I think I am getting Gyno.....

[la_triathlete]

Hey guys-

I think I am in the process of getting gyno. I have a small lump under my left nipple, but nothing under my right nipple. I have just finished taking 100mg A50 (ED) and 150mg T. prop (EOD) for the last 6 weeks and am now starting on 150mg Tren (EOD)/ 600mg Primo (per week)/ 100mg Masteron tabs (ED) for the next 6 weeks.

I felt the lump about 1.5 weeks ago and started taking 30mg nolva ED (20mg at night/ 10mg morning). I am wondering if this is not the gyno I should be treating with the nolva, but the bromo. If taking nolva is the right thing, when should the lump start going away.

As you can imagine, I am a bit concerned. Is there anything else I should be taking other than the Nolva? Should I get some bromo? Arimidex?

best,

LA

 

[Neodavid]

Same thing happened to me, but if it's a LUMP, it's not gyno. That's just the gland responding to the estrogen. It makes the little puppy grow, to catch it up to the other side probably. Mine only happened on the left side too.

In my case it just went away after a while, and since you are taking novla, that should be fine. Doublecheck to make sure nothing you are on breaks down into progesterone, cause Novla won't help that. I think Deca is that way, but some pro will probably answer that part for you.

I just wanted you to know that lump isn't a problem. It gets a little sensitive as it's growing. My wife elbowed me there once with some pretty funny painful results.

No fear dude.

Hey guys-

I think I am in the process of getting gyno. I have a small lump under my left nipple, but nothing under my right nipple. I have just finished taking 100mg A50 (ED) and 150mg T. prop (EOD) for the last 6 weeks and am now starting on 150mg Tren (EOD)/ 600mg Primo (per week)/ 100mg Masteron tabs (ED) for the next 6 weeks.

I felt the lump about 1.5 weeks ago and started taking 30mg nolva ED (20mg at night/ 10mg morning). I am wondering if this is not the gyno I should be treating with the nolva, but the bromo. If taking nolva is the right thing, when should the lump start going away.

As you can imagine, I am a bit concerned. Is there anything else I should be taking other than the Nolva? Should I get some bromo? Arimidex?

best,

LA

 

[la_triathlete]

Same thing happened to me, but if it's a LUMP, it's not gyno. That's just the gland responding to the estrogen. It makes the little puppy grow, to catch it up to the other side probably. Mine only happened on the left side too.

In my case it just went away after a while, and since you are taking novla, that should be fine. Doublecheck to make sure nothing you are on breaks down into progesterone, cause Novla won't help that. I think Deca is that way, but some pro will probably answer that part for you.

I just wanted you to know that lump isn't a problem. It gets a little sensitive as it's growing. My wife elbowed me there once with some pretty funny painful results.

No fear dude.

Thanks for responding Neodavid! I forgot to say that I have been doing 300mg Deca for about 3 weeks. My sholder was bothering me, so I was shooting in my sholder to lube it up. But, I don't think that 300mg deca once a week will give me issues, or will it?

I know you say not to worry, but of course I can't help but worry just a bit. On a side/ personal note, my father was just diagnosed with male for breat cancer. So, you can understand why I am freaking a bit even though you say not to worry.

I hope the nolva will help, but if any of the pros think I should be a bit more agressive with this and take a course of Arimidex, I will do so. Like yours, my nipple is a bit tender, but only when I start touching/ squeezing it (wow, that did not come out the way I wanted it too, LOL). If it does not go away within the next 2 weeks, I will probably just go over to my doc and have them check it out.

looking forward to hearing from other folks,

LA

 

[eleven11]

Deca always gave me a knot under my rt nip. clomid got rid of it for me. nolva would be be better I guess. I don't do deca anymore for that reason and I haven't got it since............11

 

[N4cer]

Best thing I've found is run some aromatase inhibirot such as arimidex no matter what you run. Progesterone (Deca) won't cause gyno (in the VAST majority of people) without excessive estrogen at its side.

I'm extremely gyno prone, but .5mg adex and 20mg Nolva is a daily gyno preventer that works wonders.

 

[Deacon]

I agree it does not sound like gyno to me - is it real tender?

 

[la_triathlete]

I agree it does not sound like gyno to me - is it real tender?

It is ever so slightly tender, but that's probably because I keep touching it. Otherwise, its not tender.

My breast/ nipple don't look like they are becoming tits, so I am not sure if it is gyno either. However, I was not sure how people first realize they might be having gyno- i.e., do you guys start feeling a lump under your nipple like I am?

I will order some arimidex anyway just to be on the safe side.

For you guys out there that have had gyno, does it ALWAYS effect both sides (i.e., both nipples, breast tissue) or can it sometimes effect one side more than the other?

Since I started feeling the small lump on my left side, I have never felt anything wierd on the right side.

 

[Neodavid]

LOL....

