Help with Weightloss (Girl)

[Lunex]

Hello Meso!

I’m on a journey to lose some weight and would love to gather some tips and guidance. If anyone has experience with effective methods for weight loss
Any recommendations on what to use and how would be incredibly helpful as I embark on this journey.

I'm not scared of needles
Ozempic/WeGovy sounds too expensive.

Would any recommend Cagrilintide / Cagrisema over Semaglutide or Tirze?
I wanna start of low dosages for the first 2 months, unless there is not alot of side effects or nausea.

Stats:
Woman
23 Years Old.
Height: 155 CM
Weight: 63 KG

Goal:
Weight: 53-55 KG

Thank you in advance for your support!

 

[BuildABro]

Not sure what that one is. Another amphetamine analog I assume?

I admittedly experimented with adderall recreationally back in my college days. Umm yeah, food was not a high priority

It makes sense as it definitely gives energy and inhibits appetite. I’ve seen some strong meth heads lifting buncha copper that weighed twice as much as them lmao. In all seriousness I felt like phentermine was a good weight loss option for people that had a hard time losing weight. It made me feel like hell after it wore off so I stopped. But it definitely suppressed appetite.

.

 

[iris]

But you did not think diet and exercise alone could do it

It makes sense as it definitely gives energy and inhibits appetite. I’ve seen some strong meth heads lifting buncha copper that weighed twice as much as them lmao. In all seriousness I felt like phentermine was a good weight loss option for people that had a hard time losing weight. It made me feel like hell after it wore off so I stopped. But it definitely suppressed appetite.

As much as I like you, you realise this was started by a 23 TWENTY THREE YEAR OLD girl.
And the other person that is replying to you, who I am sure is much older than both you and her.
I am speechless.
Even as a joke, this is just s***

 

[JustMe18]

As much as I like you, you realise this was started by a 23 TWENTY THREE YEAR OLD girl.
And the other person that is replying to you, who I am sure is much older than both you and her.
I am speechless.
Even as a joke, this is just s***

Sorry, I thought it was a joke when the reply to sound advice he gave her was, “Thanks, but I’m looking to inject some shit.” Went on a side convo discussing phentermine and the appetite suppression it provides, with a little joke about methamphetamine that looks to be in bad taste. However, phentermine is a pharmaceutical amphetamine prescribed to those who cannot lose fat easily just by themselves. They are monitored by a doctor at a clinic and it has shown successful. I am not too sure about anyone else’s age, I myself, 35, should’ve been a little more mature and ignored this thread. But hard to do when when I see that type of reply to someone who took time to give insightful advice.

 

[Sam312xx]

Why?

Lifestyle change is difficult. Behavioral change is difficult. From a purely rational point of view, I can take an obese person and offer them this intervention and correct the obesity in the environment in which they find themselves. They simply my have to commit to the intervention for the rest of their lives.

Given the epidemic of metabolic disregulation in this country, I see that as a perfectly viable option.

If lifestyle and behavior change were so easy to modify in a population, the obesity epidemic wouldn’t be.

So the question then becomes, what is ideal vs. what is sufficient to address the problem. We can all agree that in the ideal case an obese person changes their behaviors makes better food choices and exercises regularly. In these circumstances it’s entirely possible for someone to taper off a GLP-1 RA and with a great deal of effort maintain a healthy weight.

Regardless, that’s not the kind of guidance I would start with. I can say with some degree of confidence that it is sufficient for someone to start on a GLP-1 RA, escalate dosage until 1-2% per week of loss is occurring and then expect to taper down to maintenance and sustain that indefinitely. That’s the guidance that I would start with, following which I would suggest a protein target, resistance exercise and the importance of lifestyle and behavior change that with some effort will allow some to come completely off and sustain a healthy weight.

Correct me if I'm wrong but it seems to me that we agree on mostly everything, including the fact that the pursuit of not being on medication forever is ideal, but we differ on the starting point.

I emphasize trying lifestyle changes before resorting to medication, or using a combination of lifestyle changes and medication, but with the ultimate goal of going off medication if the person can maintain their weight through exercise and nutrition.

Your approach sees medication as a first step to overcome the challenges in behavior change, with the possibility of tapering off once weight loss is achieved and habits improve.

 

[egruberman]

Your approach sees medication as a first step to overcome the challenges in behavior change, with the possibility of tapering off once weight loss is achieved and habits improve.

Your assessment is correct. I’ve come to this conclusion primarily as a result of the fact that lifestyle and behavior change have broadly failed at a population level prior to GLP-1 RAs. It’s certainly possible at an individual level but still unlikely.

