To mitigate health effects keep doses at lowest effective dose for shortest amount of time necessary. My vote goes to test, rGH, primo, oxandralone, and low dose mast. I like mast but higher doses really fuck with my joints. Also a big fan of peptides like bpc 157, TB 500, and GH peptides.
If you find what dose of test and rGH keeps your health markers in good order and feeling great you can do a lot just on those. A couple times a year you can do a low/moderate blast for 8 - 12 weeks that is "reasonably" low health risk. And keep your health supps in the mix always. I take fish oil, ubiquinol, D3, magnesium, zinc, niacinamide, NAC as well as a very in check whole food diet. Rarely or never any processed foods, sugar drinks, or alcohol. Keep cardio in the mix all year.
If you want to maximize health though probably just trt within normal male range, 2iu GH max, and HCG. Any anabolics over normal range will likely effect health but it's proportional to the harshness of the compound, dose, and length of use.