MESO-Rx Sponsor Opti USA DOMESTIC - HGH, INJECTABLES, TABLETS, PEPTIDES, & MISC

[benfrankparkway]

any word of possible black friday sale?

 

[Suprachica79]

9 days T/D - def not matching the website estimates.

 

[1Megaman]

5 day T/A

 

[Xplicit]

Stupidest post I’ve read. So you went from using a very low and effective dose of 2iu to using EOD at more then 10x the initial dose that was originally giving u sides. Some of yous talk to make conversation I swear.

Yes, I went from 2iu ED that I could not tolerate at all... to 10x the dose administered 3x a week that I could tolerate.

You don't have to agree with the dosage but that's not why I made the post. I made the post to demonstrate that EOD or 3x a week might be a viable alternative for anyone who is struggling with HGH sides on an ED schedule, like I was.

 

[B Ware]

Yes, I went from 2iu ED that I could not tolerate at all... to 10x the dose administered 3x a week that I could tolerate.

You don't have to agree with the dosage but that's not why I made the post. I made the post to demonstrate that EOD or 3x a week might be a viable alternative for anyone who is struggling with HGH sides on an ED schedule, like I was.

Got any labs? Would be interesting to see. Guys who take high doses never share labs for some reason which is odd since those guys should be pulling labs more than most.

 

[intensedrive]

I see the new Orange Tops are listed on the website. Anyone concerned about the purity, and having a small Dimer? Still worth the price?

 

[BrockSamson42]

I see the new Orange Tops are listed on the website. Anyone concerned about the purity, and having a small Dimer? Still worth the price?

I feel like I recall the orange top supplier delivering a sub par, (or straight bad) batch of orange tops awhile back. Like 88% purity.

My guess is the goal was 240iu like last batch, hit 210iu... purity is the lowest on meso atm (I think), I took a pass on them. Was waiting for them to restock but nah, below 95% is a failed pharmacopeia pass from me. His Orange top supplier really seems inconsistent. Dunno why he uses him.

 

[Black Beard]

I highly recommend anyone new to HGH or having strong side effects like this try an EOD dosing schedule. I went from not being able to run 2iu ED due to sides, to running 9-12 vials a week with a 3x a week dosing approach.

x 3 per week and EOD significantly mitigates the side effects caused by insulin resistance.


What sides were you getting on 2 IU daily?

 

[Xplicit]

Got any labs? Would be interesting to see. Guys who take high doses never share labs for some reason which is odd since those guys should be pulling labs more than most.

Admittedly, I am over due for labs. I plan on getting some before I add Tren in January. I cruised in Sept to mid Oct and was supposed to get labs then but got caught up in a ton of overtime and soaked it up while I could.

I have more but here are just a few of the most recent ones from this year. I have some estrogen checks too and I should have a thyroid lab somewhere from this summer that shows 75mcg having me in range with TSH.

Edit - I also have an echocardiogram from end of 2021 that is pristine. Was very happy when I got those results. Would like to get another one next year.

Pre Blast labs in February.

End of May lipid profile on the below stack (rough guess, I titrated doses up starting mid April)

1000mg To 1500mg Test
1000mg To 1500mg EQ
Mast 400-600mg
15-18iu Grey tops/Black tops ED (split into 3x a week)
75mcg T3
No AI (June labs have estrogen sensitive lab on it, EQ keeps me down low, I am actually very estrogen sensitive. I am about to trial arimidex alongside my current Test/EQ even though I know my e2 is low, to see if I can focus the E1 down and if it provides any benefit).

End of June lipid profile. I was on the ^ same stack but I added Tren Ace at 300mg right after May labs got back. Can see the effect in the June lipid profile. Now that I can run testosterone (I literally haven't been able to use more than **EDIT** TRT doses of testosterone for the last 10 years), I plan to limit Tren to 6-8 week runs finishing up blasts just based on how hard it hits my labs/bp. I would love to find a way to run a mere 75-150mg purely to take advantage of it pulling IGF into the muscle but frankly I do change on it, not in a terrible way but not in a way I want to put my spouse through constantly.

I have other labs but nothing super relevant, was obsessed with my ACR (Kidney function) last year and this year fighting with a life insurance policy. A pre HGH IGF test at 178, but never tested IGF on the HGH. I might do that in January before I start the Tren.

I check my blood glucose once or twice a week upon waking, sits in the 80s. I did hit a 99 a week ago but I have been sick for 2-3 weeks, back down to 84 this morning.

Kidneys are my main concern. BP sits 140s/80s on anything over 1G Test 1G EQ or if Tren is in the mix. Otherwise, I have it controlled 120/70s off cycle or on lower doses with a Valsartan/Nebivolol combo (I add 25mg HCTZ on blast, doctor prescribed but honestly don't feel like it does much).

I take about 30-40 OTC pills every day via support supplements. Potentially more.

Started in April 6'2 220lbs and hit 272lbs 3 weeks ago before I got sick. I want to say I am 6'1 now though, lifting weights compacts my spine, I "grew" an inch during my 2 years off the gym.

I had rebound gains waiting for me, had been out of the gym for 2 years prior, I work in medical and this lifestyle had to take a backdoor during and after covid.

