Defiant Pharma (US Domestic)

[The Answ3r]

I find taking the pre-workout, TNE, Sdrol, Adrol, work best 90 to 120 minutes before heavy lifting. What timing works the best for the rest of you?

When you say heavy lifting with something like TNE or Sdrol as a pre, what are we actually talking about? Real heavy compound work, 85-90% 1RM, low reps, pushing strength? Or just “feels heavy because the pre is kicking”?

Sometimes I see stacks like that and wonder if guys are preparing for a powerlifting meet… or just trying to bench press their own ego.

No shade, just genuinely curious what numbers and intensity we’re calling heavy.

 

[RockyP]

When you say heavy lifting with something like TNE or Sdrol as a pre, what are we actually talking about? Real heavy compound work, 85-90% 1RM, low reps, pushing strength? Or just “feels heavy because the pre is kicking”?

Sometimes I see stacks like that and wonder if guys are preparing for a powerlifting meet… or just trying to bench press their own ego.

No shade, just genuinely curious what numbers and intensity we’re calling heavy.

I think it’s different for each application. Powerlifters have some gnarly pre workout blends that I’ve seen (like 100 mg each of anadrol and anavar with a side of halo). Personally I just pick and choose between anadrol, anavar, and tne on back / leg / lagging bodypart days. The goal for me is optimal endurance, intensity, pumps, and anticatabolism. And it’s fun.

 

[The Answ3r]

I think it’s different for each application. Powerlifters have some gnarly pre workout blends that I’ve seen (like 100 mg each of anadrol and anavar with a side of halo). Personally I just pick and choose between anadrol, anavar, and tne on back / leg / lagging bodypart days. The goal for me is optimal endurance, intensity, pumps, and anticatabolism. And it’s fun.

That’s wild but I respect it. Everybody’s got their own mad scientist formula I guess.

In 20 years of lifting, and about 10 of that with gear, the craziest “pre” I’ve used was the old school Jack3d, some var, winny, and lately 100 mg of Armodafinil just to stay locked in and actually finish what I started. That’s been enough for heavy sets, pump days, whatever the goal is.

Maybe that’s why I’m not Mr. Olympia yet… no TNE, no Sdrol, no 100 mg Anadrol cocktails before squats. Clearly I’ve been doing it wrong this whole time.

I might experiment one day just to see what the hype is about. But lately I’ve been backing off the ego lifting anyway. Old injuries are starting to send reminder emails, and they don’t care how good the pre-workout stack is.

Appreciate you sharing though. Always interesting to see how different people approach it.

 

[Defiant Pharma]

T400 is all sold out fellas!

Have to wait on more TE raw to get here before I can make any more. It's in transit but I don't have an ETA right now.

regards,

D.

 

[RockyP]

T400 is all sold out fellas!

Have to wait on more TE raw to get here before I can make any more. It's in transit but I don't have an ETA right now.

regards,

D.

Wow that was quick. Not surprised. Great stuff.

 

[Defiant Pharma]

Wow that was quick. Not surprised. Great stuff.

Yeah, it flew off the shelves literally.

I will make some bigger batches once we secure more raws.

 

[713HTX]

Yeah, it flew off the shelves literally.

I will make some bigger batches once we secure more raws.

Please do. I plan on ordering at least 5-6!

 

[PMercy1]

I think it’s different for each application. Powerlifters have some gnarly pre workout blends that I’ve seen (like 100 mg each of anadrol and anavar with a side of halo). Personally I just pick and choose between anadrol, anavar, and tne on back / leg / lagging bodypart days. The goal for me is optimal endurance, intensity, pumps, and anticatabolism. And it’s fun.

And it’s fun.. facts bro

 

[AlexDavis43]

That’s wild but I respect it. Everybody’s got their own mad scientist formula I guess.

In 20 years of lifting, and about 10 of that with gear, the craziest “pre” I’ve used was the old school Jack3d, some var, winny, and lately 100 mg of Armodafinil just to stay locked in and actually finish what I started. That’s been enough for heavy sets, pump days, whatever the goal is.

Maybe that’s why I’m not Mr. Olympia yet… no TNE, no Sdrol, no 100 mg Anadrol cocktails before squats. Clearly I’ve been doing it wrong this whole time.

I might experiment one day just to see what the hype is about. But lately I’ve been backing off the ego lifting anyway. Old injuries are starting to send reminder emails, and they don’t care how good the pre-workout stack is.

Appreciate you sharing though. Always interesting to see how different people approach it.

squats

that's the main reason

who has been consistently going heavy on leg day for years?

answer: big mother fuckers

 

[The Answ3r]

that's the main reason

who has been consistently going heavy on leg day for years?

answer: big mother fuckers

But it’s 2026 and people are still acting like barbell back squats are the only path to Valhalla. Nah. That era had its fun.

I squatted my share back in the day. It was cool, loud, ego-boosting, everyone clapping when you unrack 5 plates. But once I dropped the straight bar and focused on hack squats, pendulum, heavy leg press, and some belt squat work, my legs actually started growing instead of my chiropractor’s income.

You can load the hell out of those movements, control the path, and keep tension where it belongs instead of surviving the lift like it’s a car crash in slow motion.

But at the end of the day, we’re all wired different. Some guys build tree trunks off back squats. Others build them off machines. We’re all just trying to grow and not limp into 40.

Lift smart, lift heavy enough, and pick your poison.

 

[ThatGuy500mg]

How are yall feeling about stack EQ and NPP? That seems like it would be a synergistic combination to me. But like it would also turn your blood to sludge and but you blood pressure at 235/159. Anyone experiment with this? I’m trying to plan out a late summer bulk to build up for a show later this year. Maybe just sticking with test/EQ and possibly kickstart it with anadrol? I’m trying to not just buy a bunch of stuff blindly that I may or may not use but still be prepared for later down the road lol

 

[The Answ3r]

How are yall feeling about stack EQ and NPP? That seems like it would be a synergistic combination to me. But like it would also turn your blood to sludge and but you blood pressure at 235/159. Anyone experiment with this? I’m trying to plan out a late summer bulk to build up for a show later this year. Maybe just sticking with test/EQ and possibly kickstart it with anadrol? I’m trying to not just buy a bunch of stuff blindly that I may or may not use but still be prepared for later down the road lol

First question, is this your first time touching EQ or NPP? If yes, don’t stack them right away. That’s how you end up not knowing which compound is doing what.

If I were you, I’d start simple: Test + EQ first. Something like 500/400. Run that, pull bloods, and see what actually happens.

Two big things to watch with EQ:
1. E2 suppression (for some guys it tanks it).
2. HCT creeping up.

Those are the two common headaches. If your e2 crashes or your hct starts climbing, you’ll know EQ is the variable, not some mystery synergy.

Stacking EQ + NPP right away isn’t “synergy,” it’s more like introducing two variables that both affect RBC, blood pressure, recovery, and hormones in different ways. NPP brings prolactin and potential mental sides. EQ brings RBC and possible e2 suppression. Combine both and now you’re playing hormone roulette.

That said, solid combinations long term:
1. Test/EQ/Mast.
2. Test/NPP/Mast.

Both work very well, but once you already know how you respond individually.

As for show prep bulk, the smartest move isn’t buying everything just to have it. It’s building a solid base, watching bloodwork, then adjusting intentionally.

Anadrol as a kickstart can work, sure. But I’d still see how you respond to the core stack first before piling more stress on top.

Keep it simple. Let bloods guide you. Add complexity only when you actually need it.