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I heard someone say the other day that 6mg was the dose at which maximal hyperplasia occurs and that beyond that is diminishing returns, thus the use of that dose for HIV patients.

I quick review of the literature yielded nothing about hyperplasia. The 6mg dose was settled upon because it was the maximum tolerable dose on average for patients that needed an acute increase in lean body mass.

It seems there's a linear, dose dependent response with regard to reduction in body fat and an increase in lean muscle tissue anywhere from 1-6mg.
 
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