262lbs this morning going back to the gym after my 2-3 week illness. I would like to hit 280 by end of February. HGH as of today is equiv to 23iu ED via 3 greytops and 1 blacktop vial injected 3x a week. I will go to 5 vials in mid December and I just brought Insulin in for the first time right before I got sick at 20ius 3x a week Humulin R before my evening meals (I stagger my calories heavily favoring 6pm to 10pm, I have reasons).

HGH in the future will not be this high. 10-15iu on blasts, 5iu cruise.

Protein has been at 400+ but I might come down a little. Calories pre sickness were 5k+ daily and scale was moving slow. I will push them higher here shortly, I do not care if I gain fat during this process, even still I eat somewhat clean if only to feel good and over the last few years I have seen the positive effect it has on labwork.

Ive put up pictures in the past on another forum, for a purpose. I like this forum, will likely post pictures here as well but not just yet.

Wall of text, dont have to read it all, but its there. If I missed any black out on my lab attachments, please give me a heads up.

 

[Xplicit]

x 3 per week and EOD significantly mitigates the side effects caused by insulin resistance.


What sides were you getting on 2 IU daily?

In the past I got away with a short stint of HGH around 10-15 iu ED but I ignored the carpel tunnel and I have no doubt my blood sugar was sky high, as I was not monitoring it back then nor taking any glucose supplements to help control it. Ulnar nerve progressively got more and more fried to the point I lost the use of half my left hand and majority of my left arm was numb.

In general, my nervous system wasn't happy with me at that time because I had used DNP a little too long prior to the HGH addition and landed myself some peripheral neuropathy.

Took me 4 months of Keto diet with TB500 and BPC to regain function (something I had 2 different specialists tell me wasn't possible).

Ever since ^ that, if I touched even 2iu a day the ulnar nerve would flare up bad (as well as my peripheral neuropathy) and I would have to quickly drop it.

No longer have this issue.

I also use to bloat heavily on HGH, and I mean heavily. 3x a week has certainly helped reduce that, but I also attribute my ability to run HGH better now to the Valsartan I take for my BP.

 

[138casanova]

Been using Opti for three years now. Ordered from website back on 11/9 and haven’t received my order or any correspondence from the website or Opti. Sent him an email with my BTC receipt last week and haven’t gotten a response. Just sent another email a few minutes ago. I have never had a single issue. Not worried yet, but definitely not what I’m used to. I’ll keep you posted.

 

[malfeasance]

Admittedly, I am over due for labs. I plan on getting some before I add Tren in January. I cruised in Sept to mid Oct and was supposed to get labs then but got caught up in a ton of overtime and soaked it up while I could.

I have more but here are just a few of the most recent ones from this year. I have some estrogen checks too and I should have a thyroid lab somewhere from this summer that shows 75mcg having me in range with TSH.

Edit - I also have an echocardiogram from end of 2021 that is pristine. Was very happy when I got those results. Would like to get another one next year.

Pre Blast labs in February.

End of May lipid profile on the below stack (rough guess, I titrated doses up starting mid April)

1000mg To 1500mg Test
1000mg To 1500mg EQ
Mast 400-600mg
15-18iu Grey tops/Black tops ED (split into 3x a week)
75mcg T3
No AI (June labs have estrogen sensitive lab on it, EQ keeps me down low, I am actually very estrogen sensitive. I am about to trial arimidex alongside my current Test/EQ even though I know my e2 is low, to see if I can focus the E1 down and if it provides any benefit).

End of June lipid profile. I was on the ^ same stack but I added Tren Ace at 300mg right after May labs got back. Can see the effect in the June lipid profile. Now that I can run testosterone (I literally haven't been able to use more than **EDIT** TRT doses of testosterone for the last 10 years), I plan to limit Tren to 6-8 week runs finishing up blasts just based on how hard it hits my labs/bp. I would love to find a way to run a mere 75-150mg purely to take advantage of it pulling IGF into the muscle but frankly I do change on it, not in a terrible way but not in a way I want to put my spouse through constantly.

I have other labs but nothing super relevant, was obsessed with my ACR (Kidney function) last year and this year fighting with a life insurance policy. A pre HGH IGF test at 178, but never tested IGF on the HGH. I might do that in January before I start the Tren.

I check my blood glucose once or twice a week upon waking, sits in the 80s. I did hit a 99 a week ago but I have been sick for 2-3 weeks, back down to 84 this morning.

Kidneys are my main concern. BP sits 140s/80s on anything over 1G Test 1G EQ or if Tren is in the mix. Otherwise, I have it controlled 120/70s off cycle or on lower doses with a Valsartan/Nebivolol combo (I add 25mg HCTZ on blast, doctor prescribed but honestly don't feel like it does much).

I take about 30-40 OTC pills every day via support supplements. Potentially more.

Started in April 6'2 220lbs and hit 272lbs 3 weeks ago before I got sick. I want to say I am 6'1 now though, lifting weights compacts my spine, I "grew" an inch during my 2 years off the gym.

