Here’s the formula I use from PhloJel for making Testosterone Cream 20% strength. It’s really super simple, and I’ve been using QSC’s test base for this. Please note that this cream is much stronger and way more bioavailable than various transdermals such as Androgel, and some of the other creams and gels available from various pharmacies.
Equipment Needed:
Slab & Spatula, (optional two 100mlL syringes with syringe adapter)
Procedure to make 50g
This will fill up two Topi-Click 35 dispensers that dispense 0.25mL per click using PhloJel Ultra as the base penetrant which can be found at this link
https://phlojelultra.us
Triturate and levigate 10g testosterone base with 13mL (11g) Olive Oil until non-gritty. Make sure to do this step well so that it’s truly non gritty. Watch the videos linked below for these principles being demonstrated.
Incorporate 40g PhloJel Ultra in divided portions until complete. The olive oil is considered a pharmaceutical necessity and is not included in the total weight. You can optionally incorporate up to, but no more than 1mL of DSMO, but I prefer to use it separately (if it at all) with a small spray mist bottle if I want faster absorption. I generally don’t use any DMSO, but it is an option.
The final product should be soft, yet firm and non-gritty.
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I’d recommend a starting dose of 1mL per day either in divided doses or a single dose in the morning for TRT based on using the PhloJel Ultra as the base penetrant, and adjust your dose up or down from there. Scrotal application will give you higher levels. You’ll need to shave often to get the best results and it’s really super simple and quick to do with a five bladed Gillette swivel head razor as Doctor Keith Nichols talks about in one of his videos below, along with transference risks, etc. I believe T levels peak in just a few hours with this cream and it only takes something like three days to achieve a steady state, so it’s much quicker than with injections such a test cypionate. You could also use this cream as a booster along with injections.
Here’s a few videos demonstrating the principles of geometric delusion and levigation for compounding will come in handy if you decide to make this.
View: https://youtu.be/we8gV8DQWMc?si=Hp90WkycAr6DxZ2J
View: https://youtu.be/hualGfSQPqg?si=4biJr6qjucJhwb0P
View: https://youtu.be/2oihtO3xsSE?si=e-b5iM5J9oohEB3I
I used the PhloJel Ultra base to make my cream because its been proven to work great, but I’ve read where some people have used a much less expensive base such as Vanicream, which can be found on Amazon at the link below.
Amazon.com
Other popular bases for hormone creams that are known to work are HRT base, Pentrovan, Atrevis Hydrogel and a few others, but PhloJel Ultra was easy for me to obtain and its been proven to work, and that’s why I went with it.
Here’s some videos from Dr Keith Nichols of Tier One Health in regards to the testosterone cream he’s been prescribing for his patients for a number of years with very good success. I believe his cream is compounded with HRT base, but I wasn’t able to obtain it and that’s why I didn’t use it.
- YouTube
- YouTube
- YouTube
- YouTube
If you’re interested in making your own base with good bioavailability, then I’d recommend reading about the use of Ethosomes in transdermal delivery systems to start with.