Joints/Tendons/Bone

[Michael Scally MD]

Distal Triceps Tendon Injuries

KEY POINTS

· Distal triceps ruptures are uncommon injuries, usually caused by a fall on an outstretched hand or a direct blow.

· Eccentric loading of a contracting triceps has been associated with injury as well, particularly in professional athletes.

· Other common factors linked to injury are anabolic steroid use, weightlifting, and traumatic laceration.

· Some local and systemic risk factors include local steroid injection, hyperparathyroidism, and olecranon bursitis.

· The initial diagnosis can be complicated by pain and swelling, and a palpable defect is not always present

Distal triceps ruptures are uncommon, usually caused by a fall on an outstretched hand or a direct blow. Factors linked to injury include eccentric loading of a contracting triceps, anabolic steroid use, weightlifting, and traumatic laceration. Risk factors include local steroid injection, hyperparathyroidism, and olecranon bursitis. Initial diagnosis can be complicated by pain and swelling, and a palpable defect is not always present. Plain radiographs can be helpful. MRI confirms the diagnosis and directs treatment. Incomplete tears can be treated nonsurgically; complete tears are best managed surgically. Good to excellent restoration of function has been shown with surgical repair.

Walker CM, Noonan TJ. Distal Triceps Tendon Injuries. Clin Sports Med. 2020;39(3):673‐685. doi:10.1016/j.csm.2020.03.003 https://www.sportsmed.theclinics.com/article/S0278-5919(20)30026-0/abstract

 

[Michael Scally MD]

DHEA in Bone: The Role in Osteoporosis and Fracture Healing

Dehydroepiandrosterone (DHEA) is a metabolic intermediate in the biosynthesis of estrogens and androgens with a past clouded in controversy and bold claims. It was once touted as a wonder drug, a fountain of youth that could cure all ailments.

However, in the 1980s DHEA was banned by the FDA given a lack of documented health benefits and long-term use data. DHEA had a revival in 1994 when it was released for open market sale as a nutritional supplement under the Dietary Supplement Health and Safety Act.

Since that time, there has been encouraging research on the hormone, including randomized controlled trials and subsequent meta-analyses on various conditions that DHEA may benefit. Bone health has been of particular interest, as many of the metabolites of DHEA are known to be involved in bone homeostasis, specifically estrogen and testosterone.

Studies demonstrate a significant association between DHEA and increased bone mineral density, likely due to DHEA's ability to increase osteoblast activity and insulin like growth factor 1 (IGF-1) expression. Interestingly, IGF-1 is also known to improve fracture healing, though DHEA, a potent stimulator of IGF-1, has never been tested in this scenario.

The aim of this review is to discuss the history and mechanisms of DHEA as they relate to the skeletal system, and to evaluate if DHEA has any role in treating fractures.

Kirby DJ, Buchalter DB, Anil U, Leucht P. DHEA in bone: the role in osteoporosis and fracture healing. Arch Osteoporos. 2020;15(1):84. Published 2020 Jun 5. doi:10.1007/s11657-020-00755-y DHEA in bone: the role in osteoporosis and fracture healing

 

[rasengan]

i've heard that EQ actually increases tendon strength and can be stacked with test to sort of counter-act the test from impairing the tendons. was planning on including it in my next cycle when winter gets here , wanted to try a lower dose of test (500mg of Enanthate), 600mg of deca/ and a low dose of EQ to keep the tendons strong. the deca is awesome for collagen synthesis and helps with joint pain which is crucial for powerlifting ---- i found an article in my research file ..

While injecting test increases protein synthesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros are very prone to injury if they continue to lift very heavy, unless they cycle off T and let their collagen synthesis get back to normal. It's like having the skeletal muscle of a gorilla with the tendons of a very old man.

Winstrol increases collagen synthesis. It will give you bigger tendons. However, your body compensates for this by making them more brittle, weaker, and more prone to injury. I can't tell you how many bros work out anaerobically and become injured while on winstrol. Guys who lift in the 1-5 rep range while on winstrol, to baseball players who sprint all out from a stationary position -- winstrol should be the LAST drug they choose. Most of them like winstrol because they don't get the weight gain from it but it is very detrimental to bros who train for any sport anaerobically. Tendons tear easily on it.

Also, the drugs I mention increase collagen synthesis while also increasing collagen cross-linking integrity, making for a much stronger tendon.

Winstrol, on the other hand, will dramatically increase collagen syn, but ironically it decreases collagen cross-linking integrity, thus making a much weaker tendon.