I had rebound gains waiting for me, had been out of the gym for 2 years prior, I work in medical and this lifestyle had to take a backdoor during and after covid.

262lbs this morning going back to the gym after my 2-3 week illness. I would like to hit 280 by end of February. HGH as of today is equiv to 23iu ED via 3 greytops and 1 blacktop vial injected 3x a week. I will go to 5 vials in mid December and I just brought Insulin in for the first time right before I got sick at 20ius 3x a week Humulin R before my evening meals (I stagger my calories heavily favoring 6pm to 10pm, I have reasons).

HGH in the future will not be this high. 10-15iu on blasts, 5iu cruise.

Protein has been at 400+ but I might come down a little. Calories pre sickness were 5k+ daily and scale was moving slow. I will push them higher here shortly, I do not care if I gain fat during this process, even still I eat somewhat clean if only to feel good and over the last few years I have seen the positive effect it has on labwork.

Ive put up pictures in the past on another forum, for a purpose. I like this forum, will likely post pictures here as well but not just yet.

Wall of text, dont have to read it all, but its there. If I missed any black out on my lab attachments, please give me a heads up.

WOW

 

[Opti]

Been using Opti for three years now. Ordered from website back on 11/9 and haven’t received my order or any correspondence from the website or Opti. Sent him an email with my BTC receipt last week and haven’t gotten a response. Just sent another email a few minutes ago. I have never had a single issue. Not worried yet, but definitely not what I’m used to. I’ll keep you posted.

Thank you to the member(s) that made me aware of @138casanova post.

@138casanova, I just checked my email and I have no email from you in my inbox or spam folder. Can you double check the email address you are using?

opti.usa@protonmail.com

Please email at your convenience. I apologize for any frustration this has caused.

 

[138casanova]

Thank you to the member(s) that made me aware of @138casanova post.

@138casanova, I just checked my email and I have no email from you in my inbox or spam folder. Can you double check the email address you are using?

opti.usa@protonmail.com

Please email at your convenience. I apologize for any frustration this has caused.

Thanks for the quick response! That’s the email I have been using, but just forwarded it again. It’s coming from my proton mail with a diff name, but I referenced my user name here in the body of it. Thanks, everyone!

 

[138casanova]

Thanks for the quick response! That’s the email I have been using, but just forwarded it again. It’s coming from my proton mail with a diff name, but I referenced my user name here in the body of it. Thanks, everyone!

Update: we got it figured out, and in true Opti fashion, he went above and beyond and added something extra. Thanks again! Have a happy Thanksgiving, everyone!

 

[whitedeath23]

Just had another order touch down. 4 days.

 

[AlexDavis43]

I see the new Orange Tops are listed on the website. Anyone concerned about the purity, and having a small Dimer? Still worth the price?

@Type-IIx recently commented on dimer and it's speculated effects. You might check that out first.

Also, how do you mean "worth the price?"

Worth the potential [minimal] health risk? Worth it for $/IU GH?

 

[AlexDavis43]

x 3 per week and EOD significantly mitigates the side effects caused by insulin resistance.

What is the evidence for this? You said "significantly" which implies a high degree of confidence in the importance and validity of this statement.

Have you seen any studies on this? Please link if so

 

[Type-IIx]

What is the evidence for this? You said "significantly" which implies a high degree of confidence in the importance and validity of this statement.

Have you seen any studies on this? Please link if so

Ciresi A, Cicciò F, Radellini S, Guarnotta V, Calcaterra AM, Giordano C. More Favorable Metabolic Impact of Three-Times-Weekly versus Daily Growth Hormone Treatment in Naïve GH-Deficient Children. Int J Endocrinol. 2017;2017:8469680. doi: 10.1155/2017/8469680.

Chung YS, Lee HC, Hwang SK, Paik IK, LeeJH, Huh KB. Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration. J Korean Med Sci. 1994 Apr;9(2):169-78. doi: 10.3346/jkms.1994.9.2.169.

Basically, t.i.w. administration benefits metabolic parameters (HOMA-IR, a measure of insulin resistance & fasting insulin) but at the expense of IGF-I increases & anabolism that depends largely on IGF-I & insulin activities.

 

[AlexDavis43]

Ciresi A, Cicciò F, Radellini S, Guarnotta V, Calcaterra AM, Giordano C. More Favorable Metabolic Impact of Three-Times-Weekly versus Daily Growth Hormone Treatment in Naïve GH-Deficient Children. Int J Endocrinol. 2017;2017:8469680. doi: 10.1155/2017/8469680.

Chung YS, Lee HC, Hwang SK, Paik IK, LeeJH, Huh KB. Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration. J Korean Med Sci. 1994 Apr;9(2):169-78. doi: 10.3346/jkms.1994.9.2.169.

Basically, t.i.w. administration benefits metabolic parameters (HOMA-IR, a measure of insulin resistance & fasting insulin) but at the expense of IGF-I increases & anabolism that depends largely on IGF-I & insulin activities.

Sir! Thank you for posting these references.

For anyone interested in reading, both full texts are available online:

More Favorable Metabolic Impact of Three-Times-Weekly versus Daily Growth Hormone Treatment in Naïve GH-Deficient Children

Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration