mine is high but since my adrenal functions are fucked, I reluctant to start.
Oral vitamin D "makes my brain feel bad." That' how I describe it. And it gives me anxiety. Sunshine does not have this effect, however.
The blood sugar issue is just strange. It doesn't have much of a relation to specific types of food. I just have to pack in the calories for days straight to make it go away. But even that could be coincidental. Still wondering about the adrenals, but my urinary cortisol looks good.
I do have a glucose monitor. It reads mid to low 70s when I feel "hypoglycemic"
And as for the joint issues, I am healing! The cracking is going away! Thank god.
RT3: I am not convinced that it is an issue. I might test it again in a few months to see if it has come down. You know how much the "treatments" for Rt3 can actually do more harm than good.
So it' been a while since I have updated this log.
I would say that I am about 60% back to normal these days.
I have been doing testosterone replacement using T cypionate 30mg on an EOD schedule for about 7.5 months now.
My last labs showed me at about 690TT, midrange free and BioT, and E2 at 23. I bumped up to 34 mg EOD two weeks ago, which works out to about 120mg/week.
Either this bump in the dosage or some other change has caused my libido to finally start coming back after an absence of nearly 2 years! Usually the age of 21-23 would be marked by a strong libido, but not for me. I can only hope it comes back all the way. I still can take me a long time to reach orgasm.
I still have some remaining issues to tackle:
Arthritis/constant injuries/tendonitis.
Mild anxiety and depression
Exacerbated morning fatigue
Fleeting hypoglycemia [Has been occurring much less frequently...to the point that I have forgotten about it at times]
Wiped out from exercise for nearly a week afterwards.
I see an endo tomorrow and hopefully we will be doing another endocrine workup to help rule out/in any other hormone abnormalities.
I would say that I am about 60% back to normal these days.
I have been doing testosterone replacement using T cypionate 30mg on an EOD schedule for about 7.5 months now.
My last labs showed me at about 690TT, midrange free and BioT, and E2 at 23. I bumped up to 34 mg EOD two weeks ago, which works out to about 120mg/week.
Either this bump in the dosage or some other change has caused my libido to finally start coming back after an absence of nearly 2 years! Usually the age of 21-23 would be marked by a strong libido, but not for me. I can only hope it comes back all the way. I still can take me a long time to reach orgasm.
I still have some remaining issues to tackle:
Arthritis/constant injuries/tendonitis.
Mild anxiety and depression
Exacerbated morning fatigue
Fleeting hypoglycemia [Has been occurring much less frequently...to the point that I have forgotten about it at times]
Wiped out from exercise for nearly a week afterwards.
I see an endo tomorrow and hopefully we will be doing another endocrine workup to help rule out/in any other hormone abnormalities.