You can plan a cycle of AAS which will increase collagen synthesis and skeletal muscle growth at the same time. The key is the drug(s) you choose.

Deca, Equipoise, Anavar, and Primobolan will ALL increase skeletal muscle while at the same time dramatically increase collagen syn and bone mass and density, leaving you with a substantially reduced chance of becoming injured than if you choose to use AAS like sus, cyp, or enth.

While testosterone will increase bone mass and density, even at supra-physiological levels, the result is weaker tendons due to inhibition of collagen syn.

To plan a cycle where the goal is to increase skeletal muscle mass/strength while at the same time increase joint/tendon/ligament strength, enough to keep up with the dramatic increase in skeletal muscle, you must choose drugs like Eq, Deca, Anavar, or Primo as the base of your cycle. Testosterone and its esters can be added to your cycle to keep levels within a 'normal' physiological range (ie, 100-200 mg/wk) but must not go above this. Since drugs like eq, deca, anavar and primo will reduce endogenous, natural levels of test, these levels may be maintained with exogenous test in the 100-200 mg/wk range. Test at this dose will not inhibit collagen syn, but paradoxically, will help increase it. It is when exogenous testosterone is used > 200 mg/wk that collagen syn is inhibited.

Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density. The one thing it does not give you is wood.

Primobolan, @ 5 mg/kg, will increase collagen synthesis by roughly 180% -- less than deca and equipoise but still substantial.

Equipoise @ 3 mg/kg will increase procollagen III by approximately 340% -- slightly better than deca.

Oxandrolone has over a hundred studies documenting its effectiveness at treating patients needing rapid increases in collagen syn to enhance healing.

These drugs have longer half-lives than most other AAS, so this should be considered when timing your post cycle clomid use. Here they are:

Deca: 15 days Equipoise: 14 days Primobolan: 10.5 days

Anavar has a half-life of only 8 hours so it should not pose a problem.

GH is probably the most remarkable drug at increasing collagen synthesis. It increases collagen syn in a dose dependant manner -- the more you use, the more you will increase collagen syn. It has also demonstrated this ability in short and long term studies. From what I've read, hGH at 6 iu/day increased the collagen deposition rate by around 250% in damaged collagen structures. This result indicates that the increased biomechanical strength of wounds to collagen structures treated with biosynthetic human growth hormone was produced by an increased deposition of collagen in the collagen structures.

Eq, primo, anavar, and deca are all good -- they increase several biomakers of collagen syn -- ie, type III, II, I, procollagen markers. GH just seems to do so most dramatically.

Use of any of these drugs @ supra-physiological levels with a maintenance dose of test will increase collagen syn while at the same time increase skeletal muscle mass. Skeletal muscle mass gains will not be as dramatic as with large testosterone doses but you have to weigh the risk/reward basis for yourself. Also, these drugs do not satisfy the libido like testosterone, but that is not the point of this thread. It is only to demonstrate that you can increase skeletal muscle and collagen syn at the same time with certain AAS --
i clicked on a link from here i dont want to advertise but heres the link What is Equipoise? | eHow.com

great article . i always use 250mg/week of test e and 125mg npp/ eod and get nice clean gains rather than doing 500mg of test and 500mg deca every week

 

[Michael Scally MD]

Testosterone, Dihydrotestosterone, Bone Density, and Hip Fracture Risk

Highlights
· Dihydrotestosterone (DHT) was associated with lower hip fracture risk in elderly men
· Testosterone (T) was not significantly associated with hip fracture risk
· DHT and T were not significantly related to bone mineral density
· DHT and T were similarly related to greater lean body mass

Background: Little is known about the relationships of dihydrotestosterone (DHT), a more potent androgen than testosterone (T), with bone mineral density (BMD) and fracture risk. Our objectives were to evaluate the relationships of T, DHT and sex hormone binding globulin (SHBG) with BMD, fracture risk, and lean body mass (LBM).

Methods: We evaluated 1128 older men free of cardiovascular disease in a prospective cohort study using data from the Cardiovascular Health Study. T and DHT were measured by liquid chromatography-tandem mass spectrometry and SHBG by fluoroimmunoassay. Our outcomes included incident hip fracture (n=106) over a median of 10.2 years and BMD and LBM by dual-energy x-ray absorptiometry (n=439).

