MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
Sorry to dig up an old post, but where can you source Tirz for that amount? Cheapest I've seen looks more like around 50 dollars per 5 mg.
SubparMarioBro
New Member
If only there was a place on this site where you could source stuff.
Ghoul
Member
The rules only allow source discussion in the Underground forum here. Just go there, look at the top (representing the most recently active) threads in both the "sticky" list at the top (those are vendors who are MESO sponsors) and the top threads in the bottom section (for non sponsoring vendors). .
Look for Tirzepatide kits (a kit is 10 vials). So a 30mg kit is 300mg,
Opened the fridge, did some math, and realized I’ve got 1310mg of Tirz to go before I even get to think about Reta. Not complaining - just saying, at this rate she’s basically a long-distance relationship. Bumping to 10mg/week next week to close the gap a little faster.
Damn, talk about life supply! I have the same with Primo.
Still got a ton of Tirz myself but also looking to swap to Retra in 5-6 months.
SpicyMeatball
Member
Pretty sure you’ll find the word “Advertisement” above or below that “news story.” If you don’t, you need to get your news from somewhere else
Ateam2023
Member
of course its an advertisement,, your point? I could care less about glp1 drugs , i thought it might be something a person could look into if they were interested, Have a Grateful Day,,
SpicyMeatball
Member
The point is that online shops selling bootleg ozempic to rubes are nothing new or particularly noteworthy. They’re not selling legit pharma pens without a script for $170/month (the claim in the ad) I can promise you that.
Ateam2023
Member
Your so Smart, excuse my level of ignorance,, Fucking WEENIE!
Ghoul
Member
That's normal for GLPs as you lose weight. A certain dose will get you to. a certain weight, then you have to increase to go down further. The people who've reached goal weight and stay on a maintainance dose for years don't feel anything, unless they start to regain weight, then physical and psychological appetite suppression effects return.
shouls I up my tirz? I've been on 5mg for 9weeks, the first 4 weeks were amazing, zero hunger amd craving, I could eat extremely clean, just meat, eggs, fruits and e
vegtables with no hunger and lost 15lbs, then my appetite started coming back and in the past 2weeks my binge eating issues amd chronic hunger have kicked back in full force.My weight is still relativly stable but as a result I'm hungry almost all the time again. I'm mostly afraid the loss off effectivness will keep happening as I uo the dose.
I do normal pharma protocol of 1 injection a week with a 1ml injection volume
vegtables with no hunger and lost 15lbs, then my appetite started coming back and in the past 2weeks my binge eating issues amd chronic hunger have kicked back in full force.My weight is still relativly stable but as a result I'm hungry almost all the time again. I'm mostly afraid the loss off effectivness will keep happening as I uo the dose.
I do normal pharma protocol of 1 injection a week with a 1ml injection volume
Ghoul
Member
It's almost certainly not losing effectiveness, you've just reached the "plateau" for that dose. To lose more weight increase the dose, which will push your "weight setting" lower. Eventually you'll plateau again, and then you would increase the dose again if you wanted to lose more.
Once at goal weight, you stay at that amount (or lower it slightly) as a maintenance dose and don't feel any appetite suppression effect (like now), unless weight increases, then the effects will return until you shed that weight.
Despite not "feeling" it, you'll still benefit from greatly increased insulin sensitivity and reduced inflammation, both of which will benefit your long term health.
the thing is that I'm fine with the weight I'm at, but I don't like that it's once again a struggle to control my appetite and my diet. I'd like to stay at my current weight but have an easier time with my diet and less cravings. mostly it's a cravings issue, if could eat clean I'd be fine with it, people say it's just a will power issue but idk because it's not like a craving that goes away. I'm costantly craviing sweet food /carbohydrates (even just fruit) 24/7 and it never goes away even after a latge meal, it had only gone away during those first 4 weeks of tirzepatide. I tried keto/carnivore diets but they don't help. during those first 4 weeks I could eat fruit and potatoes and it was fine, now I'm once again craving sugar 24/7 and even just eating an appleor strachy vegetables like pumpkin sets me off to binge eat. And when I'm on super low carbs even if I have enough calories training becomes miserable and I have zero motivation
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That’s something I’ve always been curious about - why it seems to work that way. In theory, someone should still be able to lose weight on a lower dose if they’re in a proper deficit, doing cardio, and training consistently. So I wonder if the idea of a “plateau” on GLP-1s has more to do with how people approach it.
Maybe it’s less about the drug losing effect and more about the behaviors around it - like relying on the appetite suppression instead of using it as a tool to build better habits. Not judging at all, just genuinely interested in how much of it is physiological vs psychological.
Ghoul
Member
The body has an energy homeostasis system. In other words, it wants to be a certain size/level of fat stores.
Below that it induces you to eat via physical and physiological mechanisms. Digestion speeds up. Sense of smell sharpens. Mouth waters. Increasingly invasive thoughts about food.
Above that level, digestion slows, food seems unappetizing, even the thought of "eating one more bite" can induce nausea.
Exogenous GLP hormones simply lower that "setting" your body wants to maintain.
All the "appetite suppression" effects are the same things you'd experience after gorging yourself to excess on a large meal by forcing yourself to eat beyond your appetite.
That’s a really clear explanation - thanks for laying it out like that. Makes a lot more sense now why GLP-1s feel the way they do. It’s wild how they mimic the “I’m way too full” state without needing to actually eat that much.
Also makes me wonder - do you think that “set point” is mostly genetic? Like, some people seem stuck at a certain weight no matter how hard they diet, while others stay lean without much effort. I guess GLP-1s help shift that point, but I’m curious how much flexibility we really have long-term.