Oh man, that's a GREAT line, sounds like something Austin Powers would say... "It is ever so slightly tender, but that's probably because I keep touching it. "

If you are taking Novla, I seriously doubt it's gyno. I was on 500 test per week and my left nip did the exact same thing yours is doing.

I was near the end of my cycle though. This time it started up again on a new cycle, but I took primrose oil in large daily (3x) doses (per an old juicer), and it went away.

I'm not sure primrose oil works, or works in the same way, I can only tell you what it did for me.

BUT, I had no novla, no arimidex, and was desperate (it's on order now).

I'm not sure on DECA what dose it takes, I just know Novla doesn't help progesterone gyno.

I'm not an old pro, this is only my second cycle, but figured it would help you to know the same thing happened to me, I did NOTHING, and it was fine. Since you are doing Novla, you should be good, and IF you check on the DECA and find it's a safe dose (do a forum search here), you'll probably be fine.

It is ever so slightly tender, but that's probably because I keep touching it. Otherwise, its not tender.

My breast/ nipple don't look like they are becoming tits, so I am not sure if it is gyno either. However, I was not sure how people first realize they might be having gyno- i.e., do you guys start feeling a lump under your nipple like I am?

I will order some arimidex anyway just to be on the safe side.

For you guys out there that have had gyno, does it ALWAYS effect both sides (i.e., both nipples, breast tissue) or can it sometimes effect one side more than the other?

Since I started feeling the small lump on my left side, I have never felt anything wierd on the right side.

 

[einstein1905]

We can all speculate as to whether or not is it's gyno, but what I'd do no matter what is start on Adex at .25mg/day throughout the remainder of your cycle (which should be done throughout every cycle) and run nolva at 40-60mg/day for 1 week with B6 at 200mg 3x/day for one week. After one week, continue to run the nolva at 10mg/day and B6 at 200mg/day.
A lump, tender or not, can very well still be gyno.
There's no good reason not to use preventative anti e's throughout every cycle (.25mg/day Adex and 10mg/day nolva).

 

[einstein1905]

LOL....

Oh man, that's a GREAT line, sounds like something Austin Powers would say... "It is ever so slightly tender, but that's probably because I keep touching it. "

If you are taking Novla, I seriously doubt it's gyno. I was on 500 test per week and my left nip did the exact same thing yours is doing.

I was near the end of my cycle though. This time it started up again on a new cycle, but I took primrose oil in large daily (3x) doses (per an old juicer), and it went away.

I'm not sure primrose oil works, or works in the same way, I can only tell you what it did for me.

BUT, I had no novla, no arimidex, and was desperate (it's on order now).

I'm not sure on DECA what dose it takes, I just know Novla doesn't help progesterone gyno.

I'm not an old pro, this is only my second cycle, but figured it would help you to know the same thing happened to me, I did NOTHING, and it was fine. Since you are doing Novla, you should be good, and IF you check on the DECA and find it's a safe dose (do a forum search here), you'll probably be fine.

As was mentioned earlier, prog/prolactin-related gyno usually occurs in the presence of elevated estrogen levels, so nolva certainly can help, even if it's prog/prol-related.

 

[jayce]

Man am I glad I never had a gyno prob.
Jayce

 

[Neodavid]

Help, or resolve... I read in another thread that Nolva didn't help with progesterone related gyno from Deca... are you saying it DOES resolve any problems, or helps a bit... Someone said something about needing Bromid with Deca, that's why I ask.

If you don't feel like answering, no biggie, I'll do the research.

As was mentioned earlier, prog/prolactin-related gyno usually occurs in the presence of elevated estrogen levels, so nolva certainly can help, even if it's prog/prol-related.

 

[einstein1905]

Help, or resolve... I read in another thread that Nolva didn't help with progesterone related gyno from Deca... are you saying it DOES resolve any problems, or helps a bit... Someone said something about needing Bromid with Deca, that's why I ask.

If you don't feel like answering, no biggie, I'll do the research.

It can help, but progestin induced gyno can also occur w/o estrogen, although very rare.

here's a thread with my take on things. No one really has put forth a very clear explanation/theory as to exactly how progestins cause gyno....this is my take:
http://forums.anabolicreview.com/showthread.php?t=96146&highlight=gyno

 

[Neodavid]

You are the man, Einstein.

It can help, but progestin induced gyno can also occur w/o estrogen, although very rare.

here's a thread with my take on things. No one really has put forth a very clear explanation/theory as to exactly how progestins cause gyno....this is my take:
http://forums.anabolicreview.com/showthread.php?t=96146&highlight=gyno

 

[micro]

B-6 at 200mg's 3x ed seems to help Prolatin Gyno. I have read reports of people starting to get gyno from tren and the B-6 helped them alot. Steroidology has some info on this.

 

[spound]

Squeeze your nip real hard and if any fluid comes out of it, then it is prob. Prog. gyno forming. This happened to me on deca. Why even risk growing titties? That will depress you even more than coming off a cycle with no PCT. I would get some bromo to run with that nolva, but I believe B6 will do the same thing...someone correct me if i am wrong about the B6 being similar to bromo.

