Long Term Testosterone/AAS Use Causes Hyperplasia?¯\_(ツ)_/¯

[RoidyNoob]

I was listening to this scientist ( specialized in sports and sports meds) who works with IFFB Pro Ben Pakulski, saying that long term test use can cause hyperplasia in muscle. He didn't expand on it, if I remember correctly.
What do you guys think?
I thought only through growth hormone, growth factors; peptides in general was hyperplasia achievable.
¯\_(ツ)_/¯

 

[RoidyNoob]

Nevermind found an of article on it. LOL
Effects of Long Term Supplementation of Anabolic Androgen Steroids on Human Skeletal Muscle

 

[Redrum42]

HGH= hyperplasia is a myth, or at the very least, greatly exaggerated. HgH is for fat loss.. Not sure about testosterone

 

[RoidyNoob]

HGH= hyperplasia is a myth, or at the very least, greatly exaggerated. HgH is for fat loss.. Not sure about testosterone

What supports your statements?

 

[Redrum42]

What supports your statements?

Effects of growth hormone on skeletal muscle. - PubMed - NCBI

Regulation of muscle mass by growth hormone and IGF-I

Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?

I can look more if you like. The general consensus seems to be if you are deficient, yes it will help you grow. Otherwise, probably won't make a huge difference. If there is any effect, it is only indirectly through IGF-1. And we've yet to see amazing results from that either. There are not many articles I could find only talking about supraphysiological doses, which could be telling. If you could find articles completely disproving all this, great, I have found this debate interesting for years because of how much money people spend on it without the blatantly obvious effects (and research) of AAS.

 

[RoidyNoob]

Effects of growth hormone on skeletal muscle. - PubMed - NCBI

Regulation of muscle mass by growth hormone and IGF-I

Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?

I can look more if you like. The general consensus seems to be if you are deficient, yes it will help you grow. Otherwise, probably won't make a huge difference. If there is any effect, it is only indirectly through IGF-1. And we've yet to see amazing results from that either. There are not many articles I could find only talking about supraphysiological doses, which could be telling. If you could find articles completely disproving all this, great, I have found this debate interesting for years because of how much money people spend on it without the blatantly obvious effects (and research) of AAS.

Damn! Doesnt this change everything?

 

[Redrum42]

Damn! Doesnt this change everything?

Not sure honestly. Sometimes real world effects differ slightly because of many many factors that aren't present in labs.

There is still the indirect effect possible with both AAS and HGH increasing circulating IGF-1 levels. I don't know enough if circulating IGF levels increase muscle mass or hyperplasia or if they do, to what level.