Dayum thats pretty damn good
MESO-Rx
Anabolic Steroids
Nebivolol for lowering RHR
- Thread starter y777
- Start date
rexy
Member
I've tried 2.5mg but it doesn't tend to do a great deal for HR. It may be enough if you were just on TRT and it will certianly be a nice additional alongside 80mg Telm at that dose. But it will not do much for HR at that dose as you scale up - Nebivolol's HR effects even at 10mg can be fairly mild if you're prone to RHR increases but it will put downward pressure on BP still. I've learned to leverage it at 5mg for it's basic vasodilation, BP and decent beta blocking effects for general cardio protection whilst on TRT or low doses - it helps to reduce anxiety spikes too because of it reducing physical HR response to it, as I'm prone to beta adrenergic stimulation from anything, not just PEDs.
But as for actual gear-related HR when doses go up, it'll struggle against high doses or combinations of Tren, HGH and other things even at 10mg. I find going from 5mg-15mg does nothing to furthe reduce HR once the heat is on with Test, Tren and HGH, or even Nand - and it becomes best for BP control. Then, I've found it's better to leverage Ivabradine instead. Especially because Nebivolol can put too much downward pressure on BP at the higher doses and would do so in your case when used alongside Telm.
However, Nebivolol does hold off against reflex tachycardia unless you are ridiculously low on BP, because it's downregulating the beta stimulation that is used to produce that effect. Reflex tachycardia is most likely when systolic BP falls below 90 mmHg.
Anyway - It's just great for it's general protective effects and BP assistance year round and I include it yes but at 5mg. 2.5mg is better than none alongside TRT, but you could judge it based on whether it puts your BP too low or not at 5mg.
For actual cycling at moderate-high levels with numerous compounds, it will level off quickly in effect on HR around 5mg, and 10mg will be barely noticable for that purpose, but still help with BP at that dose.
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I agree with everything, at 10mg it's useless in my opinion Vs 5mg for the HRH reduction and if you need better BP it's best to add another BP meds at low moderate dosage then to increase one that is already at a good dosage.
Plus at 10mg it started being a lot less cardio selective for me. Didn't reduce RHR but it hindered me in having a proper good high HR during physical activity and that's horrible to experience. Running or exercising and feel your HR that needs to go higher without being able too it's not a good feeling trust me.
For BP control I would go the classical Telmi 80mg + Nebi 5mg if that's not enough add a diuretic indapamide or a CCB like Cilnidipine if you have access to it or lercanidipine/lacidipine. Both at the starting dosage respectively 10mg/4mg
If that's not enough add the diuretic if you haven't already.
Studies shows it's better to take multiple bp meds at low dosages then just a few at high dosages.
About the HR yeah ivabradine seems the best option if you can't fix the HR with nebivolol, any other BB fuck up our training performance badly.
Ivabradine doesn't.
rexy
Member
I agree, it starts to become a mess at 10mg and not as selective.
At one point, I ended up at 100/65 BP on it whilst on Test/Tren/GH with no other meds included that were impacting it, and would have periods of 15-30 mins in the mornings where blood flood wasn't getting to my finger tips properly and they'd be numb. It wasn't HGH causing that because I had no issue until Neb went to 10mg consistently. My memory got noticably worse until dropping it back to 5mg, and I also would feel faint after a hard set sometimes as if my blood flow was being restricted because HR couldn't go high enough.
TLDR: wont use 10mg Neb again
xrayphoton13
Member
In my experience 80mg telmisartan didn't do enough on blast to get me below 120 so I switched to 40mg telmisartan with 5mg amlodipine which is a CCB. The combo worked much better than 80mg telmisartan. No hit to gym performance or cardio either. Bonus that Amlodipine is probably one of the cheapest things on the PCT Indian pharma websites
I don't like amlodipine edema is a recurring side effect. I like 80mg telmi for other side benefit that are supposedly activated at that dosage, as I said in my post if one can't control with telmi I would add nebivolol unless you have already a low HR in that case a CCB is a perfect addition but there are much better one then amlodipine: Cilnidipine - lercanidipine - lacidipine.
