Markimus Rex
New Member
What's it like at that dosage?
MESO-Rx
Anabolic Steroids
Minimum Nandrolone dose before neurotoxicity
- Thread starter Ricky93
- Start date
xrayphoton13
Member
MWF is plenty. Type-IIx said phenylprop is close enough to enanthate that you could even do twice weekly
RockyP
Member
No side effects. Lots of fullness noticeable increase in strength. Quite enjoyable.
nandrolone gets a bad rep for lots of water retention. Obviously there will be some as with most other anabolics but I’ve cut and bulked in nandrolone several times and that aspect is more dependent upon diet / carbs / salt / cardio than nandrolone itself. However keep in mind I do use lower dosages. Perhaps at 600 mg a week things to get pretty watery no matter what.
dinfar1337
New Member
its the face man, its the deca face
On "modified keto" - very low carb / high protein - i have no issues.
I know, sounds like a dumb BB diet.
Tdeck81
Banned
How's that for a easy easy eating plan...?
Increasing your muscle mass during a rigorous weight loss diet? - Excel Male Health Forum
Hypoenergetic diet–induced weight loss results in ∼20–30% of mass lost as lean body mass (LBM), with the remaining mass lost from adipose tissue. So normally you can expect for every 10 pounds of body weight you lost to also lost 2-3 pounds of muscle tissue. However, is there a way to avoid...
www.excelmale.com
Weird. I get it.
Tdeck81
Banned
Not really. My diet was shit for a long time. My Step one was eliminating processed foods (usually dinner sides) and replacing with more vegetables and meat. Step two was opting for leaner cuts of meat and better veggies (beets/kale). Unintended but wonderful side effect, satiated with reduced portion sizes. I’m slowly cutting down on my breads and pasta but man it’s hard. I love food.
In truth I’m slowly working towards a similar “goal” diet. My experience with atkins, circa 2003?, was ketosis for like 2-3 months then start slamming carbs. Never titrated up and found a carb balance. As I’ve aged diet has become more critical. Excercise is not the work around it was in the past.
I appreciate you sharing.
I will level with you. I can eat what I eat and keep sub 12% pretty easy.
Have a challenged myself to go back to trad. BB diet and see if I can do better? Nope. Would be alot harder mentally for me.
Eating protein and fat simple.
Add in carbs, hold on tight! Cravings galore.
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Going back and implementing this would be a cool experiment.
View: https://youtu.be/epa0hbpZcFw
will take some work.
View: https://youtu.be/epa0hbpZcFw
will take some work.
You can't think of it as "food". It is not your friend. It is only fuel, building blocks. Do not make friends with food. It doesnt care about you. Use it as a tool to pile on the slabs of veiny, striated muscle the best you can.
That dude was a machine. That fruit plate gives me a mild anxiety attack, lol.
Tdeck81
Banned
Layman’s terms is so much more palatable. It’s easy for me to get discouraged with technical jargon but his break down makes it doable.
Kralteramon
Member
I wonder. What is the minimum dose of alcohol needed for neurotoxicity?
boophomet
Member
Curious if that converts into DHN more easily, since transdermal testosterone results in higher levels of DHT
RockyP
Member
You ain’t kidding. My DHT was over 250 on transdermal TNE
boophomet
Member
Did that nuke your hairline?
malfeasance
Member
So in this pretty good overview, the memory function impairment in rats was linked to androgen receptors in the hippocampus.The Impact of Nandrolone Decanoate on the Central Nervous System - PMC
Nandrolone is included in the class II of anabolic androgenic steroids (AAS) which is composed of 19-nor-testosterone-derivates. In general, AAS is a broad and rapidly increasing group of synthetic androgens used both clinically and illicitly. AAS ...pmc.ncbi.nlm.nih.gov
Pretty good overview.
"This region displays a relatively high density of androgen receptors in rats, which suggests a relationship between the androgen receptor and cognitive function."
Is there any reason to think that humans have a relatively high density of androgen receptors in the limbic brain or hippocampus? They seem to be noting this a distinguishing feature of the rat brain.
So I went to the study that was cited in the overview.
Nandrolone decanoate administration elevates hippocampal prodynorphin mRNA expression and impairs Morris water maze performance in male rats - PubMed
The misuse of anabolic androgenic steroids has in several reports been associated with effects resulting in altered behavior. This study used the Morris water maze task to investigate the effect of high doses of the anabolic androgenic steroid nandrolone on spatial learning and memory in male...
pubmed.ncbi.nlm.nih.gov
"The hippocampus, a brain region associated with cognitive function, was analyzed for mRNA expression of prodynorphin, the precursor of dynorphinergic peptides. The results indicated that the transcription levels of prodynorphin were significantly elevated in the animals treated with nandrolone compared with controls."
Again, is this an issue in humans?
Also, would this have continued after they stopped injecting nandrolone into the rats? Is it permanent?
malfeasance
Member
Also, growth hormone seems to make some improvement in rats, reversing nandrolone's effects and improving spatial memory
pubmed.ncbi.nlm.nih.gov
GH improves spatial memory and reverses certain anabolic androgenic steroid-induced effects in intact rats - PubMed
GH has previously been shown to promote cognitive functions in GH-deficient rodents. In this study we report the effects of GH on learning and memory in intact rats pretreated with the anabolic androgenic steroid nandrolone. Male Wistar rats received nandrolone decanoate (15 mg/kg) or peanut oil...
pubmed.ncbi.nlm.nih.gov
malfeasance
Member
And note in that last one that nandrolone caused a weight decrease in rats, which growth hormone was able to attenuate.
Weird.
Weird.
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