What’s up brother man! Everything good here just been crazy busy! So sorry for slow reply lol.
Hope you are doing well too!
You know when you have taken too much b-6 when hands get tingly. That will subside after you back dosage down or come off the dosage completely. But generally 4-8 weeks is plenty you can even run it along side your cycle if one chose too.
As far as L-methyfolate goes it’s about as good as it gets honestly. It’s the end product of digesting folic acid pretty much or the end product of b-9 if that makes sense both peas in a pod to say.But yeah, if you are taking for depression I would pair that with vitamin d3 with dosage of d3 between 10kiu-20k iu. And I would suspect the depression to start becoming better and more easily managed in a decent time frame.