GH Antibodies

[Billbo98]

My reasoning? Misquote, yeah?

Whoops yes sorry

 

[Avies48]

I’m a non filterer and have had 0 issues. My china man’s material is 99.91% pure though. What is the major concern with filtering your GH?

Well shieeet ive been searchin high and low for yeaaars for a 99% gh…

 

[Photon]

How would we even isolate the result to a cause?

Is it the (1) product, (2) filtering , (3) concentration or (4) poor genetics?

 

[Billbo98]

Well shieeet ive been searchin high and low for yeaaars for a 99% gh…

lol pm me

 

[IndividualMan]

How would we even isolate the result to a cause?

Is it the (1) product, (2) filtering , (3) concentration or (4) poor genetics?

just do filterers vs non filterers, search for people who buy off the same supplier (lobster probably, hes been steady in quality or maybe one of the three letter sources) and who woudl be willing to contribute by testing this value+sharing it to someone collecting all the data.

If they get from the same source, tell them to do about 12IU/ml if big chinese like QSC/SSA/WWB 36IU, or 6IU/ml if lobster (or smaller chinese GH vials)

then take note of their IU/day

if genetic outliers are present, sucks to suck i guess. hopefully it wont be enough to fuck the data

even if we just get a handful in each group, the data would be nice to have+you can learn from it if there are glaring differences.
lets just hope the test is not too brutally expensive.

 

[J-Key]

I’m a non filterer and have had 0 issues. My china man’s material is 99.91% pure though. What is the major concern with filtering your GH?

Hey man, can you dm me

 

[Billbo98]

Hey man, can you dm me

Sound like a fed

 

[nobu156]

Couple of misconceptions here.

rHGH (Somatropin) is much cleaner than cadaver growth hormone in that it’s “purer” GH, but early formulations still caused a lot of aggregates to form, triggering antibodies and the loss of effectiveness, sometimes lasting long enough that the growth window for a short child was lost. This was a well documented problem in the early 2000s:

View attachment 369964

In fact, because pharma hadn’t yet done much work to protect against aggregates forming, 1st generation rHGH formulations produced almost the same level of immunogenicity as the last generation of highly purified cadaver GH.

View attachment 369965

You don’t hear about it now, from medical sources, because pharma has gotten very good at formulating and controlling storage conditions to prevent aggregation. The FDA is psychotic about making sure it’s not a problem.

Somatropin didn’t change. The rHGH molecule is still the same as it was in 2003.

The reason rHGH immunogenicity fell off the map is because excipient formulations were carefully designed to prevent aggregation.

UGL does basically nothing to prevent aggregation. To do so, you’d have to start with using a specific amount of water in order to even known how much of each excipient in the “recipe” would be needed, not the random amounts we all use.

How often does pharma GH become visibly cloudy? How about UGL?

Every label on pharma Somatropin has dire warnings to not use cloudy GH.

It’s not because it’ll kill you, or even cause any noticeable symptoms. It’s because aggregates can build an immunity to rHGH with potentially terrible consequences for someone, like a growth stunted child who loses their chance, or an adult who produces very low or no GH, and becomes very frail and sick if rHGH stops working.

Someone using rHGH as a PED is very unlikely to know if it’s working as it should or lost 75% of its effectiveness over time. IGF-1 response is all over the place. Is it me? Is this batch bunk? Is it my e2?

Because it’s not life shattering like real GH deficiency, even if immunity unknowingly develops, how would the UGL user know?

In medical treatment they know when rHGH starts losing efficacy because children start growing slower (“losing height velocity”). Adult GH deficiency patients start accumulating fat quickly, lipids get progressively worse. With UGL it’s practically all down to feels as to how well it’s working.

We know aggregates are the main driver of rHGH immunogenicity. It happened early on with pharma rHGH.

We know UGL aggregates frequently, often it’s so bad we can literally see it (and 90% of the time we can’t). Modern pharma rHGH doesn’t because of the protective excipient formulations. They’re not adding 5, 8, 10 ingredients in precise amounts for no reason.

Is there something special about UGL aggregation that means it doesn’t cause loss of efficacy even though aggregation in pharma rHGH clearly does?

It’s like holding up a gallon of pasteurized milk from the grocery store and saying “no one gets sick from drinking milk” as evidence drinking it straight from the farmers bucket is the same.

The shear amount of good you’ve done on here is wild man, thank you.

Would it be advisable to recon a whole kit, filter it all into a single sterile vial and just pull from it? Say it was a 10x10 kit and pulled 2iu/day. Or would that be way past the shelf life for the reconstituted substance

HGH is a fuckin pain.

 

[Ghoul]

The shear amount of good you’ve done on here is wild man, thank you.

