Looking to start 2x weekly injections of hgh (5-10iu) at night for recovery from gym and work.

[AlexDavis43]

I hear you. My diet is very clean, I am reasonably lean, and do a significant amount of cardio. No GH my A1c is 5.1 - 5.2 and running 2.5 IU GH nightly it ran up to 5.6.

I think my baseline A1c should be lower and the A1c creep on lower dose GH is a concern.

I understand the concern about GH-induced A1c creep but it doesn't get much lower than 5 in anyone.

I don't know the purpose of A1c but it seems like the body likes to maintain ~5 under normal/healthy conditions. Ie, lower may not be better.

 

[UncleBuns]

I understand the concern about GH-induced A1c creep but it doesn't get much lower than 5 in anyone.

I don't know the purpose of A1c but it seems like the body likes to maintain ~5 under normal/healthy conditions. Ie, lower may not be better.

My no GH A1c is acceptable. Low dose GH putting it at the line of pre diabetic is not though. Also, I made a typo on that original post. It was only 2.2 IU GH nightly that got A1c up to 5.6. That'a a pretty low dose. GH is game changer for me though so I just use some ancillaries for blood sugar and all is well.

I'm on the conservative side health wise, at least for an AAS user. I'm planning to maximize my body and do it for a long time yet. Maybe a bit paranoid, but acceptably so IMO.

 

[clearheaded]

Can you cite your study?

I’ve seen 13-20 hours for restart to begin, and 72 hours for full production. Believe it was a Type-IIX post that had the study. If I have free time tonight I’ll try and dig it up. This also jives with the proctols I’ve seen for ghrp/ghrh + hgh together. Curious where you’re seeing 4 days to restart?

google isoform approach GH, doping, WADA etc.. they studied GH on ATHLETES and found that it takes 4 days for is-forms to re establish.. ie they can detect GH use no matter if took ur shot 8 hrs ago and ur levels are "normal" as you will have a different ratio ie higher 22da GH isoform. anyway, of course need someone to look up the data, however if it takes 4 days for natural ratio of GH to be excreted one assumes it takes that long for it to re establish SOME natural production.. now how much longer it takes for GH to get back up to baseline I dont know but presumably longer than 4 days. but for the study they just wanted to see there testing window they could reliably determine the ratios skewed.

type likely is talking about this study for doping however I dont think we can say "full production" as 4 days is when RATIOs become normal which is different than full production. also ALOT of variables and dont think we KNOW full production ever comes back due to testing issues with serum GH testing so I dont think anyone can KNOW without 100s of tests wether there GH came back the same of 95% of what it was any changes in insulin BG of course change things aswell.

anyway, could be wrong but when people say 12 hours or a day essentially means 0 or low shut down of large night pulse which I think is not realistic esp when talking months/years and not weeks, IMO of course.

 

[clearheaded]

I understand the concern about GH-induced A1c creep but it doesn't get much lower than 5 in anyone.

I don't know the purpose of A1c but it seems like the body likes to maintain ~5 under normal/healthy conditions. Ie, lower may not be better.

ive had couple GF with a1c in the mid 4s. no diabetes in family and 95+ yo grandmas, they get hangry easy, but can eat alot and stay trim

 

[AlexDavis43]

Can you cite your study?

I’ve seen 13-20 hours for restart to begin, and 72 hours for full production. Believe it was a Type-IIX post that had the study. If I have free time tonight I’ll try and dig it up. This also jives with the proctols I’ve seen for ghrp/ghrh + hgh together. Curious where you’re seeing 4 days to restart?

Here's what I found. They suggested 32 hours which seems easy for any athlete to evade without unannounced surprise tests.

 

[songsofpyramids]

Here's what I found. They suggested 32 hours which seems easy for any athlete to evade without unannounced surprise tests.

That does seem easy to beat. What I’m talking about that I need to dig out is about pituitary shutdown during exogenous hgh use. I’ll try and dig it out if I ever get free time this week.

 

[clearheaded]

so would seem 100% shut down(yes assumption but reasonable IMO) anywhere from 32-72 hrs ie before SOME GH starts to be released(or at least start producing normal ratio). also the study Alex posted id be interested if was long term use or they just gave subjects 1 dose.. perhaps can explain discrepancy, as I think its reasonable the longer term use would likely increase time the ratio isn't natural at least some.

yes easy to get around testing forsure. GHRP/sermorelin prob impossible to get busted for as can delay testing for 2 hrs no issue so even if walked in as u injected u could pass although may catch some of the tail end of elevated gh. or for big boys imagine have china produce multiple is-forms.

pyramids I dont think u will find an answer to what ur looking for as they dont study gh use in healthy folks other than for testing purposes.. even a good proxy like GHRH/P isn't really going to give reliable data. id be interested if any couches actually tested GH levels and got any sort of consistency in the #s for non abusing athletes. what I mean is really need patients to be hooked to a machine that takes blood sample every hour or so for many days and not just random snapshot from a blood draw, my guess anyway.

 

[AlexDavis43]

so would seem 100% shut down(yes assumption but reasonable IMO) anywhere from 32-72 hrs ie before SOME GH starts to be released(or at least start producing normal ratio). also the study Alex posted id be interested if was long term use or they just gave subjects 1 dose.. perhaps can explain discrepancy, as I think its reasonable the longer term use would likely increase time the ratio isn't natural at least some.

Agree we probably won't see good or relevant data on this, but I don't think endogenous GH gets shut down hard long-term with prolonged hGH use (unlike doing a cycle of testosterone on endogenous testosterone production).