Is There Such a Thing as an Aromasin Under-responder?

Exivious

New Member
The popular rough Aromasin/exemestane:Arimidex/anastrozole conversion seems to be 25:1 mg.

Anyone find they need more exemestane than this conversion rate suggests? I thought 10 mg ED was going to be more than enough for a 300/300 mg Test E/NPP cycle, even compensating a little for the (speculative?) effect of competition at the AR leading to more test being caught by aromatase than would be the case without NPP in the mix. It hasn't been enough, and while I'm responding better to higher doses after 5 days at 18 mg ED, I'm also getting headaches now (a known side of exemestane) and am still dealing with moodiness throughout the day and palps at night, though both are improving. I'm not putting up with daily headaches, though, and at this dose I don't even have enough to finish out the cycle. I'm going to begin carefully transitioning to tried-and-true anastrozole tonight.

I can't say for certain I'm an under-responder because I haven't been using pharm-grade Aromasin. The exemestane is UGL, though I trust the source. If it is underdosed, I would be surprised if it was significantly underdosed. Just wondering if anyone has had a similar experience requiring a much bigger dose than they'd expect based on adex/letro experience? My tolerable E2 threshold is lower than most guys, and that may have something to do with it. Maybe Type IIs are just a better fit for me.
 
There is a thing called under dosed

Yep, it's certainly a possibility. I would be surprised with this particular source, but like I said, I can't make a definitive claim regarding my own response to exemestane without using pharm-grade. I've acknowledged all that.

If no one here has had a similar experience requiring quite a bit more exemestane than they anticipated, then I'll conclude mine is significantly underdosed and not >80%. That's why I wanted input.

Ya it’s called bunk gear

Miss the part where I said I'm doing better after increasing the dose?
 
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Aromasin having a steroid-like structure ressembling that of androstenedione, it is best absorbed with a fatty meal.

Taking it on an empty stomach will considerably reduce its bioavailability.
 

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