Giant Semaglutide Thread (and other GLP-1 / GIP agonists)

[Doodle]

Wanted to create a thread where everyone can post their experiences with different sourced Semaglutide.

Who are you using?
Pharma vs non?
Dosage?
How long have you been taking it?
What are your thoughts?
Have you lost weight?
Side effects?
Oral vs injection?
Tests?

 

[Nidus]

I am also quite tired and demotivated on Tirz. On Reta, on the other hand, I have more energy and the desire to do more things during the day. A noticeable and interesting difference.

Yeah man I take such nice dumps, I even stopped using psyllium husk because is completely not needed.
With tirz or sema I was shitting rocks on a good day, after a cheat day I was experiencing a prison rape while taking a shit

Yeah the glucagon makes some stuff a bit counter intuitive or to be more blunt not really understood on my part and if you read online even the medical field has still a lot to understand about glucagon mechanism etc but it works... In some funny magic ways xD

The insulin sensitivity part makes it more appealing to me, currently on 10mg Tirza e5d but surely will try out Retra once i can get my hands on from a EU Domestic source that tests their stuff.

 

[phenominal34]

I’m also loving Reta, the dam skin sensitivity is annoying tho.

 

[Sampei]

What volume is she using for her 5mg? 0.5ml?

Reconstituted with 3ml so I think it's 0.3ml for 5mg

 

[Sampei]

I’m also loving Reta, the dam skin sensitivity is annoying tho.

I was having full blown skin sensitivity and was driving me crazy I almost stopped it... Now it went away. So hang in there it will get better

 

[phenominal34]

I was having full blown skin sensitivity and was driving me crazy I almost stopped it... Now it went away. So hang in there it will get better

Good to know and look forward to, thanks

 

[Sampei]

Good to know and look forward to, thanks

Some ppl says zinc supplement helps. No clue if is true or not but I was taking it anyway because I need it to avoid getting copper level too high as I'm injecting GHK-CU ED

 

[Ghoul]

Reta has a much better insulin sensitivity improvement than tirz. 39% improvement in the diabetes trial, 52% improvement in the obesity trial. For comparison in the Surpass-2 trial tirz only has a 24% improvement for diabetics and I have no info for obesity.

Reta’s GCGR targeting causes depletion of hepatic glycogen stores. The muscular stores are unaffected by this action.

Is there a link to the 52% improvement study? I see. to be missing it.

 

[Sampei]

Is there a link to the 52% improvement study? I see. to be missing it.

https://diabetesjournals.org/diabetes/article/73/Supplement_1/266-OR/155164/266-OR-Retatrutide-an-Agonist-of-GIP-GLP-1-and?utm_source=perplexity

 

[WindonSea]

Given all the drama in their thread with bunk gear, bad shipping, lack of communication and other reports i'd stay with other sources such as Opti.

Thank you for this. I actually already ordered and received the product. The bunk LipoC thing happened right after I ordered. Ahhh..lol.

 

[BigNewb]

To add my own experience with pharma Tirz and Sema. I've found that high estrogen can easily overpower the fullness and filling nature of both. It's one of the only signs I have of high E2, and a slight affinity for sweeter foods.
Within a few hours of arimidex or Aromasin, the fullness and lack of desire to eat from Sema and Tirz comes right back. On .25 or .5 of Sema and 2.5 or 5 of Tirz.
I'm curious if Equipoise has a similar effect for me.