Results: In Cox regression models mutually adjusted for T, SHBG, and covariates, each standard deviation increment in DHT (0.23 ng/ml) was associated with a 26% lower risk of hip fracture (adjusted hazard ratio [aHR] 0.74, 95% confidence interval (CI) 0.55-1.00, p=0.049). Similarly, SHBG was associated with fracture in mutually adjusted models (aHR HR 1.26, 95% CI, 1.01- 1.58, p=0.045). In contrast, T (aHR, 1.16, 95% CI, 0.86-1.56, p=0.324) was not significantly associated with fracture in mutually adjusted models. T, DHT and SHBG were not associated with BMD. T and DHT were both positively associated with LBM in individual models.

Conclusions: In older men, DHT was inversely associated with hip fracture risk and SHBG was positively associated with hip fracture risk, while T was not. Future studies should elucidate the mechanisms by which DHT affects bone health.

Rosenberg EA, Bůžková P, Fink HA, Robbins JA, Shores MM, Matsumoto AM, Mukamal KJ. Testosterone, Dihydrotestosterone, Bone Density, and Hip Fracture Risk among Older Men: The Cardiovascular Health Study. Metabolism. 2020 Oct 12:154399. doi: 10.1016/j.metabol.2020.154399. Epub ahead of print. PMID: 33058848. https://www.metabolismjournal.com/article/S0026-0495(20)30263-8/fulltext

 

[TRT@40]

Does this imply older men should add a little dht steroid to their prescription TRT to bring dht levels to the normal range, to lower hip fracture chances?!
@Michael Scally MD , does not DHT also contribute to growth of prostate cells?

 

[mands]

Does this imply older men should add a little dht steroid to their prescription TRT to bring dht levels to the normal range, to lower hip fracture chances?!
@Michael Scally MD , does not DHT also contribute to growth of prostate cells?

I would say a supplemental amount of DHT would have minimal or zero effect on prostate growth.

mands

 

[Michael Scally MD]

[OA] Acute Compartment Syndrome of The Deltoid

Background: Deltoid compartment syndrome is a rare entity. The purpose of this study was to report a recent case and perform a systematic literature review.

Methods: Patient data were gathered from chart review and clinical encounters. For the review, the MEDLINE, Embase, and Ovid databases were queried for deltoid compartment syndrome cases. Seventeen articles reporting on 18 patients with deltoid compartment syndrome were included.

Results: Including our patient, 9 of 19 patients (47.4%) presented with compartment syndrome limited to the deltoid. Most patients presented with additional affected compartments, most commonly in the ipsilateral arm (7 of 19, 37%). Isolated deltoid involvement often resulted from iatrogenic injury; of 10 iatrogenic reports, 8 involved only the deltoid.

Of 19 cases, 5 (26%) occurred in powerlifters, climbers, or anabolic steroid or testosterone injectors.

In 13 of 19 cases (68%), the patients were men aged 18-36 years, and only 1 female case (5%) was reported. Prolonged recumbence owing to substance abuse was documented in 6 of 19 cases (32%).

Conclusion: Deltoid compartment syndrome is rare, with only 19 reported cases, including our patient. Men are more commonly affected, and isolated deltoid compartment syndrome occurs in about 50% of reported cases. More than half of cases are iatrogenic, secondary to prolonged lateral decubitus positioning, injections, and surgical interventions about the shoulder. Prolonged recumbence from intoxication is also a common etiology. Providers should be aware of and recognize deltoid compartment syndrome to facilitate urgent surgical management.

Scollan JP, Bertsch ML, Flanagan CD, Chughtai M, Chepla KJ, Hoyen HA, Bafus BT. Acute compartment syndrome of the deltoid: a case report and systematic review of the literature. JSES Int. 2020 Sep 7;4(4):753-758. doi: 10.1016/j.jseint.2020.07.016. PMID: 33345211; PMCID: PMC7738586. https://www.jsesinternational.org/article/S2666-6383(20)30124-9/fulltext

 

[hghlover]

Whats the conclusion from this huge thread?

HGH is the big daddy for connective tissue?

 

[Michael Scally MD]

[OA] Point-of-care Ultrasound for Suspected Pectoralis Major Rupture: A Case Report

Introduction: Pectoralis major muscle injuries are relatively uncommon and occur secondary to weightlifting in nearly 50% of cases. Tendon tears occur almost exclusively in males between 20-40 years old and are heavily associated with anabolic androgenic steroid use.