I speculate that with some success at changing body composition using drugs, folks may then find lifestyle and behavior change to be easier. Certainly, it’s something that should be attempted, however I wouldn’t make it a barrier to entry in the slightest, because even if people choose to make no changes and get on these drugs forever, they will still have succeeded at becoming metabolically healthier.

 

[Sam312xx]

Your assessment is correct. I’ve come to this conclusion primarily as a result of the fact that lifestyle and behavior change have broadly failed at a population level prior to GLP-1 RAs. It’s certainly possible at an individual level but still unlikely.

I speculate that with some success at changing body composition using drugs, folks may then find lifestyle and behavior change to be easier. Certainly, it’s something that should be attempted, however I wouldn’t make it a barrier to entry in the slightest, because even if people choose to make no changes and get on these drugs forever, they will still have succeeded at becoming metabolically healthier.

There is no doubt that lifestyle changes are challenging, and it's true that not everyone succeeds with diet and exercise alone. However, starting with medication as the first and primary solution bypasses the opportunity for many individuals to discover whether they can manage their weight through behavior changes, especially when those changes are supported by proper education and support.

Also, relying on medication as a default solution without emphasizing behavior change from the start, can lead people to ignore the root causes of their weight gain. Medication alone, without long term habit changes, will not address other lifestyle related health issues, such as cardiovascular diseases, mental health issues, and overall lower quality of life, regardless of weight loss or the metabolic improvements you mentioned.

Medication is a powerful tool, but lifestyle changes should be prioritized or at the very least, pursued alongside medication. This creates a path to better long term health outcomes.

 

[bigMoJo]

Thank you. My own use of tirz isn't due to a lack of exercise or poor diet, but rather because I suffered a spiral fracture of the humerus, which has limited my physical activity and forced me to temporarily consume drugs that lead to weight gain.

View attachment 299291

How did u break your arm?

 

[egruberman]

Also, relying on medication as a default solution without emphasizing behavior change from the start, can lead people to ignore the root causes of their weight gain.

This is where I think your reasoning has gone awry. The medication, in and of itself will address the root cause of weight gain.

 

[Sam312xx]

How did u break your arm?

Car accident

 

[Sam312xx]

This is where I think your reasoning has gone awry. The medication, in and of itself will address the root cause of weight gain.

How so?

 

[HB_22]

I'm not scared of needles
Ozempic/WeGovy sounds too expensive.

What you mean by that? Just buy from China and it's literally 1-2$ for a weekly dose. Even for tirzepatide it's super cheap.

 

[Middus]

True, agree.

I think some people are just butthurt that in the not too distant future, obesity will not exist anymore. And some like to feel special by achieving great body fat etc.

If your whole life is about making other people feel jealous and suddenly everyone can be skinny, it must hurt lol.

People don't realize that it will be normal to be on all kinds of life altering medications someday.

Why waste so much energy staying lean when you can achieve the same with better health metrics by taking glp1 receptor agonists and the like. And guess what, you can use this energy to focus on better things in life like financial success, family, social life with friends, enjoying life...

Someone finally said it. It's mostly butt hurt. Not having enough obese people to feel better than, and worse yet, ex morbidly obese people that didn't spend 35hrs at the gym every week eating nothing but plain rice and chicken breasts before losing 200lbs

 

[BuildABro]

To me “I’m just looking to inject shit” summarizes perfectly the mentality that is responsible for not only weight gain but also for the abysmal public health outcomes throughout western society currently

It says to me “I am unwilling to put in any effort but I want positive outcomes”. That a person of this mindset finds themselves obese is hardly a surprise. Unfortunately my own millennial generation is well noted for this type of thing. Anything involving hard work is out of the question.

These are the folks I was alluding to farther up the thread that seem to be fundamentally incapable of making the types of changes required. Left unchecked they will continue to commit what is essentially a slow form of suicide by eating themselves to death.

So yeah, I am 100% on board with the notion that for some people these meds need to be perpetually administered. Treat obesity as a chronic disease and keep them on drugs for life. This would be to substantial public health benefit.

Sorry, I thought it was a joke when the reply to sound advice he gave her was, “Thanks, but I’m looking to inject some shit.” Went on a side convo discussing phentermine and the appetite suppression it provides, with a little joke about methamphetamine that looks to be in bad taste. However, phentermine is a pharmaceutical amphetamine prescribed to those who cannot lose fat easily just by themselves. They are monitored by a doctor at a clinic and it has shown successful. I am not too sure about anyone else’s age, I myself, 35, should’ve been a little more mature and ignored this thread. But hard to do when when I see that type of reply to someone who took time to give insightful advice.