 

[la_triathlete]

Squeeze your nip real hard and if any fluid comes out of it, then it is prob. Prog. gyno forming. This happened to me on deca. Why even risk growing titties? That will depress you even more than coming off a cycle with no PCT. I would get some bromo to run with that nolva, but I believe B6 will do the same thing...someone correct me if i am wrong about the B6 being similar to bromo.

I appreciate everyones input. I have started on the Nolva (50mg ED for a week- I am not a big guy- to be followed by 10mg ED for 3 weeks) and just ordered the Arimidex and Bromo. OK, this is a stupid question, but is B6 just vitamin B-6? If so, I would assume I could get it at any old drug store.

As for squeezing my nipple- while I knew it was a crazy idea, I did it just to see what would happen. Lets just say that my significant other will not be allowed to turn me on that way for at least the next 3 weeks. God, that fu*ken hurt. People, do yourselves a favor and if you ever start feeling something wierd in your tittie, feel it, DON'T SQUEEZE IT!!!!!

 

[la_triathlete]

Prog Gyno.

Hey guys, I was doing some reading on the prog induced gyno and found some stuff you might be interested in.

Progestrone is a promoter of breast tissue development and mammary gland arborization (branching). While alone, it does not seem to promote much breast tissue growth, progesterone does acts synergistically with EGF (epidermal growth factor) to influence cell division and mammary gland development (EGF is a major growth factor for mammary tissue, and has too many developmental effects to discuss here).

Progesterone acts through progesterone receptor positive cells, which represents a subset of non-proliferating epithelial cells that are capable of directing proliferation and/or differentiation of neighboring receptor negative cells. What this means is that not all cells have the progesterone receptor. Those that do will receive the progesterone signal and respond by secreting another signal (paracrine factor) that will be received by a neighboring cell that has the receptor for that signal. This signal will then tell that cell what to do- i.e., proliferate, differentiate, undergo apoptosis (programmed cell death vs. cell death due to necrosis/ injury). There seems to be a large requirement for paracrine factors to enhance the effects of progesterone, however, it is not yet known what these paracrine factors are.

I was looking up how AAS might induce progesterone or cause particular AAS to be metabolized into some sort of precursor, but I couldn't find anything. Maybe someone else on the board might want to pick up this topic.

Anyway, if you guys want to do your own reading, you might want to goto www.pubmed.gov which is the primary citation/ abstract listings for biomedical/ biological research.

 

[Neodavid]

LOL...

Friend of mine got drunk and tried to pierce himself in the nip. He CRIED!!! Didn't even get through.

I appreciate everyones input. I have started on the Nolva (50mg ED for a week- I am not a big guy- to be followed by 10mg ED for 3 weeks) and just ordered the Arimidex and Bromo. OK, this is a stupid question, but is B6 just vitamin B-6? If so, I would assume I could get it at any old drug store.

As for squeezing my nipple- while I knew it was a crazy idea, I did it just to see what would happen. Lets just say that my significant other will not be allowed to turn me on that was for at least the next 3 weeks. God, that fu*ken hurt. People, do yourselves a favor and if you ever start feeling something wierd in your tittie, feel it, DON'T SQUEEZE IT!!!!!

 

[einstein1905]

Hey guys, I was doing some reading on the prog induced gyno and found some stuff you might be interested in.

Progestrone is a promoter of breast tissue development and mammary gland arborization (branching). While alone, it does not seem to promote much breast tissue growth, progesterone does acts synergistically with EGF (epidermal growth factor) to influence cell division and mammary gland development (EGF is a major growth factor for mammary tissue, and has too many developmental effects to discuss here).

Progesterone acts through progesterone receptor positive cells, which represents a subset of non-proliferating epithelial cells that are capable of directing proliferation and/or differentiation of neighboring receptor negative cells. What this means is that not all cells have the progesterone receptor. Those that do will receive the progesterone signal and respond by secreting another signal (paracrine factor) that will be received by a neighboring cell that has the receptor for that signal. This signal will then tell that cell what to do- i.e., proliferate, differentiate, undergo apoptosis (programmed cell death vs. cell death due to necrosis/ injury). There seems to be a large requirement for paracrine factors to enhance the effects of progesterone, however, it is not yet known what these paracrine factors are.

I was looking up how AAS might induce progesterone or cause particular AAS to be metabolized into some sort of precursor, but I couldn't find anything. Maybe someone else on the board might want to pick up this topic.

Anyway, if you guys want to do your own reading, you might want to goto www.pubmed.gov which is the primary citation/ abstract listings for biomedical/ biological research.

Deca and tren convert to progestins (progesterone-like molecules), which act as a weak progesterone receptor agonist, but also, just like progesterone, can be prolactin receptor agonists. If you took a look at the link I provided earlier, I explained it in a little more detail. I'm holding strong to my theory, as it seems the most plausible mechanism IMO. I'd love to hear other's thoughts on it though.