While magnetic resonance imaging is often considered the modality of choice, its availability is often limited in the emergency department (ED). In contrast, point-of-care ultrasound (POCUS) is commonly available in the ED and can be used to help confirm the diagnosis and hasten disposition.

Case report: We report a case of a 28-year-old male competitive weightlifter with a history of chronic anabolic steroid use who presented to the ED with acute left shoulder pain after weightlifting. History and physical exam were concerning for pectoralis major rupture, and POCUS confirmed the diagnosis.

Conclusion: Prompt evaluation and radiographic confirmation is key in ensuring good patient outcomes in pectoralis major tears. Therefore, proficiency of emergency physicians in musculoskeletal POCUS as an adjunct to estimate the extent of injury is important for expediting disposition and and promptly involving orthopedic surgery evaluation.

Franks N, Gress J, Joseph R. Point-of-care Ultrasound for Suspected Pectoralis Major Rupture: A Case Report. Clin Pract Cases Emerg Med. 2021 Feb;5(1):93-96. doi: 10.5811/cpcem.2020.10.50802. PMID: 33560962. Point-of-care Ultrasound for Suspected Pectoralis Major Rupture: A Case Report

 

[Bumble]

i've heard that EQ actually increases tendon strength and can be stacked with test to sort of counter-act the test from impairing the tendons. was planning on including it in my next cycle when winter gets here , wanted to try a lower dose of test (500mg of Enanthate), 600mg of deca/ and a low dose of EQ to keep the tendons strong. the deca is awesome for collagen synthesis and helps with joint pain which is crucial for powerlifting ---- i found an article in my research file ..

While injecting test increases protein synthesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros are very prone to injury if they continue to lift very heavy, unless they cycle off T and let their collagen synthesis get back to normal. It's like having the skeletal muscle of a gorilla with the tendons of a very old man.

Winstrol increases collagen synthesis. It will give you bigger tendons. However, your body compensates for this by making them more brittle, weaker, and more prone to injury. I can't tell you how many bros work out anaerobically and become injured while on winstrol. Guys who lift in the 1-5 rep range while on winstrol, to baseball players who sprint all out from a stationary position -- winstrol should be the LAST drug they choose. Most of them like winstrol because they don't get the weight gain from it but it is very detrimental to bros who train for any sport anaerobically. Tendons tear easily on it.

Also, the drugs I mention increase collagen synthesis while also increasing collagen cross-linking integrity, making for a much stronger tendon.

Winstrol, on the other hand, will dramatically increase collagen syn, but ironically it decreases collagen cross-linking integrity, thus making a much weaker tendon.

You can plan a cycle of AAS which will increase collagen synthesis and skeletal muscle growth at the same time. The key is the drug(s) you choose.

Deca, Equipoise, Anavar, and Primobolan will ALL increase skeletal muscle while at the same time dramatically increase collagen syn and bone mass and density, leaving you with a substantially reduced chance of becoming injured than if you choose to use AAS like sus, cyp, or enth.

While testosterone will increase bone mass and density, even at supra-physiological levels, the result is weaker tendons due to inhibition of collagen syn.

To plan a cycle where the goal is to increase skeletal muscle mass/strength while at the same time increase joint/tendon/ligament strength, enough to keep up with the dramatic increase in skeletal muscle, you must choose drugs like Eq, Deca, Anavar, or Primo as the base of your cycle. Testosterone and its esters can be added to your cycle to keep levels within a 'normal' physiological range (ie, 100-200 mg/wk) but must not go above this. Since drugs like eq, deca, anavar and primo will reduce endogenous, natural levels of test, these levels may be maintained with exogenous test in the 100-200 mg/wk range. Test at this dose will not inhibit collagen syn, but paradoxically, will help increase it. It is when exogenous testosterone is used > 200 mg/wk that collagen syn is inhibited.

Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density. The one thing it does not give you is wood.

Primobolan, @ 5 mg/kg, will increase collagen synthesis by roughly 180% -- less than deca and equipoise but still substantial.

Equipoise @ 3 mg/kg will increase procollagen III by approximately 340% -- slightly better than deca.

Oxandrolone has over a hundred studies documenting its effectiveness at treating patients needing rapid increases in collagen syn to enhance healing.

These drugs have longer half-lives than most other AAS, so this should be considered when timing your post cycle clomid use. Here they are:

Deca: 15 days Equipoise: 14 days Primobolan: 10.5 days

Anavar has a half-life of only 8 hours so it should not pose a problem.