Would it be advisable to recon a whole kit, filter it all into a single sterile vial and just pull from it? Say it was a 10x10 kit and pulled 2iu/day. Or would that be way past the shelf life for the reconstituted substance

HGH is a fuckin pain.

Nah, it’s almost effortless once you’ve done it a few times.

After you reconstitute like usual, it takes under a minute to draw into a 3ml syringe, attach the filter, and inject into a new vial (the original vial if you must, it’s still an improvement over not filtering), and you’re done.

Reconstituting one vial at a time is preferable, but 10 days worth is reasonable, so 2 vials in your case of 10iu vials and 2iu/day dose.

That minute you invest guarantees sterility, elimination of inorganic particulate trash like glass shards, and meaningful or not (I argue it is), removal of the vast majority of aggregates.

 

[Dav1D3XT]

anyone who knows where to do gh test antibodies?

 

[MissedArmDay66]

anyone who knows where to do gh test antibodies?

Labcorp

 

[KOArtist]

Labcorp

Couldn’t find it via Marek/Labcorp, do I have to go directly to Labcorp?

 

[Ghoul]

The only way to get it for $65 that I’m aware of is to join Fitomics (but you can join then quit, with a full refund of the membership fee in one case):

Research Labs Insider | Unlock Lab Insights — Fitomics

Explore detailed biomarker analysis and join an exclusive community with Research Labs Insider by Fitomics. Compare plans and choose the best fit for you.

www.fitomics.org

You can go with 1 month of the standard plan ($30), get your (very cheap) labwork and cancel if you don’t want to keep it, or 1 month of the “premium” plan ($49) get your labs, and get a full refund of the $49 if you cancel.

A little bit of a pain in the ass, but everyone else wants $165-225 for that test. And Fitomics is very cheap for the other bloodwork we usually have done, and no $10-15 draw fee either.

 

[Photon]

Couldn’t find it via Marek/Labcorp, do I have to go directly to Labcorp?

Don't go Marek.
It's one of the most expensive.

If you do sign up for Fitomics, you can buy labs in advance. You do not need to be an existing member to do the labs once you've bought it. They send you a form via email after purchase and you just bring it to a LabCorp. You can buy a few months worth of labwork upfront in order to get the most out of the membership fee.

Post in thread 'Basic/Affordable/Comprehensive Bloodwork'

Nov 28, 2025

Latest comparison as of 28Nov

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[Klax]

Nah, it’s almost effortless once you’ve done it a few times.

After you reconstitute like usual, it takes under a minute to draw into a 3ml syringe, attach the filter, and inject into a new vial (the original vial if you must, it’s still an improvement over not filtering), and you’re done.

Reconstituting one vial at a time is preferable, but 10 days worth is reasonable, so 2 vials in your case of 10iu vials and 2iu/day dose.

That minute you invest guarantees sterility, elimination of inorganic particulate trash like glass shards, and meaningful or not (I argue it is), removal of the vast majority of aggregates.

Ghoul, thank you for all the knowledge I've learned from your posts. Quick question - do you by chance have a writeup somewhere on this forum that details the supplies needed for the filtering? I have dug through your post history and haven't come across anything. I've never filtered my GH, but this sounds easy. Thanks in advance.

 

[Ghoul]

Ghoul, thank you for all the knowledge I've learned from your posts. Quick question - do you by chance have a writeup somewhere on this forum that details the supplies needed for the filtering? I have dug through your post history and haven't come across anything. I've never filtered my GH, but this sounds easy. Thanks in advance.

Here ya go:

(You can choose needles up to 23g with the 3ml syringes)

Feel free to ask any questions.

(Click the POST IN THREAD… text to see the whole post)
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Post in thread 'HGH Purity and dimer'

Feb 19, 2025

Great stuff. Is PeptideTest a cool place to get these filters, etc?

Better deals elsewhere:

Buy Ultra Spec Sterile 2ml Clear Sealed Glass Vials at wholesale prices

In order to receive vials in sealed shrink wrap boxes, please order in multiples of 25

www.medical-and-lab-supplies.com

3ml with 18g needle:

BD Luer-Lok Syringe with PrecisionGlide Needle, Box of 100 (Click for available sizes)

BD Luer-Lok Syringe with PrecisionGlide Needle, 100 per Box BD Luer Lok Syringe Tip with PrecisionGlide Needle: Becton Dickinson and Company: PrecisionGlide Hypodermic Syringe with needle combination. World's sharpest needle is combined with BD's clea

www.medical-and-lab-supplies.com

or get syringes without needle and use these, the ideal peptide reconstitution needles...

• Ghoul

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