 

[iris]

Sorry, I thought it was a joke when the reply to sound advice he gave her was, “Thanks, but I’m looking to inject some shit.” Went on a side convo discussing phentermine and the appetite suppression it provides, with a little joke about methamphetamine that looks to be in bad taste. However, phentermine is a pharmaceutical amphetamine prescribed to those who cannot lose fat easily just by themselves. They are monitored by a doctor at a clinic and it has shown successful. I am not too sure about anyone else’s age, I myself, 35, should’ve been a little more mature and ignored this thread. But hard to do when when I see that type of reply to someone who took time to give insightful advice.

I appreciate you.
Thank you for your message.

I have been reprimanded by a gentleman, here, that Ghoul and I derail stuff. This would not be the case, however.
I do want to reply to you.
So, give me a minute and I will write you.

Thanks.
X

 

[bigMoJo]

There is no doubt that lifestyle changes are challenging, and it's true that not everyone succeeds with diet and exercise alone. However, starting with medication as the first and primary solution bypasses the opportunity for many individuals to discover whether they can manage their weight through behavior changes, especially when those changes are supported by proper education and support.

Also, relying on medication as a default solution without emphasizing behavior change from the start, can lead people to ignore the root causes of their weight gain. Medication alone, without long term habit changes, will not address other lifestyle related health issues, such as cardiovascular diseases, mental health issues, and overall lower quality of life, regardless of weight loss or the metabolic improvements you mentioned.

Medication is a powerful tool, but lifestyle changes should be prioritized or at the very least, pursued alongside medication. This creates a path to better long term health outcomes.

Let's keep in mind that this is a "harm reduction" community. With that said, OP's first couple of posts indicated her intentions to "inject shit."
She even posted a peptide calculator with Sema dosage:

Should I use BAC Water or Sterile with Tirze/Sema?
Does it look correct?

Semaglutide Vial 5MG
Dosage 0.25mg
View attachment 299065

As a first response, @BuildABro you gave genuine good advice about pursuing diet and excercise. Now, I disagree with a 500 calorie defecit for a 5'0" 150lb woman - more like 2-250. But that's neither here nor there... OP clearly made her intention known.

Along comes @Ghoul and I'm sure recognized this "intent" (as smart as he is) and provided an abundance of "harm reduction" information. Usually, the community tells new members like OP, "Search Bar." But ghoul was generous.

Failing to realize this, @Sam312xx, you jump off with an intrepid argument. No offense, but it came across brash and hypocritical, since you yourself are "injecting shit." Honestly, we already know the argument you're making... yes, its better to lose fat without drugs first. And, who the heck wants to take any drug for the rest of their lives? It's kinda like a "Captain Obvious" thing.

But, don't get me wrong, an opposing argument is healthy. I just don't don't think you can swing at ghoul for this... "answer me." I'm not defending ghoul... he can most adequately defend himself (you should read some of the "gangland" battles he's had - likely why he hasn't responded to you).

You can also see, @egruberman laid out incredibly astute reasoning opposite to your argument. IMO, kinda blew your stance out of the water.

I'm not saying "don't disagree." However, I AM saying "look before you leap." Disagreeing is one thing, taking swings is another, right?

I hope your arm gets well soon, and success on your fat-loss journey.

 

[BuildABro]

Appreciate you taking the time for a quality summary of arguments put forth, @bigMoJo.

I'd say between all of us we have collectively covered all of the bases, with only minor deviations into silliness. So a new reader to the thread could check it out and then discern for themselves what resonates most with them.

As you can probably gather I tend to be more of a David Goggins type when it comes to these topics, but I always do get insight from reading other perspectives. Life would be awfully boring if everyone always agreed.

 

[Middus]

To me “I’m just looking to inject shit” summarizes perfectly the mentality that is responsible for not only weight gain but also for the abysmal public health outcomes throughout western society currently

It says to me “I am unwilling to put in any effort but I want positive outcomes”. That a person of this mindset finds themselves obese is hardly a surprise. Unfortunately my own millennial generation is well noted for this type of thing. Anything involving hard work is out of the question.

These are the folks I was alluding to farther up the thread that seem to be fundamentally incapable of making the types of changes required. Left unchecked they will continue to commit what is essentially a slow form of suicide by eating themselves to death.

So yeah, I am 100% on board with the notion that for some people these meds need to be perpetually administered. Treat obesity as a chronic disease and keep them on drugs for life. This would be to substantial public health benefit.

We are all a product of our experiences. These things shape our outlook and biases, conscious and unconscious.
Personally The statement about "wanting to inject shit" is loaded. Further down into the post, OP mentions GLPs and pricing and all, meaning some level of research has been done, about the category of stuff to be injected.

