xrayphoton13
Member
I believe you are supposed to keep rHGH and secretagogues separated by at least 24 hours so I'm not sure if you are reaping any benefits combining them
MESO-Rx
Anabolic Steroids
Hexarelin vs ipamorelin vs tesamorelin...
- Thread starter Bigoldguy
- Start date
AlexDavis43
Member
Kinda hard to do with hGH, being that you'd be injecting it at least once every 24 hours.
there was a small study, in humans, that found hexarelin had a positive effect to LVEF in male volunteers. This effect appears to be a unique property of hexarelin.
You gotta be careful though, because it will spike prolactin at higher dosages.
All 3 of them can spike Prolactine. For me personally, Ipamorelin was the worst. 300mcg every evening for 3 weeks and my Prolactine was at 66. Stick to GH and run 3iu and you'll be off much better.
xrayphoton13
Member
Yeah you would have to pick either HGH or secretagogues. Like maybe workout days do HGH and non workout days do secretagogues. Or rotate HGH 4 months, off 2 months, on secretagogues two months then repeat
That sucks. The research I've read says Ipamorelin is the GHRP least likely to affect other hormones like Prolactin. All my labs have come back with low prolactin too. But everybody is different.
bigMoJo
Member
Thanks for bringing up this topic and posting this article. I did not see any of the rat trials as references in the article, or any other scientific evidence or data referenced. I did not do a seperate search regarding hexarelin used in rat trials. Basically, what I'm saying is that article is written without any proof to back up it's claims.The Effects of Hexarelin on the Cardiovascular System
In this condensed review, we discuss the evidence about the effect that Hexarelin has on the cardiovascular system. Read more here about Hexarelin.www.consumerhealthdigest.com
Explains it better than I could. For some of the results, it was administered IV but I believe the protective properties can be achieved with a long term daily dose.
Additionally, assuming everything in that article IS backed up, there is no comparative data pertaining to ipa and tesa listed. Maybe I've looked at this thread mistakenly.
I know in your post you link that article as simply an "explanation." However, how did you come to the conclusion that hexarelin is "better" than the other two, and/or provides improved cardiac function?
Moreover, I HAVE read before that hexarelin is "stronger" than ipa, but I would have to search that study again. I've also run hex and ipa myself... anecdotally, shit works very well, but definitely hex is more "potent" IMO.
Agreed, that article is trash.
This is good summary:
And yes, there are several studies you can reference, including at least five in humans:
You referred to Ipamorelin, Hexarelin, and Tesamorelin as if they were in the same group twice. Ipamorelin and Hexarelin are GHRP's, and Tesamorelin is a GHRH. So you can't do a strict comparison of Hexarelin to Tesamorelin because they work differently.
Some people combine GHRP's with GHRH because they have a synergistic effect when used together. On the GHRP side, Ipamorelin is probably the most common because it doesn't have the side effects of GHRP-2. Tesamorelin is probably the most common GHRH because it is actively prescribed medically (unlike CJC-1295, Sermorelin).
Some people combine GHRP's with GHRH because they have a synergistic effect when used together. On the GHRP side, Ipamorelin is probably the most common because it doesn't have the side effects of GHRP-2. Tesamorelin is probably the most common GHRH because it is actively prescribed medically (unlike CJC-1295, Sermorelin).
CraneKraken
Member
That's a nice sleep protocol. I have always struggled with sleep and it takes hours for me to settle down for the day. I've been taking melatonin for over 20yrs and it's always been helpful. I also take 500mgs of magnesium glycinate. On occasion I'll add 500mgs of magnesium oxide but the oxide often gives me the shits. My doctor now prescribes 100mgs of Hydroxyzine to help me settle down at night. I also take Gaba Pentin due to nerve damage from a major injury and surgery. The Gaba Pentin helps me slow down but seems to do little for deep, restful sleep. I also do a 6iu bolus of GH around 8 each night and the GH has helped me sleep deeper, once I finally hit that stage. The problem I have is it takes a really long time to hit that deep sleep stage and if I'm waking up to use the bathroom multiple times a night than it completely disrupts my ability to get deep restorative sleep -I do think that even on those rough nights the GH still helps make even the broken sleep more restorative.
With that said, I have a couple quick questions on your protocol.
- Does the 3000mgs of Magnesium cause you any bowel issues? If not, which type are you using?
- Do you find the injectable melatonin works better than tablets? Is it worth the extra injection and cost, or is it just a part of a blend?
- I've been really interested in giving DSIP a shot. How effective do you think it is compared to the other parts of your protocol? How long does a kit last you?
**Epitalon also looks like it could have some promise as a productive sleep aid. I may give that a shot along with DSIP.
I apologize for the long reply. Sleep is just a major issue for me and as a recovering opiate addict I have to be really careful about what I take to slow myself down at night.
Thanks, brotha.
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CraneKraken
Member
I wasn't aware of this. I just ordered some Reta and like I said in a previous post, I absolutely suck at sleep. I'm thinking I should order some DSIP today. I'm considering giving Epitalon a shot as well.
I use magnesium bisglycinate, never had any bowel issues.
Injectable melatonin kicks your ass really fast i noticed that after a few weeks using it the effects are less pronounced yet you still sleep well!
DSIP: Really nice peptide but i've build a tolerance up for it, so i had to increase dose every 2-3 days by 50-100mcg and would take major breaks i.e. 4-6 weeks on and 2-3 months off and deploy that usually just during strict cuts to sleep better.
Epitalon makes you sleep well for sure but i found that the effects dont last long and its quite pricey for a sleeping aids, also not something youre supposed to run year around as far as i know.
I'd say 4iu GH together with some DSIP should help you a lot.
Youre wasting money. You should read into these things and educate yourself. Running GH + CJC295/Ipa blend + another Somorlin/ipa blend dont do much.
Just run GH alone at this point.
bigMoJo
Member
This is my understanding from the available research as well... its one or the other... hGH or Secretagogues.
hGH shuts down natural production for, IIRC, about 24 hours. With natural productuon shut, what's the Ipa/cjc going to boost?
Its pretty much pointless and Secretagogues dont even come close to make the body produce 3-4iu esp. at the old age. Just stick with 4iu GH.
I think with Ipa you come close to 2iu at tops?
Yes, peptides and HGH can be taken together, but you should consult your local health authority for more information.
Studies on peptides and HGH
Studies on peptides and HGH
- A study found that combining growth hormone-releasing hormone (GHRH) and hexapeptide GH-releasing peptide-6 (GHRP-6) can cause a large increase in plasma GH levels.
- Another study found that coadministration of GH-releasing peptide-2 (GHRP-2), TRH, and GnRH reactivated the GH, TSH, and LH axes in prolonged critically ill men.
- A study found that hexarelin plus GHRH are synergistic and have potent GH-releasing activity.
- A study found that pretreatment with BPC 157 can enhance the effect of growth hormone in a dose- and time-dependent manner
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