GH is probably the most remarkable drug at increasing collagen synthesis. It increases collagen syn in a dose dependant manner -- the more you use, the more you will increase collagen syn. It has also demonstrated this ability in short and long term studies. From what I've read, hGH at 6 iu/day increased the collagen deposition rate by around 250% in damaged collagen structures. This result indicates that the increased biomechanical strength of wounds to collagen structures treated with biosynthetic human growth hormone was produced by an increased deposition of collagen in the collagen structures.

Eq, primo, anavar, and deca are all good -- they increase several biomakers of collagen syn -- ie, type III, II, I, procollagen markers. GH just seems to do so most dramatically.

Use of any of these drugs @ supra-physiological levels with a maintenance dose of test will increase collagen syn while at the same time increase skeletal muscle mass. Skeletal muscle mass gains will not be as dramatic as with large testosterone doses but you have to weigh the risk/reward basis for yourself. Also, these drugs do not satisfy the libido like testosterone, but that is not the point of this thread. It is only to demonstrate that you can increase skeletal muscle and collagen syn at the same time with certain AAS --
i clicked on a link from here i dont want to advertise but heres the link What is Equipoise? | eHow.com

You anecdotally mention a 'maintenance dose of test' near the end. By definition, that still makes test the base compound, as it's required for any of the compounds mentioned, but none of the other individual compounds are required for all. Right?

You can up the percentage dose, but exogenous test will always be required.

Good info, though. Alot i hadnt read before

 

[hghlover]

You anecdotally mention a 'maintenance dose of test' near the end. By definition, that still makes test the base compound, as it's required for any of the compounds mentioned, but none of the other individual compounds are required for all. Right?

You can up the percentage dose, but exogenous test will always be required.

Good info, though. Alot i hadnt read before

No, this is not good info, it is complete bro science and if you want to heal injuries stay far away from steroids.

HGH, PRP and stem cells is what you want to look into

 

[Bumble]

No, this is not good info, it is complete bro science and if you want to heal injuries stay far away from steroids.

HGH, PRP and stem cells is what you want to look into

Not my point

 

[Minihulk82]

Did not read every page but I read the first few pages and the last few pages and to be honest, I think you just need to build your tendons up for a while before you get started with ANY STEROID.
I was always the hard-headed one who would get into the gym again and start my cycle as soon as I hit the gym again within the first month. My strength would go up pretty fucking fast along with my weight and everything else and then my tendon in my right elbow always gets injured. Every single time. No matter the drug or dosage. Deca, tren, eq, test, mast, anavar, you name it.
I actually injured my tendon about 12 years ago when I was arm wrestling somebody. Ever since then, it hasn't been right. I'll have to take off from the gym between three months to a year to let it recover and then when I come back after a few more months it's back to the same old shit.
This last time it was so bad I could not go all the way down on my bench press and I could not bring up dumbbells to press them. Curls sucked. Everything sucked but legs. Couldn't sleep at night I was in so much pain randomly.
Don't have insurance so I've always been putting off going to the doctor until NOW. I can't keep living the way I'm doing and wanting to be big, strong and a "bodybuilder".
Honestly don't know if I have tennis elbow, golfers elbow, or something else. Don't know how bad it is until I go to the doctor in 2 weeks.
hoping he can at least give me a cortisone shot for the time being until we can figure out what's going on, do rehab, surgery or whatever we need.

It fucking sucks. But yeah, eq and deca didn't help me one bit at all when I came to this tendon. None of my cycles. Just the right arm. Not the left at all. Fucking arm wrestling!!!!! Lol.

 

[Minihulk82]

about to start on 4ius of hgh and maybe bump it up to 6IUS of HGH for 6 months and see how that does also. My first time doing this, so we will see how it goes. The first 3 months I'm not going to touch any steroids and just do the HGH and light weight.

 

[Minihulk82]

I forgot to mention this. When I first started working out, I was only using creatine and having a great diet and had my own gym at my house. Probably worked out for nine months when I did the arm wrestling and I was NOT ON AAS when I first injured it. Had never tried it at this time. Lol.

 

[Bumble]

No, this is not good info, it is complete bro science and if you want to heal injuries stay far away from steroids.

HGH, PRP and stem cells is what you want to look into

Don't fool yourself. You're in an online steroid forum it is ALL, by defintion, bro science....bro.

 

[Minihulk82]

No, this is not good info, it is complete bro science and if you want to heal injuries stay far away from steroids.