While talking to her about lifestyle change and calorie restriction is great, she has obviously made up her mind. Best either ignore if one doesn't agree with it, or advise on how to go about it. Remember the Reta+ DNP dude? even with all the insults and Jibes, bro is still at it. Documenting and posting and what not.

The way I approached it is that unlike gear or SARMS , GLP-1s have a relatively wide safety margin. What's the worse a miscalculated sema dose do apart from send her to the er with exaggerated GI symptoms? It's not like people that come here wanting to get big and are asking about blasting 800mg Test daily + 20IU HGH. That dampens the need for me to sound any alarm bells.
Finally, a cursory a glance at the calculations shows someone with a BMI that is barely overweight, and no where near obese. I support the use of GLPs by the OP. If one isn't winning the war between calories in calories out for whatever reason (age, metablolism, thyroid dysfunction, Broken arm ) Why not use readily available tools?
Besides. I have no proof that she is slobbering away on 5 large pizzas and gorging on deep fried Snickers. Op May just be someone that is watching the weight creep on slowly and wants to quickly do stuff before it gets out of hand.
The only part I disagree with Ghoul is with the life long use suggestion. I Personally, I feel that's for the "50yrs and pushing 450lbs" crew (in my opinion) Where you can't just get up and go, and even after the weight comes off, a lot of damage has happened to joints, organs, homeostasis, that merely eating healthy may not cut it, and exercise is limited. As research keeps showing though GLPS are good at aiding recovery of some of the damaged organs too.

Anyway, the point of my long winded diatribe is that individuals need to be addressed individually. Collective assessment of personal stories is sometimes unhelpful

 

[egruberman]

I tend to be more of a David Goggins type when it comes to these topics

This is a perfect example. If you listen to him, you realize, he is not well. There's something in him, driving him beyond all reasonable ends. At the very least, he is a genetic outlier, and more likely that coupled with some kind of trauma related to the abuse he experienced as a child.

Unfortunately, it would be difficult to replicate that kind of persistence in a normal, well-adjusted human.

How so?

Weight gain occurs as a result of caloric surplus. A GLP-1 RA will cure that calorie surplus.

It says to me “I am unwilling to put in any effort but I want positive outcomes”. That a person of this mindset finds themselves obese is hardly a surprise. Unfortunately my own millennial generation is well noted for this type of thing. Anything involving hard work is out of the question.

This is the human condition. It is not unique to your generation. To the extent that society evolves to address our needs and provide us with greater comforts, people will become less and less willing to do hard things.

The only part I disagree with Ghoul is with the life long use suggestion.

The reason for the suggestion, I believe, is that there is some evidence that stopping and re-starting may cause a reduction in efficacy.

 

[Sam312xx]

Failing to realize this, @Sam312xx, you jump off with an intrepid argument. No offense, but it came across brash and hypocritical, since you yourself are "injecting shit." Honestly, we already know the argument you're making... yes, its better to lose fat without drugs first. And, who the heck wants to take any drug for the rest of their lives? It's kinda like a "Captain Obvious" thing.

But, don't get me wrong, an opposing argument is healthy. I just don't don't think you can swing at ghoul for this... "answer me." I'm not defending ghoul... he can most adequately defend himself (you should read some of the "gangland" battles he's had - likely why he hasn't responded to you).

I'm not saying "don't disagree." However, I AM saying "look before you leap." Disagreeing is one thing, taking swings is another, right?

Personal choices don’t negate the ability to offer sound advice on a topic.

If "it’s better to lose fat without drugs first" were truly a "Captain Obvious" statement, the original poster to whom I replied wouldn’t have pushed the idea that permanent use of medication use as the primary and inevitable solution, comparing this medication to something like insulin for diabetics.

It seems ironic that you're calling me out for supposedly "taking swings," when the only person who actually resorted to direct insults was Ghoul, whom you seem to be defending.

I’ve remained respectful throughout the conversation, while that individual called people "pussies" and "knuckle draggers." If we’re going to talk about looking before leaping, it might be worth considering who’s actually crossing the line here.

 

[BuildABro]

Agreed as to civility, and admins here have made it pretty clear that this is no place for that sort of childishness.

Personal choices don’t negate the ability to offer sound advice on a topic.

If "it’s better to lose fat without drugs first" were truly a "Captain Obvious" statement, the original poster to whom I replied wouldn’t have pushed the idea that permanent use of medication use as the primary and inevitable solution, comparing this medication to something like insulin for diabetics.

It seems ironic that you're calling me out for supposedly "taking swings," when the only person who actually resorted to direct insults was Ghoul, whom you seem to be defending.

I’ve remained respectful throughout the conversation, while that individual called people "pussies" and "knuckle draggers." If we’re going to talk about looking before leaping, it might be worth considering who’s actually crossing the line here.