Dr. Huge ... DNP, SARMs

[Michael Scally MD]

UK raids uncover suspected suppliers of deadly diet drug.
UK raids uncover suspected suppliers of deadly diet drug

A series of raids in northern England has uncovered an operation suspected of selling a deadly fat-burning chemical used by bodybuilders that has killed eight young people in Britain in the last two years.

Around 11 kilos of the chemical 2,4-dinitrophenol, known as DNP, was found last month at premises in Wigton, Cumbria, alongside other legal supplements and equipment that could be used for making tablets.

The premises are believed to be used by a company called Enhanced Athlete Europe, set up by a flamboyant ex-lawyer turned bodybuilding star who calls himself Dr Huge and has his own YouTube channel on which he extols the virtues of “the world’s most dangerous fat loss drug”.

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[MisterSuperGod]

And to that point I'd agree with you. But like you stated. Those who are not educated about it's dangers, or those popping them like hydroxycut are the ones at risk. I'm not saying it can't be run responsibly. I'm saying 99% of people should stay away from it because they fail to understand just how serious a overdose can be. And if they do overdose it's probably to late. To each their own. Just not my thing.

People can overdose on Tylenol just as easy, you know?

 

[Docd187123]

I will agree that when researching it most(not all), seemed to be individuals taking to much. Unfortunately they also had mislabeled amounts from some manufacturers of it. But I love you Doc and know your responsible. And we both know where each other stands on the issue. I thought the asshole comparing it to Tylenol was a bit of a reach though. And yes Doc half were from exposure.

I learned long ago your opinion won't be swayed on this topic and I will not try to change it lol. I honestly don't care if people never want to run it, I just get bothered when certain people misrepresent it. No harm no foul 'Cane

 

[janoshik]

Thank you guys for compiling the info in a single thread.

 

[hurricane]

I learned long ago your opinion won't be swayed on this topic and I will not try to change it lol. I honestly don't care if people never want to run it, I just get bothered when certain people misrepresent it. No harm no foul 'Cane

I know bud. You and I are fine. I love you bro(a little homo). LOL. I understand your point and you understand mine. People like you can run it safely because your not a jack off. I do think Dr. Huge may be fukd in civil court over the deaths. He may not go to jail, but I'd be shocked if family members of the deceased don't sue in civil court. Although I don't know how England operates their judicial system. Doc I'll try to link the pictures and interview of this guy from England who doubled his dose to get a beach body. Ended up having chunks of muscle removed from his quads. Fukin nasty. But he did take to much. Hope all is well Doc.

 

[hurricane]

People can overdose on Tylenol just as easy, you know?

You shut your mouth!! LMAO! I'm trying to keep my BP down Damn it!!

 

[TRT]

Aw come on man that's no fun!
That sounds like a fucking quitter to me!

I was actually going on lunch and wouldn't have been here to defend myself. Ha

It's fine for members who respect each other to disagree. We all have different views on what risks were willing to take. But the douche with the Tylenol comment can suk a D.

I actually did a lot research on Tylenol for a class paper. That's really the only reason I commented on why it's harsher then people think, not saying it's harmless or harmful. Just saying...don't hurt me.
Lol jk.
You guys did come out of gate real fast though. That guys had some pretty shitty comments in the past. I'm sure he's from another board just trolling here like I do to other boards. What?! Who said that? [emoji6]

 

[hurricane]

I was actually going on lunch and wouldn't have been here to defend myself. HaI actually did a lot research on Tylenol for a class paper. That's really the only reason I commented on why it's harsher then people think, not saying it's harmless or harmful. Just saying...don't hurt me.
Lol jk.
You guys did come out of gate real fast though. That guys had some pretty shitty comments in the past. I'm sure he's from another board just trolling here like I do to other boards. What?! Who said that? [emoji6]

LMAO.

 

[Ironlyfe80]

From what I found googling..64 people have been reported to die from DNP since 1918. 36 of those were in France in the 30s from working in munitions factories. Most recent deaths seem to have been women on extremely high doses.

 

[hurricane]

From what I found googling..64 people have been reported to die from DNP since 1918. 36 of those were in France in the 30s from working in munitions factories. Most recent deaths seem to have been women on extremely high doses.

Your pretty spot on. There's a few more males that I found, and 3 other females. But that's pretty much what I found. I had to dig a little deeper through DNP deaths in Great Britain. It's difficult though because what I found is anyone who was hospitalized for dnp was also thoroughly screened for other drugs. For instance there was a male taking anadrol and test with dnp. So the coroner wouldn't label it a dnp death. It's really hard to find exact numbers on it.

 

[SteroidsBro]

Isn't tony huge really only full of shit when he talks about sarms? He seems like a pretty good guy. Just sleazy with women. He never says anything negative about anyone. His attitude is always positive. It's at least a little bit entertaining watching his videos.

 

[FiEnD]

Isn't tony huge really only full of shit when he talks about sarms? He seems like a pretty good guy. Just sleazy with women. He never says anything negative about anyone. His attitude is always positive. It's at least a little bit entertaining watching his videos.

It's his terrible advice that's most disgusting

 

[SteroidsBro]

Ok, he's a piece of shit.

 

[Xlgx]

He’s a lawyer for crying out loud. What more needs to be said lol

 

[Kracken]

So just some thoughts on DNP from someone who is not an expert, has never used it and has only read about it, although with an intense curiosity...

Regarding how many people it kills or seriously injured as a percentage of those who use it, I don't think we can know this. It's difficult enough to know how many people have been killed by it. It's much more difficult to know how many people have been injured by it and I think it's impossible to know how many people have used it. It's not helpful to know that "66 people have died from it since 1918" (or whatever). Is that 66 out of 10,000 or 66 out of 10,000,000?