HGH, PRP and stem cells is what you want to look into

I was actually reading on the PRP today when I was looking into my tendon injury. Seems like that is proven and it works and is better than cortisone shots because those are just temporary.

 

[Michael Scally MD]

Yam MGJ, Paramasivam Meenakshi Sundaram P, Ho SWL, Kwek EBK. Effectiveness of anabolic steroids in improving outcomes for post-operative hip fracture patients: A randomized controlled trial. J Clin Orthop Trauma. 2022 May 28;30:101913. doi: 10.1016/j.jcot.2022.101913. PMID: 35711820; PMCID: PMC9194567. https://www.journal-cot.com/article/S0976-5662(22)00149-7/fulltext

Background: Post-operative elderly hip fracture patients require significant rehabilitation. Nandrolone is an anabolic steroid used to promote muscle growth. This study aims to examine the effect of nandrolone in improving rehabilitation and quality of life in elderly female patients with hip fractures undergoing hemiarthroplasty.

Methods: This is a double-blinded prospective randomized-controlled-trial consisting of female patients above the age of 65 with an isolated neck of femur fracture planned for a hip hemiarthroplasty. Participants were randomized into two arms of the study - 50 mg intramuscular nandrolone vs normal saline placebo administered on post-operative day 0, and weeks 2, 6 and 12. The participants were followed up across a 1-year period following the surgery. Clinical outcomes such as time taken to achieve rehabilitation milestones, distance of ambulation and thigh muscle girth, and functional scoring with SF-36 questionnaire were recorded at intervals of 2, 6 and 12 weeks, 6 months and 1 year following the surgery.

Results: There were a total of 23 subjects with 11 in the steroid group and 12 in the placebo group. There was no significant difference in demographics and injury patterns between both groups. There was no significant difference for time taken to achieve various rehabilitation milestones and distance of ambulation. SF-36 scores on discharge and at 1-year follow-up mark were comparable. There was no difference in the complication rate between both groups.

Conclusion: Intra-muscular Nandrolone after hip surgery in elderly female patients does not result in short to mid-term improved rehabilitation or functional outcomes. Nandrolone did not result in increased short-term complications after hip surgery.

 

[Rido]

Yam MGJ, Paramasivam Meenakshi Sundaram P, Ho SWL, Kwek EBK. Effectiveness of anabolic steroids in improving outcomes for post-operative hip fracture patients: A randomized controlled trial. J Clin Orthop Trauma. 2022 May 28;30:101913. doi: 10.1016/j.jcot.2022.101913. PMID: 35711820; PMCID: PMC9194567. https://www.journal-cot.com/article/S0976-5662(22)00149-7/fulltext

Background: Post-operative elderly hip fracture patients require significant rehabilitation. Nandrolone is an anabolic steroid used to promote muscle growth. This study aims to examine the effect of nandrolone in improving rehabilitation and quality of life in elderly female patients with hip fractures undergoing hemiarthroplasty.

Methods: This is a double-blinded prospective randomized-controlled-trial consisting of female patients above the age of 65 with an isolated neck of femur fracture planned for a hip hemiarthroplasty. Participants were randomized into two arms of the study - 50 mg intramuscular nandrolone vs normal saline placebo administered on post-operative day 0, and weeks 2, 6 and 12. The participants were followed up across a 1-year period following the surgery. Clinical outcomes such as time taken to achieve rehabilitation milestones, distance of ambulation and thigh muscle girth, and functional scoring with SF-36 questionnaire were recorded at intervals of 2, 6 and 12 weeks, 6 months and 1 year following the surgery.

Results: There were a total of 23 subjects with 11 in the steroid group and 12 in the placebo group. There was no significant difference in demographics and injury patterns between both groups. There was no significant difference for time taken to achieve various rehabilitation milestones and distance of ambulation. SF-36 scores on discharge and at 1-year follow-up mark were comparable. There was no difference in the complication rate between both groups.

Conclusion: Intra-muscular Nandrolone after hip surgery in elderly female patients does not result in short to mid-term improved rehabilitation or functional outcomes. Nandrolone did not result in increased short-term complications after hip surgery.

That's really unfortunate. I would have thought it may have helped prevent muscle wasting. I guess rehabilitation protocol is solid enough that using drugs won't make as big of a difference

 

[Chuck Spears]

So what's the consensus on boldenone and tendonits?
The 12 year old OP claims its one of the best for collagen synthesis but there's not much on google to back that up.
Anyone have personal experience?
Please dont post some apeshit medical study. I'm too tarded for those.