All three have same BP reduction but almost no edema, we are talking 30% of amlodipine Vs 3/4% of laci and lerca (Cilnidipine no edema)
xrayphoton13
Member
Interesting! Is that 30% of amlodipine users that will develop edema? I haven't noticed any on myself. I'll look into the others you mentioned to see what cost looks like and availability. Thanks
Yeah 30+% of amlodipine users developed peripheral edema, the risk of having it increase with times after 6+ months it doubles and after 1 year it's even higher.
Of course you could be one that will not get it. Using an ACEi will reduce that % tho.
Don't remember if using an ARB helps too.
But those 3 other names of CBB I gave you are far superior in all regards to amlodipine.
Cilnidipine is only available from India Japan Korea so you need to get it from pct24x7
The other two are available in both USA and Europe.
Photon
Member
Would you by any chance know if there's a source that can get stuff from Japan? Not Cilnidipine, looking for some non steroid pharma stuff instead..
Ive been looking around but cant seem to find a Japan source..
BamaCrazy
Banned
Here’s my plan. I’m currently taking 30mg Telmisartan (cutting a 20mg pill) at night, and 5mg Nebivolol in the morning. I didn’t like the way Telmisartan and Nebivolol made me feel at night when taken together but mornings are working. I stopped Amlodipine when I started having freaky hand edema. Once the Cilnidipine gets delivered this week I’m adding that at night also and reducing Telmisartan back down to 20mg. I bought the 5mg and 10mg Cilnidipine so I will start low on the 5s first.
Then I’ll check my BP for a few days and adjust from there. I want to keep the dosages as low as possible for all 3.
If i take Nebi 5mg in the morning i literally fall asleep. I only take it in the evenings for that reason, normal RHR is at 85 avg with 5mg Nebi mine goes down to 67 avg. (also with 40mg Telmi)
BamaCrazy
Banned
My RHR on Nebivolol still hovers around 76-80 so no issues there. Part of that might be the Reta but I’m happy with that number. I cannot go higher with Telmisartan because my potassium quickly gets out of range. Hopefully 20/5/5 will work perfectly without the need to increase.
Keep us updated and good luck, always curious learn more about peoples experience
Ghoul
Member
This is my worst nightmare.
A guy who's given me endless shit using something I recommended to get healthier and live longer to give me more shit lol ...
Seriously I hope it works out great, and we have no first hand experiences mentioned here so your review will be useful.
If you ever get around to using 40mg Telm and a stable dose of Cilnipidine, there are endless single pill combos available,
Anyway:
I want to get below 115/75, which is the number where the rate of arterial plaque buildup falls off a cliff.
I'm at low 120s with Telm 40 and 5mg Amlodipine. I was thinking of adding Chlorthalidone to go down the rest of the way.
Thinking Telm 40/ Cilnipidine 10 / 6.25 or 12mg Chlorthalidone
I've never used a diuretic. Any likely issues at this dose? Would HCTZ be better? As usual the "potential" bad outcomes sound terrifying, but I know those are unlikely. as these wouldn't be so commonly prescribed. Does it make you piss a lot more? Like middle of the night?
@Sampei I thought you said something about diuretics before but I'm not certain.
Sorry for the offtopic but love the new avatar
BamaCrazy
Banned
My goal is 110/70. I’ve tried HCTZ in the past and it made me feel terrible even at low doses. A diuretic as the 4th compound makes sense but I’m going to have to do a little more research if I get to the point where it’s needed.
xrayphoton13
Member
I've used hctz before bed and I definitely do get up about twice as much to pee throughout the night. So if it's usually twice that increases to four for me
Check indapamide it's a superior diuretic for BP in anyway.
Only one I have found that doesn't impact insulin sensitivity, it's extended release so one pill in the morning as soon as you wake up and that's it. Yeah you piss a little bit more but not by much, just drink a lot as that's good in general.
It helps your kidney too, studies have shown that indapamide helped ppl with CKD disease and impaired egfr fo increase creatinine clearance. Something other diuretic didn't.
But before adding the diuretic why not try nebivolol at 5mg? Unless you suffer of low HR already in that case yeah go for the indapamide first
BamaCrazy
Banned
What about ED on Indapamide? I try to avoid medications that make Little Me lazy.
Something I've never heard anyone talking about is the effect of Beta Blockers on anxiety, which is a pretty interesting benifit if that's something you deal with.