It seems to me that there are three issues with taking DNP, two of which were discussed in that video:

1 - The closeness of the effective dose to the lethal dose
2 - The fact that it builds up slowly and accumulates in the body, has a relatively long half life and people don't understand the importance of this.

And what was not discussed:

3 - It can't be sourced reliably. For most people, who really knows what's in it, where it came from and so on. It's an industrial chemical, not something manufactured for human consumption.

So it would seem that if this stuff were manufactured in a real pharma lab and administered under close supervision by someone who really understands it (like - a doctor) the risk would be highly mitigated.

But none of this is true, so there is risk and the risk / reward ratio seems pretty unfavorable. Risk items 1 and 2 above can be mitigated through education, but for the vast majority of people, I don't see how to mitigate item 3. Unless you know what's in it it's hard to dose it. If it's hard to does it, well item 1 above can't be mitigated.

And then, who knows what the long term impact of it is for those who have no apparent problems with it. This as also mentioned in the video. So maybe short term gain, but long term...

It would seem though that for those who use it right it does what people want. I have yet to see anyone complain that DNP didn't take fat off. So too bad the FDA and a drug company can't find a way to make this work. Maybe people would stop using it illegally.

 

[MrRippedZilla]

And then, who knows what the long term impact of it is for those who have no apparent problems with it. This as also mentioned in the video. So maybe short term gain, but long term...

It would seem though that for those who use it right it does what people want. I have yet to see anyone complain that DNP didn't take fat off. So too bad the FDA and a drug company can't find a way to make this work. Maybe people would stop using it illegally.

A small note re long term use: at moderate doses it appears to beneficial based off of animal/in vitro data. For example: DNP, mitochondrial uncoupling, and neuroprotection: A little dab'll do ya. - PubMed - NCBI

This makes sense if we understand what a mito uncoupler does and keep in mind that everything has a dose-response curve. Hint: activating the bioenergetic stress response through UCPs does ALOT of good things.
It's also being looked at alongside things like caloric restriction to enhance quantity of life. Again, just some examples of what the researchers are thinking here and it certainly isn't DNP long term = bad. The uncoupling protein (UCP) & peripheral neuropathy (PN, the biggest real risk with DNP) thing is also begging for more research but I digress.

Instead of speculating, or exaggerating as many do, what we should all be advocating is for more quality data. That is how we get answers, not through wild assumptions.
It frustrates the fuck out of me that I have to go into technical, weak ass, data (animals/in vitro, etc) in order to put the pieces of the puzzle together and then repeatedly experiment on myself to see what's up. It's such an inefficient way to look into what is obviously a pretty interesting drug.

 

[Docd187123]

So just some thoughts on DNP from someone who is not an expert, has never used it and has only read about it, although with an intense curiosity...

Regarding how many people it kills or seriously injured as a percentage of those who use it, I don't think we can know this. It's difficult enough to know how many people have been killed by it. It's much more difficult to know how many people have been injured by it and I think it's impossible to know how many people have used it. It's not helpful to know that "66 people have died from it since 1918" (or whatever). Is that 66 out of 10,000 or 66 out of 10,000,000?

It seems to me that there are three issues with taking DNP, two of which were discussed in that video:

1 - The closeness of the effective dose to the lethal dose
2 - The fact that it builds up slowly and accumulates in the body, has a relatively long half life and people don't understand the importance of this.

And what was not discussed:

3 - It can't be sourced reliably. For most people, who really knows what's in it, where it came from and so on. It's an industrial chemical, not something manufactured for human consumption.

So it would seem that if this stuff were manufactured in a real pharma lab and administered under close supervision by someone who really understands it (like - a doctor) the risk would be highly mitigated.

But none of this is true, so there is risk and the risk / reward ratio seems pretty unfavorable. Risk items 1 and 2 above can be mitigated through education, but for the vast majority of people, I don't see how to mitigate item 3. Unless you know what's in it it's hard to dose it. If it's hard to does it, well item 1 above can't be mitigated.

And then, who knows what the long term impact of it is for those who have no apparent problems with it. This as also mentioned in the video. So maybe short term gain, but long term...

It would seem though that for those who use it right it does what people want. I have yet to see anyone complain that DNP didn't take fat off. So too bad the FDA and a drug company can't find a way to make this work. Maybe people would stop using it illegally.

Maurice Tainte, a clinical pharmacologist back in the 30s, estimated that DNP usage was around 100,000 people back then. Add in the number of people who used it when it was available OTC plus the people who've used it since and you have a number between 10,000 and 10,000,000 that you listed.

As you said, risks 1&2 can be mitigated through education and strict monitoring of body temps. In the clinical trials, the researchers stopped administration of the DNP or reduced the dosage drastically if at any point the patient's body temp went above 99.1-99.3 deg F or if breathing became significantly labored. The uneducated never do this. They don't even check their boy temps but a similar argument could be made for the guy who shoots slin and doesn't monitor blood glucose.

There was one guy who you could source DNP from reliably. It was his "thing". He has since retired unfortunately.

The risk/reward seems skewed to you but everyone values their risks and rewards differently. I think it's an amazing drug that nothing else comes close to touching. It's in a league of its own. That doesn't mean I go around recommending it to ppl, bc I don't, but it does mean that when I'm looking for an edge that no other drug or dieting protocol can give me, I'll reach for the DNP.

A drug company is trying to make it work in a different light. They're looking at a time released version as a cure for diabetes.