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You’re going off topic again buddy, the point of these thread is not accommodate your lies and complaints.Unfortunately these clowns have been successfully to a degree. The number of members who DM me rather than post here is an indicator of how effective the intimidation of these idiots that wear their ignorance as a point of pride has been.
They have no interest in "harm reduction" for the people most interested in this thread. They think those in here looking for accurate info on using GLPs for to improve their health, rather than to tweak their appearance the way they do, are "fatty trash", less then them, and deserve nothing but being unhealthy.
The irony is most of these guys are losers by every other real life metric. More likely to be digging out old cesspools or power washing dog shit off decks by the order of some fat guy than leading a company or being top in any field.
Not so much OOS - just none in my dose range for domestic warehouse. International will take forever plus the reta is otw. Got a good dose/ frequency of it alone? Also I’m not doing it super long term just don’t want a lapse in my cut here. So thats the protoco I am running with for nowI don't see a problem with it. Reta is GLP, GIP so it's "Tirz" with glucagon added. I just wouldn't want to get committed to a compound that's far less cost effective, and still has some questions about what glucagon is going to do long term. It's not even FDA approved yet.
If you think Tirz is out of stock though you should be checking other suppliers. It's widely available.
Not so much OOS - just none in my dose range for domestic warehouse. International will take forever plus the reta is otw. Got a good dose/ frequency of it alone? Also I’m not doing it super long term just don’t want a lapse in my cut here. So thats the protoco I am running with for now
Reta is a superset of Tirz, so it's not like you're going backwards. Just be aware of the consequences of stopping and restarting use. Gear induced liver damage, heart remodeling and arterial plaque accumulation can be slowed, and even reversed by staying on a small maintainance dose below the appetite suppression level. You also avoid the "rebound" effect and most of all, the potential reduction in future efficacy
are there any indications at all for how long these 'downregulations' in efficacy occur?Reta is a superset of Tirz, so it's not like you're going backwards. Just be aware of the consequences of stopping and restarting use. Gear induced liver damage, heart remodeling and arterial plaque accumulation can be slowed, and even reversed by staying on a small maintainance dose below the appetite suppression level. You also avoid the "rebound" effect and most of all, the potential reduction in future efficacy.
I wonder if there is any science behind micro-dosing a GLP. I saw a few videos by users of the drugs who said more stable levels but no real evidence. If it make the user feel better whether its psychological or actually physical more power to them.Also some people do it twice a week versus once, thoughts?
are there any indications at all for how long these 'downregulations' in efficacy occur?
@iris, I want to be clear, I don't think you're coming to this debate with ill intent borne out of the same contempt as many of the commenters.
Declan, by far the smartest of the anti-GLP crew, makes compelling, "common sense" arguments that trigger the knuckle draggers who see their visceral "fattie hatred" justified by reasons they could never articulate themselves, to crawl out of the woodwork. His statements about "too good to be true", or "better to avoid pharmaceutical interventions" are actually all good general points that I follow myself, in the absence of evidence to the contrary. I prefer to let a few million other guinea pigs take the lead, since we've seen some awful outcomes from previous "miracle drugs". Drugs that are actually beneficial to be taken indefinitely, instead of being something one should try to use for as short a time as possible are the rare minority.
That's the crux of the matter, however. These aren't some novel "miracle" drugs that just appeared in the last few years. The evidence of safety and benefits is not only substantial, it's overwhelming. By the same standard, ibuprofen is cyanide in comparison. GLPs taken even when not used for weight loss, appear to improve the long term health of nearly every organ and extend life.
It's understandable that most people don't have the time to really dig into this. Some of the worst, most emotionally heated opposition to GLPs came from general practitioner doctors, of all people (mostly very fit ones). Luckily their numbers have been shrinking in the face of so much evidence they look stupid to their colleagues. You can sense the crumbling opposition even here, on Meso. It's far less of a hostile place to GLPs than just 6 months ago.
What's taken the place of the "don't be lazy just eat less move more" narrative is the more nuanced "use it if you must" but just as a "crutch" narrative.
That's the last stand of resistance to the ever clearer science connecting genetics, hormones, and their influence over behavior, in an environment of easily available, often poor quality food to feed this built-in "addiction" as being the root cause of obesity. Not some mass collapse in willpower worldwide that's only avoided by the best people who will themselves to a lower BMI, permanently. Yes of course individual choices play a part. Yes bodybuilders set a great example of the care and discipline that should be taken regarding nutrition, and many other aspects of health the population as a whole should learn from. Not necessarily motivated by health, after all, if a twinkie and ice cream diet led to a great looking body that would be the standard, but nevertheless, good looks and health track pretty closely together. Carefully managed nutrition is seen in those who've been most successful with GLPs, putting it into practice once they don't have to battle with "food noise" every moment of every day. The demand for healthier food by GLP users is changing what people are buying, for those paying attention, and companies are
https://apnews.com/article/wegovy-ozempic-zepbound-obesity-0d2b4e3f055dfd1b02a1d330db805c52
the tongue in cheek sarcasm
his 20yr old American Asian gf in Thailand and f her brains out with his 20" python, while burning $100 bills to light up his cigar WHILE scuba diving.